1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Animal models of acute lung injury are used to simulate alveolar epithelial and pulmonary vascular endothelial injury, inflammatory cell infiltration, disruption of the alveolar-capillary barrier, pulmonary edema, and hypoxemic respiratory dysfunction. They are important experimental systems for ...
CRISPR/Cas9 is currently one of the most widely used targeted gene editing technologies. It can generate DNA breaks at specific sites through RNA-guided Cas9 nuclease activity and achieve gene knockout, targeted knock-in, point mutation construction, and functional screening by using the ...
Animal models of acute liver injury are used to simulate hepatocellular necrosis, inflammatory responses, oxidative stress, cholestasis, or metabolic disorders occurring within a short period of time. They are important experimental systems for studying mechanisms of liver injury, evaluating ...
Copper ion content determination is commonly used in water quality, soil, food, feed, biological samples, alloy leachates, electroplating wastewater, and related systems. Chromogenic methods are suitable for rapid routine laboratory determination of copper content. However, different chromogenic ...
Alkaline phosphatase (ALP/AKP) activity assays are used to evaluate the hydrolytic capacity of samples toward phosphate monoesters. They are commonly applied in studies of osteogenic differentiation, bone metabolism, hepatobiliary injury, enzyme-labeled reactions, microbial metabolism, and ...
Animal models of gastric ulcer are used to simulate gastric mucosal barrier disruption, acid-related injury, inflammatory infiltration, oxidative stress, and ulcer repair processes. Model selection should be centered on the research objective: ethanol- or NSAID-induced models are commonly used ...
The proteolytic enzyme network in cell injury involves calpains, caspases, cathepsins, MMP/ADAM family proteases, and the ubiquitin-proteasome system. Different proteolytic enzymes correspond to Ca²⁺ overload, apoptotic execution, lysosomal injury, extracellular matrix remodeling, and ...
Antibacterial agents are fundamental tools in microbiology, antimicrobial susceptibility testing, resistance mechanism studies, infection model construction, and antibacterial activity evaluation. When selecting antibacterial agents for research, priority should be given to the target of action, ...
The SOCS family comprises key negative feedback regulators in the JAK-STAT pathway. SOCS proteins limit sustained activation of cytokine signaling and influence immune cell differentiation, inflammatory response intensity, tissue injury, and disease model phenotypes. When studying SOCS1, SOCS2, ...