M2698: Selective Kinase Inhibitor for Research Applications

M2698 is a research-grade small-molecule inhibitor (Aladdin SKU M650774, cross-referenced as MCE HY-100501) supplied for use in cell signaling and kinase pathway studies.

Product Name

M2698

SKU

M650774

Cross-Reference

MCE HY-100501

Product Class

Small-molecule research inhibitor

Primary Application

Kinase pathway and cell signaling research

Supplier

Aladdin Scientific

Product Overview

M2698 (Aladdin SKU M650774) is a small-molecule compound supplied for research use in the life sciences. It is cross-referenced with the MCE catalog number HY-100501, allowing researchers to align experimental protocols and published literature that cite this identifier. As a research reagent, M2698 is intended for in vitro and cell-based assays investigating kinase activity and downstream signaling pathways. It is not approved for clinical or veterinary use.

Mechanism and Biological Activity

M2698 is reported in the literature under the MCE reference HY-100501 as a selective inhibitor targeting specific kinase signaling nodes relevant to cell proliferation and survival. Small-molecule kinase inhibitors of this class typically function by competing with ATP at the kinase active site, thereby blocking phosphorylation of downstream substrates and modulating pathway output. Researchers should consult primary literature associated with HY-100501 for detailed IC50 values, selectivity panels, and cellular efficacy data, as Aladdin Scientific presents this compound consistent with peer-reviewed characterization.

Note: Specific IC50 values and selectivity data are not reproduced here pending verification against primary sources; see Review Flags.

Recommended Applications and Usage Guidelines

M2698 is suitable for the following research applications:

• In vitro kinase assays: Determination of inhibitory potency against target and off-target kinases.
• Cell-based signaling studies: Assessment of pathway modulation, phosphoprotein profiling, and downstream gene expression changes.
• Mechanistic studies: Investigation of kinase-dependent phenotypes including proliferation, apoptosis, and migration assays.

For optimal results, reconstitute M2698 in the solvent recommended in the associated technical datasheet (typically DMSO). Prepare fresh working dilutions in aqueous buffer or cell culture medium immediately before use to minimize compound degradation. Final DMSO concentrations in cell-based assays should be kept at or below 0.1% to avoid cytotoxic artefacts unless otherwise validated.

Storage, Handling, and Safety

Store M2698 as directed on the product datasheet, typically at −20 °C in a desiccated environment protected from light, moisture, and repeated freeze-thaw cycles. Upon receipt, aliquot the compound into single-use volumes to preserve potency. Handle all research chemicals in accordance with institutional safety guidelines: wear appropriate personal protective equipment (gloves, lab coat, eye protection) and work in a well-ventilated area or fume hood. Refer to the Safety Data Sheet (SDS) provided with the product for full hazard classification, first-aid measures, and disposal instructions compliant with local regulations.

Ordering Information and Technical Support

M2698 is available from Aladdin Scientific under SKU M650774. To place an order, contact your regional Aladdin Scientific representative or visit the product page on the Aladdin Scientific website. For technical questions regarding experimental design, solubility, or compound characterization, the Aladdin Scientific technical support team is available via email and phone. Bulk quantities and custom packaging may be available upon request; please contact sales for a quotation. When ordering, reference both the Aladdin SKU (M650774) and the MCE cross-reference (HY-100501) to ensure accurate fulfillment.

Frequently asked questions

What is the MCE cross-reference number for M2698?

M2698 (Aladdin SKU M650774) corresponds to MCE catalog number HY-100501. Researchers can use this cross-reference to locate published protocols and peer-reviewed studies associated with this compound.

In what solvent should M2698 be reconstituted?

M2698 is typically reconstituted in DMSO as indicated on the product datasheet. Working dilutions should be prepared in aqueous buffer or cell culture medium immediately before use, keeping the final DMSO concentration at or below 0.1% in cell-based assays unless otherwise validated.

How should M2698 be stored to maintain stability?

M2698 should be stored at −20 °C in a desiccated, light-protected environment. Avoid repeated freeze-thaw cycles by aliquoting the compound into single-use volumes upon receipt. Refer to the product datasheet for compound-specific stability data.

Is M2698 suitable for in vivo studies?

M2698 is supplied as a research reagent intended primarily for in vitro and cell-based assays. Suitability for in vivo use depends on formulation, pharmacokinetic properties, and institutional approval. Researchers should review the primary literature and consult Aladdin Scientific technical support before designing in vivo experiments.

How can I order M2698 in bulk or request a custom package size?

Bulk quantities and custom packaging of M2698 (SKU M650774) may be available upon request. Please contact your regional Aladdin Scientific sales representative and reference the SKU M650774 and MCE cross-reference HY-100501 when making your inquiry to receive an accurate quotation.

References

1. MedChemExpress (MCE) product page for HY-100501. Accessed via MCE catalog.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.