Lendalizumab (anti-Complement C5) - Primary antibody, specific to C5, Human IgG2SA

CAS: 2210314-30-8 Cat. No.: Ab191930

GRAU & PUREZA Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Human

Reactive species

Human

Isotype

Human IgG2SA

Conjugation

Unconjugated

Visão geral

Lendalizumab (anti-Complement C5) is a proprietary antibody that targets the complement protein C5a with potential immunomodulating and anti-inflammatory activities.

Especificações

Product Name

Lendalizumab (anti-Complement C5) - Primary antibody, specific to C5, Human IgG2SA

Sinónimos

Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen

Especificações e pureza

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Mecanismos bioquímicos e fisiológicos

Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex i

Espécie hospedeira

Human

Especificidade

C5

Conjugação

Unconjugated

Grau

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Tipo de ação

INHIBITOR

Isótipo

Human IgG2SA

Tipo de corrente de luz

kappa

SDS-PAGE

145 kDa

Método de purificação

Protein A purified

Concentração

See COA

CAS

2210314-30-8

Product Line

Produtos biológicos

Armazenamento e envio

Condições de armazenamento de armazenamento

Store at -80°C,Avoid repeated freezing and thawing

Enviado em

Dry ice packs + Cold packs

Estabilidade e armazenamento

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

ELISA: Lendalizumab (anti-Complement C5) (Ab191930)

Lendalizumab (anti-Complement C5) (Ab191930) - ELISA
Immobilized Recombinant Human Complement C5 protein at 2.0 μg/mL can bind Lendalizumab (anti-Complement C5) (Ab191930) with the EC₅₀ of 2.58 ng/mL.

SEC: Lendalizumab (anti-Complement C5) (Ab191930)

Lendalizumab (anti-Complement C5) (Ab191930) - SEC
The purity of Lendalizumab (anti-Complement C5) (Ab191930) is more than 95% verified by HPLC.

Alvos associados (humanos)

C5 Tclin Complement C5 (0 Activities)

Discover Target: C5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Perguntas frequentes

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2210314-30-8.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Lendalizumab (anti-Complement C5)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.