KLHL2 Mouse mAb - Primary antibody, specific to KLHL2

Cat. No.: Ab112273

GRADE & PURITY See COA

Application

Flow Cytometry, IF/ICC, WB

Host species

Mouse

Reactive species

Human, Mouse, Rat

Isotype

Mouse IgG2b

Clone Number

OTI6D8

Conjugation

Unconjugated

Visão geral

Mouse anti Human KLHL2 Antibody, Monoclonal (OTI6D8), could be used for WB, IF/ICC, Flow Cytometry and so on.

Specifications

Product Name

KLHL2 Mouse mAb - Primary antibody, specific to KLHL2

Sinónimos

ABP KELCHantibody | Actin binding protein Mayvenantibody | Actin-binding protein Mayven antibody | kelch antibody | kelch like 2 antibody | Kelch like 2 | Kelch like family member 2 antibody | Kelch like protein 2 antibody | Kelch-like protein 2 antibody

Especificações e pureza

See COA

Mecanismos bioquímicos e fisiológicos

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, WNK1, WNK3 and WNK4, leading most often to their proteasomal degradation (PubMed:23838290). The BCR(KLHL2)

Espécie hospedeira

Mouse

Especificidade

KLHL2

Imunogénio

Recombinant protein of human KLHL2 (AA 1-100 & 494-593) produced in HEK293T cell.

Controlo positivo

WB: HEK293T transfected with pCMV6-ENTRY KLHL2 cDNA for 48 hrs; Jurkat lysates. IF/ICC: COS7 cells transiently transfected with pCMV6-ENTRY KLHL2. Flow Cytometry: HEK293T cells transfected with pCMV6-ENTRY KLHL2.

Conjugação

Unconjugated

SDS-PAGE

150 kDa

Método de purificação

Protein A purified

Concentração

See COA

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -20°C,Avoid repeated freezing and thawing

Enviado em

Ice chest + Ice pads

Estabilidade e armazenamento

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Aplicação

• Aplicação: Dilution info
• WB:

  1/500-1/2000 ;

• Flow Cytometry:

  1/100;

• IF/ICC:

  1:100 ;

Alvos associados (humanos)

KLHL2 Tbio Kelch-like protein 2 (0 Activities)

Discover Target: KLHL2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Perguntas frequentes

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (KLHL2 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.