Carrier Free,ExactAb™,Low Endotoxin,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE&SEC-HPLC),See COA Azide Free,Carrier Free,ExactAb™,Low Endotoxin,PBS Only,Validated para fluxos de trabalho cromatográficos e analíticos sensíveis que exigem interferência mínima da linha de base.

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Armazenamento e envio

Store at -80°C,Avoid repeated freezing and thawing Envio Dry ice packs + Cold packs. Consulte o COA específico do lote para obter as especificações exatas.

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Documentos de qualidade

SDS, COA, ficha técnica e folha de especificações disponíveis para download. COA específico do lote acessível por meio de pesquisa por número de lote.

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Comprovação documental

Citado em 0 publicações revisadas por pares nas áreas de cromatografia, síntese orgânica e reações de acoplamento cruzado.

Visão geral

Mouse anti Human CXCR4/CD184 Antibody, Monoclonal (12G5), could be used for Block, Flow, ICC, IF, IHC, Neutralization, WB and so on.
Application
Block: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
ICC/IF: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
Neutralization: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
Protein Function
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.

Especificações

Product Name

CXCR4/CD184 Mouse mAb - Primary antibody, specific to CXCR4/CD184, Mouse IgG2a

Sinónimos

Especificações e pureza

Carrier Free,ExactAb™,Low Endotoxin,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE&SEC-HPLC),See COA

Espécie hospedeira

Mouse

Especificidade

CXCR4/CD184

Conjugação

Unconjugated

Grau

Azide Free, Carrier Free, ExactAb™, Low Endotoxin, PBS Only, Validated

Isótipo

Mouse IgG2a

Tipo de corrente de luz

kappa

Método de purificação

Protein A/G purified

Concentração

See COA

Product Line

Produtos biológicos

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -80°C,Avoid repeated freezing and thawing

Enviado em

Dry ice packs + Cold packs

Estabilidade e armazenamento

Store at 4°C short term (1-2 weeks). Store at -80°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

Flow Cytometry: CXCR4/CD184 Mouse mAb (Ab098344)

CXCR4/CD184 Mouse mAb (Ab098344) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CXCR4/CD184 with CXCR4/CD184 Mouse mAb (Ab098344) conjugated with biotin (right panel) at 1.0 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: CXCR4/CD184 Mouse mAb (Ab098344)

CXCR4/CD184 Mouse mAb (Ab098344) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CXCR4/CD184 (red) with CXCR4/CD184 Mouse mAb (Ab098344) conjugated with biotin at 1.0 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

SEC: CXCR4/CD184 Mouse mAb (Ab098344)

CXCR4/CD184 Mouse mAb (Ab098344) - SEC
The purity of CXCR4/CD184 Mouse mAb (Ab098344) is more than 95% verified by HPLC.

Aplicação

Dilution info