Epigenética

Explore compostos orientados para vias metabólicas destinados à investigação em epigenética, incluindo ferramentas relevantes para a regulação da cromatina e o controlo transcricional. Utilize esta página para comparar moléculas utilizadas em fluxos de trabalho de validação de alvos, estudos de mecanismos e modulação do estado celular.

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  1. SB 218078, Inhibitor of checkpoint kinase 1
    CAS: 135897-06-2 PubChem CID: 3387354 Fórmula: C24H15N3O3 Peso molecular: 393.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ◐ .Sob encomenda · 8–12 semanas Item #: S287033
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    Identificadores técnicos
    Nome IUPAC
    28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-3,5-dione
    SMILES
    C1CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C1O2)C7=C53)C(=O)NC6=O
    InChIKey
    OTPNDVKVEAIXTI-UHFFFAOYSA-N
    InChI
    1S/C24H15N3O3/c28-23-19-17-11-5-1-3-7-13(11)26-15-9-10-16(30-15)27-14-8-4-2-6-12(14)18(22(27)21(17)26)20(19)24(29)25-23/h1-8,15-16H,9-10H2,(H,25,28,29show more
    Sinónimos
    EX-A4201 | HMS3229O08 | J-006782 | AKOS024457167 | S6U3J3UP11 | NCGC00167774-01 | SB218078 | SB-218078 | (15S,18R)-28...
  2. OF 1, bromodomain and PHD finger containing 1;bromodomain and PHD finger containing 3
    CAS: 919973-83-4 Número CE: 809-510-5 Fórmula: C17H18BrN3O4S Peso molecular: 440.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: O286836
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    Nome IUPAC
    4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxobenzimidazol-5-yl)-2-methylbenzenesulfonamide
    SMILES
    CC1=C(C=CC(=C1)Br)S(=O)(=O)NC2=CC3=C(C=C2OC)N(C(=O)N3C)C
    InChIKey
    YUNQZQREIHWDQT-UHFFFAOYSA-N
    InChI
    1S/C17H18BrN3O4S/c1-10-7-11(18)5-6-16(10)26(23,24)19-12-8-13-14(9-15(12)25-4)21(3)17(22)20(13)2/h5-9,19H,1-4H3
    Sinónimos
    OF-1, >=98% (HPLC) | 9,10-Anthraguinone | AKOS000481248 | EX-A2269 | A16000 | NCGC00384195-05 | GTPL9523 | 4-bromo-N-...
  3. OG-L002, Inhibitor of lysine demethylase 1A
    CAS: 1357302-64-7 Fórmula: C15H15NO Peso molecular: 225.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: O288423
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    Nome IUPAC
    3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol
    SMILES
    C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O
    InChIKey
    DSOJSZXQRJGBCW-CABCVRRESA-N
    InChI
    1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1
    Sinónimos
    4'-((1R,2S)-2-aminocyclopropyl)biphenyl-3-ol | 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol | 4′-((1R,2S)-2-Aminocy...
  4. OICR 9429, Inhibitor of WD repeat domain 5
    CAS: 1801787-56-3 Fórmula: C29H32F3N5O3 Peso molecular: 555.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: O287472
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    Identificadores técnicos
    Nome IUPAC
    N-[2-(4-methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1H-pyridine-3-carboxamide
    SMILES
    CN1CCN(CC1)C2=C(C=C(C=C2)C3=CC=CC(=C3)CN4CCOCC4)NC(=O)C5=CNC(=O)C=C5C(F)(F)F
    InChIKey
    DJOVLOYCGXNVPI-UHFFFAOYSA-N
    InChI
    1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15show more
    Sinónimos
    N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine...
  5. SNS-314 Mesylate
    CAS: 1146618-41-8 PubChem CID: 24995523 Fórmula: C18H15ClN6OS2.CH4O3S Peso molecular: 527.04
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: S128045
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    Nome IUPAC
    1-(3-chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea;methanesulfonic acid
    SMILES
    CS(=O)(=O)O.C1=CC(=CC(=C1)Cl)NC(=O)NC2=NC=C(S2)CCNC3=NC=NC4=C3SC=C4
    InChIKey
    FYCODPVDEFFWSR-UHFFFAOYSA-N
    InChI
    1S/C18H15ClN6OS2.CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16;1-5(2,3)4/h1-3,5,7-10H,4,6H2,(H,20,22,show more
    Sinónimos
    BCP24792 | HMS3654A12 | MLS006011040 | SCHEMBL17257952 | N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamin...
  6. OTX015, Bromodomain and extra-terminal motif (BET) inhibitor
    CAS: 202590-98-5 Fórmula: C25H22ClN5O2S Peso molecular: 491.99
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: O125058
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    Nome IUPAC
    2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]-N-(4-hydroxyphenyl)acetamshow more
    SMILES
    CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C
    InChIKey
    GNMUEVRJHCWKTO-FQEVSTJZSA-N
    InChI
    1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,show more
    Sinónimos
    OTX 015 | OTX-015 | 2-((6S)-4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-6H-THIENO(3,2- F)(1,2,4)TRIAZOLO(4,3-A)(1,4)DIAZEPIN-6...
  7. OUL35
    CAS: 6336-34-1 Fórmula: C14H12N2O3 Peso molecular: 256.26
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: O288317
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    Identificadores técnicos
    Nome IUPAC
    4-(4-carbamoylphenoxy)benzamide
    SMILES
    C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)N
    InChIKey
    XZRCQWLPMXFGHE-UHFFFAOYSA-N
    InChI
    1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)
    Sinónimos
    NSC39047 | HMS2754A23 | OUL 35 | NSC39047 | NSC-39047 | SR-01000391101-1 | AKOS001482413 | DTXSID10284793 | SCHEMBL31...
  8. SRT 1460
    CAS: 925432-73-1 PubChem CID: 24180124 Fórmula: C26H29N5O4S Peso molecular: 507.62
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: S334321
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    Identificadores técnicos
    Nome IUPAC
    3,4,5-trimethoxy-N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]benzamide
    SMILES
    COC1=CC(=CC(=C1OC)OC)C(=O)NC2=CC=CC=C2C3=CN4C(=CSC4=N3)CN5CCNCC5
    InChIKey
    SBEWVVLMFLTQFE-UHFFFAOYSA-N
    InChI
    1S/C26H29N5O4S/c1-33-22-12-17(13-23(34-2)24(22)35-3)25(32)28-20-7-5-4-6-19(20)21-15-31-18(16-36-26(31)29-21)14-30-10-8-27-9-11-30/h4-7,12-13,15-16,27Hshow more
    Sinónimos
    BRD-K20979596-019-01-6 | MFCD19053214 | SCHEMBL1302286 | 3,4,5-Trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-...
  9. Olaparib (AZD2281, Ku-0059436), PARP 1, 2 and 3 inhibitor
    CAS: 763113-22-0 Número CE: 642-941-5 Fórmula: C24H23FN4O3 Peso molecular: 434.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: O126162
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    Nome IUPAC
    4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
    SMILES
    C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
    InChIKey
    FDLYAMZZIXQODN-UHFFFAOYSA-N
    InChI
    1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,2show more
    Sinónimos
    KU-0059436 | KU0059436 | KU-0059436 | 4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1...
  10. Salermida
    CAS: 1105698-15-4 PubChem CID: 135659046 Fórmula: C26H22N2O2 Peso molecular: 394.47
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: S287227
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    Nome IUPAC
    N-[3-[(2-hydroxynaphthalen-1-yl)methylideneamino]phenyl]-2-phenylpropanamide
    SMILES
    CC(C1=CC=CC=C1)C(=O)NC2=CC(=CC=C2)N=CC3=C(C=CC4=CC=CC=C43)O
    InChIKey
    HQSSEGBEYORUBY-UHFFFAOYSA-N
    InChI
    1S/C26H22N2O2/c1-18(19-8-3-2-4-9-19)26(30)28-22-12-7-11-21(16-22)27-17-24-23-13-6-5-10-20(23)14-15-25(24)29/h2-18,29H,1H3,(H,28,30)
    Sinónimos
    BDBM50309827 | (E)-N-(3-((2-hydroxynaphthalen-1-yl)methyleneamino)phenyl)-2-phenylpropanamide | SCHEMBL8103931 | EX-A...
  11. Butyric acid
    CAS: 107-92-6 Número CE: 203-532-3 Fórmula: C4H8O2 Peso molecular: 88.11
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99.5%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: B110442
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    Identificadores técnicos
    Nome IUPAC
    butanoic acid
    SMILES
    CCCC(=O)O
    InChIKey
    FERIUCNNQQJTOY-UHFFFAOYSA-N
    InChI
    1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
    Sinónimos
    GTPL1059 | butoic acid | Honey robber | propylformic acid | Tox21_300164 | BUTYRIC ACID [WHO-DD] | 1-propanecarboxyla...
  12. Butyric acid
    CAS: 107-92-6 Número CE: 203-532-3 Fórmula: C4H8O2 Peso molecular: 88.11
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: B274612
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    Identificadores técnicos
    Nome IUPAC
    butanoic acid
    SMILES
    CCCC(=O)O
    InChIKey
    FERIUCNNQQJTOY-UHFFFAOYSA-N
    InChI
    1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
    Sinónimos
    GTPL1059 | butoic acid | Honey robber | propylformic acid | Tox21_300164 | BUTYRIC ACID [WHO-DD] | 1-propanecarboxyla...
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Perguntas frequentes

What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which Epigenetics subcategory should I start with?
Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering Epigenetics?
Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Epigenetics by structure or CAS number?
Yes. Within Epigenetics you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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