1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Not every new scaffold can become a practical building block in medicinal chemistry. For a new structure to be truly noteworthy, it should answer at least three questions at the same time: Can it introduce a clear three-dimensional structural change? Can it be prepared reliably on a sufficient ...
Iron content detection is used to evaluate total iron, ferrous iron, ferric iron, or bioavailable iron levels in water samples, foods, soils, plants, cells, serum, tissues, and fermentation systems. Common methods can be divided into colorimetric assays and instrumental analytical methods. TPTZ, ...
In their study Deoxyfluorination of Hydroxy-Substituted Boronates, published in ACS Organic & Inorganic Au, Melnyk and co-workers reported a deoxyfluorination method for hydroxyalkyl-substituted aryl/alkenyl boronates. This method converts an alcohol hydroxyl group into a C–F bond, namely a ...
Red acid biological dyes are not a group of “red dyes” that can be freely substituted for one another. Acid fuchsin is more commonly used for histological counterstaining and collagen/muscle background staining. Acid Red 44 and Acid Red 66 are often used in trichrome staining-related ...
The core value of classical histological special staining is to further distinguish structures such as muscle fibers, collagen fibers, elastic fibers, reticular fibers, fibrin, and neuroglial fibers on the basis of HE staining. PTAH, Masson, VG, elastic fiber staining, and reticular fiber ...
Urinary protein biomarker detection is used to determine the source of proteinuria, the degree of filtration barrier injury, and whether tubular injury is also present. Albumin, transferrin, IgG, and α2-macroglobulin differ in molecular size and in the conditions under which they enter urine. ...
The cytoskeleton is a dynamic fibrous network composed of microfilaments, microtubules, and intermediate filaments, mainly consisting of actin, tubulin, and different types of intermediate filament proteins. The cytoskeleton not only maintains cell morphology, cell polarity, and intracellular ...
The endocrine system maintains body homeostasis through hormone secretion, target organ responses, and feedback regulation. Hormones regulate glucose and lipid metabolism, growth and development, reproductive function, stress responses, water and electrolyte balance, bone metabolism, and energy ...
RNA-DNA hybrids are nucleic acid structures formed by pairing between an RNA strand and a DNA template strand. Typical forms include transcription-associated R-loops and hybrid regions formed after ribonucleotides are incorporated into DNA. RNase H1, RNase H2, helicases, topoisomerases, and ...
