LRRK2
57 produtos
Produtos
- MLi-2, Inhibitor of leucine rich repeat kinase 2CAS: 1627091-47-7 Fórmula: C21H25N5O2 Peso molecular: 379.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: M276039Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (2R,6S)-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1H-indazol-3-yl]pyrimidin-4-yl]morpholine
- SMILES
- CC1CN(CC(O1)C)C2=NC=NC(=C2)C3=NNC4=C3C=C(C=C4)OC5(CC5)C
- InChIKey
- ATUUNJCZCOMUKD-OKILXGFUSA-N
- InChI
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- Sinónimos
- (2R,6S)-2,6-Dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1H-indazol-3-yl]pyrimidin-4-yl]morpholine | cis-2,6-Dimethyl-4-...
- IndazoleSolid ≥99%● Em estoque — Armazém nos EUA, envio para a EU* Item #: I157585Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 1H-indazole
- SMILES
- C1=CC=C2C(=C1)C=NN2
- InChIKey
- BAXOFTOLAUCFNW-UHFFFAOYSA-N
- InChI
- 1S/C7H6N2/c1-2-4-7-6(3-1)5-8-9-7/h1-5H,(H,8,9)
- Sinónimos
- 1,2-Benzopyrazole | F0918-7060 | F1918-0009 | Indazole, 6 | UNII-7C4VQE5C03 | 1H-indazol | EINECS 205-978-4 | FT-0627...
- IKK-16 (cloridrato)CAS: 1186195-62-9 Fórmula: C28H29N5OS • HCl Peso molecular: 520.09Solid ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: I274699Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- [4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone;hydrochloride
- SMILES
- C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5.Cl
- InChIKey
- XFVDIVQCZWDBCW-UHFFFAOYSA-N
- InChI
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- Sinónimos
- Cloridrato de N-(4-(4-pirrolidina-1-il-piperidina-1-il)-[4-(4-benzo[b]tiofen-2-il-pirimidina-2-ilamino)fenil]carboxamida
- IKK-16 (Inibidor VII da IKK)● Em estoque — Armazém nos EUA, envio para a EU* Item #: I129698Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- [4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone
- SMILES
- C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5
- InChIKey
- BWZJBXAPRCVCKQ-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- (4-((4-(1-Benzothiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | 873225-46-8 (fr...
- GNE7915, Inhibitor of leucine rich repeat kinase 2;Inhibitor of TTK protein kinaseCAS: 1351761-44-8 Fórmula: C19H21F4N5O3 Peso molecular: 443.4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: G275946Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- [4-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoro-5-methoxyphenyl]-morpholin-4-ylmethanone
- SMILES
- CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC
- InChIKey
- XCFLWTZSJYBCPF-UHFFFAOYSA-N
- InChI
- 1S/C19H21F4N5O3/c1-3-24-16-12(19(21,22)23)10-25-18(27-16)26-14-9-13(20)11(8-15(14)30-2)17(29)28-4-6-31-7-5-28/h8-10H,3-7H2,1-2H3,(H2,24,25,26,27)
- Sinónimos
- [4-[[4-(Ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-methanone | (4-(...
- GSK2578215ACAS: 1285515-21-0 Fórmula: C24H18FN3O2 Peso molecular: 399.42● Em estoque — Armazém nos EUA, envio para a EU* Item #: G166851Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
- SMILES
- C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4
- InChIKey
- WCIGMFCFPXZRMQ-UHFFFAOYSA-N
- InChI
- 1S/C24H18FN3O2/c25-23-14-19(10-12-27-23)18-8-9-22(30-16-17-5-2-1-3-6-17)21(13-18)24(29)28-20-7-4-11-26-15-20/h1-15H,16H2,(H,28,29)
- Sinónimos
- 5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide | Benzamide, 5-(2-fluoro-4-pyridinyl)-2-(phenylmetho...
- JH-II-127CAS: 1700693-08-8 Fórmula: C19H21ClN6O3 Peso molecular: 416.87● Em estoque — Armazém nos EUA, envio para a EU* Item #: J275343Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone
- SMILES
- CNC1=NC(=NC2=C1C(=CN2)Cl)NC3=C(C=C(C=C3)C(=O)N4CCOCC4)OC
- InChIKey
- HUEKBQXFNHWTQQ-UHFFFAOYSA-N
- InChI
- 1S/C19H21ClN6O3/c1-21-16-15-12(20)10-22-17(15)25-19(24-16)23-13-4-3-11(9-14(13)28-2)18(27)26-5-7-29-8-6-26/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24,25)
- Sinónimos
- [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone | [4-[[...
- LRRK2-IN-1, Inhibitor of leucine rich repeat kinase 2CAS: 1234480-84-2 Fórmula: C31H38N8O3 Peso molecular: 570.7Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: L125224Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one
- SMILES
- CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC
- InChIKey
- IWMCPJZTADUIFX-UHFFFAOYSA-N
- InChI
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- Sinónimos
- BRD-K01436366-001-01-6 | 2,6-Diamino-hexanoic acid; hydrochloride | BDBM50379529 | 2-((2-Methoxy-4-(4-(4-methylpipera...
- CZC 2514610mM in DMSO● Em estoque — Armazém nos EUA, envio para a EU* Item #: C420850Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F
- InChIKey
- XXHHOTZUJIXPJX-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide；CZC-25146；...
- CZC 25146Solid ≥98%(HPLC)● Em estoque — Armazém nos EUA, envio para a EU* Item #: C287537Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F
- InChIKey
- XXHHOTZUJIXPJX-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide | CZC-2514...
- CZC 54252 hydrochloride● Em estoque — Armazém nos EUA, envio para a EU* Item #: C288538Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide;hydrochloride
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl
- InChIKey
- KWCBHUPLQMUKAF-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochlor...
- CZC-25146 hydrochloride● Em estoque — Armazém nos EUA, envio para a EU* Item #: C412508Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide;hydrochloride
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F.Cl
- InChIKey
- SKYQTYQDKAOHLP-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- CZC-25146(hydrochloride) | 1330003-04-7 | N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]p...
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Perguntas frequentes
Which compounds are listed for LRRK2?
Compounds associated with LRRK2 are grouped here under the Autophagy classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does LRRK2 sit within Autophagy?
LRRK2 is one target listing within the Autophagy classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from LRRK2?
For compounds listed under LRRK2, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for LRRK2?
Browse the parent Autophagy listing to reach targets neighbouring LRRK2, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.