MUC1 Mouse mAb - Primary antibody, specific to MUC1, Mouse IgG1

Cat. No.: Ab116370

GRAU & PUREZA Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA

Application

WB

Host species

Mouse

Reactive species

Human

Isotype

Mouse IgG1

Clone Number

C1

Conjugation

Unconjugated

Visão geral

Mouse anti Human MUC1 antibody; , Monoclonal (C1), could be used for WB and so on.
Application:
WB: 0.01-2 µg/mL
Protein Function
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Especificações

Product Name

MUC1 Mouse mAb - Primary antibody, specific to MUC1, Mouse IgG1

Sinónimos

ADMCKD antibody | ADMCKD1 antibody | Breast carcinoma associated antigen DF3 antibody | Breast carcinoma-associated antigen DF3 antibody | CA 15-3 antibody | CA15 3 antibody | CA15 3 antigen antibody | CA15-3 antibody | CA15.3 antibody | Cancer antigen 15

Especificações e pureza

Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA

Espécie hospedeira

Mouse

Especificidade

MUC1

Imunogénio

Recombinant MUC1 expressed in E.coli (AA 1034~1151)

Controlo positivo

WB: Human milk.

Conjugação

Unconjugated

Grau

Azide Free, Carrier Free, ExactAb™, High Performance, Validated

Isótipo

Mouse IgG1

Tipo de corrente de luz

kappa

SDS-PAGE

150 kDa

Método de purificação

Protein A + Protein G affinity purified

Concentração

See COA

Product Line

Produtos biológicos

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -20°C,Avoid repeated freezing and thawing

Enviado em

Ice chest + Ice pads

Estabilidade e armazenamento

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

Western Blot: MUC1 Mouse mAb (Ab116370)

MUC1 Mouse mAb (Ab116370) - Western Blot
All lanes: MUC1 Mouse mAb (Ab116370) at 1/3000 dilution
Samples: Human milk
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 25 kDa
Observed band size: 23,19 kDa
Exposure time: 10.0 s

Aplicação

Aplicação

Dilution info

WB

0.01-2 µg/mL

Alvos associados (humanos)

MUC1 Tchem Mucin-1 (0 Activities)

Discover Target: MUC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Perguntas frequentes

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (MUC1 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.