Recombinant p38 alpha/MAPK14 Antibody - Primary antibody, specific to p38 alpha/MAPK14, Rabbit IgG

Cat. No.: Ab119717

GRADE & PURITY Recombinant, Validated, ExactAb™, High Performance, See COA

Application

WB

Host species

Rabbit

Reactive species

Hamster, Human, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Visão geral

Rabbit anti Human p38 alpha/MAPK14 Antibody, Recombinant, could be used for WB and so on.

Specifications

Product Name

Recombinant p38 alpha/MAPK14 Antibody - Primary antibody, specific to p38 alpha/MAPK14, Rabbit IgG

Sinónimos

CSAID-binding protein antibody | Csaids binding protein antibody | CSBP antibody | CSBP1 antibody | CSBP2 antibody | CSPB1 antibody | Cytokine suppressive anti-inflammatory drug-binding protein antibody | EXIP antibody | MAP kinase 14 antibody | MAP kinas

Especificações e pureza

Recombinant, ExactAb™, Validated, High Performance, See COA

Mecanismos bioquímicos e fisiológicos

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proi

Espécie hospedeira

Rabbit

Especificidade

p38 alpha/MAPK14

Imunogénio

A synthetic peptide of human p38 (AA 337-355).

Controlo positivo

WB: HeLa, Jurkat, MCF7 and HEK293 cell lysates.

Conjugação

Unconjugated

Grau

ExactAb™, High Performance, Recombinant, Validated

Isótipo

Rabbit IgG

Tipo de corrente de luz

kappa

SDS-PAGE

150 kDa

Método de purificação

Protein A purified

Concentração

See COA

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -20°C,Avoid repeated freezing and thawing

Enviado em

Ice chest + Ice pads

Estabilidade e armazenamento

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

Western Blot: Recombinant p38 alpha/MAPK14 Antibody (Ab119717)

Recombinant p38 alpha/MAPK14 Antibody (Ab119717) - Western Blot
All lanes: Recombinant p38 alpha/MAPK14 Antibody (Ab119717) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 41 kDa
Observed band size: 41 kDa
Exposure time: 60.5 s

Aplicação

• Aplicação: Dilution info
• WB:

  1/1000 - 1/5000 ;

Alvos associados (humanos)

MAPK14 Tchem Mitogen-activated protein kinase 14 (0 Activities)

Discover Target: MAPK14

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Referências

1. Peng Zhu, Jianqiang Qian, Zhongyuan Xu, Chi Meng, Ji Liu, Wenpei Shan, Weizhong Zhu, Yongjun Wang, Yumin Yang, Wei Zhang, Yanan Zhang, Yong Ling.  (2020)  Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling.  JOURNAL OF NATURAL PRODUCTS,      [PMID:33026807] [10.1021/acs.jnatprod.0c00599]