Epigenética

Explore compostos orientados para vias metabólicas destinados à investigação em epigenética, incluindo ferramentas relevantes para a regulação da cromatina e o controlo transcricional. Utilize esta página para comparar moléculas utilizadas em fluxos de trabalho de validação de alvos, estudos de mecanismos e modulação do estado celular.

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  1. Nexturastat A, Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 6
    CAS: 1403783-31-2 Fórmula: C19H23N3O3 Peso molecular: 341.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: N349054
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    Nome IUPAC
    4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide
    SMILES
    CCCCN(CC1=CC=C(C=C1)C(=O)NO)C(=O)NC2=CC=CC=C2
    InChIKey
    JZWXMCPARMXZQV-UHFFFAOYSA-N
    InChI
    1S/C19H23N3O3/c1-2-3-13-22(19(24)20-17-7-5-4-6-8-17)14-15-9-11-16(12-10-15)18(23)21-25/h4-12,25H,2-3,13-14H2,1H3,(H,20,24)(H,21,23)
    Sinónimos
    MFCD28099804 | AKOS026750221 | Nexturastat A | Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy- | ...
  2. SBC 0946, Inhibitor of DOT1 like histone lysine methyltransferase
    CAS: 1561178-17-3 Número CE: 808-588-8 PubChem CID: 56962337 Fórmula: C28H40BrN7O4 Peso molecular: 618.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: S286970
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    Nome IUPAC
    1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urshow more
    SMILES
    CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=C(C4=C(N=CN=C43)N)Br)O)O
    InChIKey
    IQCKJUKAQJINMK-HUBRGWSESA-N
    InChI
    1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,1show more
    Sinónimos
    1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihidroxitetrahidrofurano-2-il)metil)(i...
  3. PARPi-FL
    CAS: 1380359-84-1 PubChem CID: 70697686 Fórmula: C34H32BF3N6O3 Peso molecular: 640.46
    Solid ≥98%
    ◐ .Sob encomenda · 8–12 semanas Item #: P286654
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    Nome IUPAC
    4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanoyl]piperazine-1-carbonyl]show more
    SMILES
    [B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F)C)C)(F)F
    InChIKey
    IGUTVNUEFKPBGK-UHFFFAOYSA-N
    InChI
    1S/C34H32BF3N6O3/c1-21-17-22(2)43-31(21)20-25-9-8-24(44(25)35(43,37)38)10-12-32(45)41-13-15-42(16-14-41)34(47)28-18-23(7-11-29(28)36)19-30-26-5-3-4-6-show more
    Sinónimos
    Boron, (4-((3-((4-(3-(5-((3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)methyl)-1H-pyrrol-2-yl-kappaN)-1-oxopropyl)-1-piper...
  4. Nudifloramide-d3
    CAS: 1207384-48-2 Fórmula: C7H5D3N2O2 Peso molecular: 155.17
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: N349303
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    Nome IUPAC
    6-oxo-1-(trideuteriomethyl)pyridine-3-carboxamide
    SMILES
    CN1C=C(C=CC1=O)C(=O)N
    InChIKey
    JLQSXXWTCJPCBC-FIBGUPNXSA-N
    InChI
    1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)/i1D3
    Sinónimos
    CHEBI:145118 | 1-(~2~H_3_)Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide | 6-Oxo-1-(trideuteriomethyl)pyridine-3-carb...
  5. Resveratrol, Inhibitor of COX-2;Agonist of TAS2R14;Antagonist of Peroxisome proliferator-activated receptor-γ
    CAS: 501-36-0 Número CE: 610-504-8 Fórmula: C14H12O3 Peso molecular: 228.24
    Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: R107314
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    Nome IUPAC
    5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
    SMILES
    C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O
    InChIKey
    LUKBXSAWLPMMSZ-OWOJBTEDSA-N
    InChI
    1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
    Sinónimos
    Q369O8926L | CHEBI:27881 | CU-01000001503-3 | HMS1792H15 | NSC133100 | BPBio1_000479 | NCGC00344093-09 | RESVERATROL ...
  6. UCN-01, Inhibitor of 3-phosphoinositide dependent protein kinase 1;Inhibitor of checkpoint kinase 1;Inhibitor of checkpoint kinase 2;Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of LCK proto-oncogene; Src family ty
    CAS: 112953-11-4 PubChem CID: 72271 Fórmula: C28H26N4O4 Peso molecular: 482.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%(HPLC)
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: U138038
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    Nome IUPAC
    (2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8show more
    SMILES
    CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(NC6=O)O)NC)OC
    InChIKey
    PBCZSGKMGDDXIJ-HQCWYSJUSA-N
    InChI
    1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,show more
    Sinónimos
    BDBM17054 | NSC638850 | NSC-638850 | 7-Hydroxystaurosporine [WHO-DD] | KRX0601 | KRX-0601 | Dietilamina | Isocyanic a...
  7. TX-1123
    CAS: 157397-06-3 PubChem CID: 403661 Fórmula: C20H24O3 Peso molecular: 312.4
    ◐ .Sob encomenda · 8–12 semanas Item #: T339226
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    Nome IUPAC
    2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione
    SMILES
    CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O
    InChIKey
    VUEUMQIBGLKJJD-UHFFFAOYSA-N
    InChI
    1S/C20H24O3/c1-19(2,3)14-10-12(9-13-16(21)7-8-17(13)22)11-15(18(14)23)20(4,5)6/h7-11,23H,1-6H3
    Sinónimos
    2-((3,5-di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione
  8. MK-8745
    CAS: 885325-71-3 Fórmula: C20H19ClFN5OS Peso molecular: 431.91
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: M333437
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    Nome IUPAC
    (3-chloro-2-fluorophenyl)-[4-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]piperazin-1-yl]methanone
    SMILES
    C1CN(CCN1CC2=NC(=CC=C2)NC3=NC=CS3)C(=O)C4=C(C(=CC=C4)Cl)F
    InChIKey
    YCRFPWKUUNKNDN-UHFFFAOYSA-N
    InChI
    1S/C20H19ClFN5OS/c21-16-5-2-4-15(18(16)22)19(28)27-10-8-26(9-11-27)13-14-3-1-6-17(24-14)25-20-23-7-12-29-20/h1-7,12H,8-11,13H2,(H,23,24,25)
    Sinónimos
    (3-Chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-methanone | 1-(3-Chloro-2-fluor...
  9. Marein
    CAS: 535-96-6 PubChem CID: 6441269 Fórmula: C21H22O11 Peso molecular: 450.39
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: M342001
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    Nome IUPAC
    (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one
    SMILES
    O=C(C1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C(O)=C1O)/C=C/C3=CC=C(O)C(O)=C3
    InChIKey
    XGEYXJDOVMEJNG-HTFDPZBKSA-N
    InChI
    1S/C21H22O11/c22-8-15-18(28)19(29)20(30)21(32-15)31-14-6-3-10(16(26)17(14)27)11(23)4-1-9-2-5-12(24)13(25)7-9/h1-7,15,18-22,24-30H,8H2/b4-1+/t15-,18-,1show more
    Sinónimos
    (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypheny...
  10. GSK-J2
    CAS: 1394854-52-4 Fórmula: C22H23N5O2 Peso molecular: 389.4
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: G275564
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    Nome IUPAC
    3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid
    SMILES
    C1CN(CCC2=CC=CC=C21)C3=NC(=NC(=C3)NCCC(=O)O)C4=CN=CC=C4
    InChIKey
    LJIFOCRGDDQFJF-UHFFFAOYSA-N
    InChI
    1S/C22H23N5O2/c28-21(29)7-11-24-19-14-20(26-22(25-19)18-6-3-10-23-15-18)27-12-8-16-4-1-2-5-17(16)9-13-27/h1-6,10,14-15H,7-9,11-13H2,(H,28,29)(H,24,25,show more
    Sinónimos
    3-[[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid | BCP08263 | SCHEMBL1...
  11. Garcinol, Inhibitor of E1A binding protein p300;Inhibitor of lysine acetyltransferase 2B
    CAS: 78824-30-3 Fórmula: C38H50O6 Peso molecular: 602.8
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: G275583
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    Nome IUPAC
    (1S,3Z,5R,7R)-3-[(3,4-dihydroxyphenyl)-hydroxymethylidene]-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)-1-[(2S)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]bicyclshow more
    SMILES
    CC(=CCC1CC2(C(=O)C(=C(C3=CC(=C(C=C3)O)O)O)C(=O)C(C2=O)(C1(C)C)CC=C(C)C)CC(CC=C(C)C)C(=C)C)C
    InChIKey
    DTTONLKLWRTCAB-BZSUNBQASA-N
    InChI
    1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-1show more
    Sinónimos
    Garcinol | CHEBI:5276 | MFCD03700761 | (1R,5R,7R)-3-(3,4-Dihydroxybenzyol)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-...
  12. GSK-J4, Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C;Inhibitor of lysine demethylase 6A;Inhibitor of lysine demethylase 6B
    CAS: 1373423-53-0 Fórmula: C24H27N5O2 Peso molecular: 417.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: G276086
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    Nome IUPAC
    ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate
    SMILES
    CCOC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=CC=CC=C4CC3
    InChIKey
    WBKCKEHGXNWYMO-UHFFFAOYSA-N
    InChI
    1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9,13,17H,2,10-12,14-16H2,1H3,(H,26,2show more
    Sinónimos
    MFCD22683852 | Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoate |...
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Perguntas frequentes

What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which Epigenetics subcategory should I start with?
Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering Epigenetics?
Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Epigenetics by structure or CAS number?
Yes. Within Epigenetics you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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