Recombinant p21 Antibody - Primary antibody, specific to p21, Mouse IgG2a

Cat. No.: Ab119617
Disponível para encomenda
GRADE & PURITY Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. 2.4 mg/mL
Application
IHC
Host species
Mouse
Reactive species
Human
Isotype
Mouse IgG2a
Clone Number
MyM1-p21
Conjugation
Unconjugated
★
Size
Alemanha (EU)
USA*
Price
Qty
10μl
Ab119617-10μl
—
5 Em stock
86,69€
50μl
Ab119617-50μl
—
2 Em stock
225,53€
100μl
Ab119617-100μl
Sob encomenda · 8–12 semanas
364,36€
1ml
Ab119617-1ml
Sob encomenda · 8–12 semanas
1735,39€
Enter a quantity for the sizes you want to add.
🧪

Why this grade

ExactAb™, Validated, Recombinant, 2.4 mg/mL ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Avoid repeated freezing and thawing Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Mouse anti Human p21 Antibody, Recombinant (MyM1-p21), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Specifications

Product Name
Recombinant p21 Antibody - Primary antibody, specific to p21, Mouse IgG2a
Sinónimos
CAP20 antibody | CDK-interacting protein 1 antibody | CDKI antibody | CDKN1 antibody | Cdkn1a antibody | CDN1A_HUMAN antibody | CIP1 antibody | Cyclin Dependent Kinase Inhibitor 1A antibody | Cyclin-dependent kinase inhibitor 1 antibody | Cyclin-dependent
Especificações e pureza
ExactAb™, Validated, Recombinant, 2.4 mg/mL
Espécie hospedeira
Mouse
Especificidade
p21
Controlo positivo
IHC: Human tonsil and breast cancer tissues.
Conjugação
Unconjugated
Grau
ExactAb™, Recombinant, Validated
Isótipo
Mouse IgG2a
Tipo de corrente de luz
kappa
SDS-PAGE
150 kDa
Método de purificação
Protein A purified
Concentração
2.4 mg/mL
Armazenamento e envio
Forma
Liquid
Condições de armazenamento de armazenamento
Store at 2-8°C,Avoid repeated freezing and thawing
Enviado em
Wet ice
Estabilidade e armazenamento
Store at 2-8°C long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imagens

Recombinant p21 Antibody (Ab119617) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Recombinant p21 Antibody (Ab119617) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Aplicação
AplicaçãoDilution info
IHC

1/100 - 1/200

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Alvos associados (humanos)
CDKN1A Tchem Cyclin-dependent kinase inhibitor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CDKN1A Tchem CDK-interacting protein 1 (92 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDataItem
ZJ24F0404783Certificate of AnalysisApr 23, 2024 Ab119617
ZJ24F0404782Certificate of AnalysisApr 23, 2024 Ab119617
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Perguntas frequentes

What does ExactAb? mean?
ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.
What does Recombinant mean?
Recombinant is a defined analytical purity tier suitable for workflows requiring a specific validated property. It specifies a minimum assay percentage, controlled limits on common impurities (water, heavy metals, residue on ignition), and lot-to-lot consistency. Recombinant is one of several purity tiers — choose based on the sensitivity and regulatory requirements of your method.
How should this product be stored?
Store at 2–8 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Which species reactivity has this antibody been validated against?
Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Recombinant p21 Antibody); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide →

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