Uliledlimab (anti-CD73) - Primary antibody, specific to NT5E, >95% (SDS-PAGE&SEC), Human IgG1

CAS: 2378407-27-1 Cat. No.: Ab182937

GRADE & PURITY Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Human

Reactive species

Cynomolgus monkey, Human

Isotype

Human IgG1

Conjugation

Unconjugated

Visão geral

Uliledlimab (anti-CD73) is a potent against CD73 humanized monoclonal antibody. Uliledlimab (anti-CD73) inhibits the conversion of extracellular adenosine monophosphate (AMP) to adenosine. Uliledlimab (anti-CD73) can be used in research of cancer​.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name

Uliledlimab (anti-CD73) - Primary antibody, specific to NT5E, >95% (SDS-PAGE&SEC), Human IgG1

Sinónimos

5' NT antibody | 5' nucleotidase (CD73) antibody | 5' nucleotidase precursor antibody | 5' nucleotidase, ecto antibody | 5' nucleotidase, ecto (CD73) antibody | 5'-NT antibody | 5'-nucleotidase antibody | 5NTD_HUMAN antibody | CD73 antibody | CD73 antigen

Especificações e pureza

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Espécie hospedeira

Human

Especificidade

NT5E

Conjugação

Unconjugated

Grau

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Isótipo

Human IgG1

Tipo de corrente de luz

kappa

SDS-PAGE

26.6 kDa (Light Chain) & 53.7 kDa (Heavy Chain), under reducing conditions; 197.8 kDa, under non-reducing conditions.

Método de purificação

Protein A purified

Pureza

>95% (SDS-PAGE&SEC)

Concentração

See COA

CAS

2378407-27-1

Product Line

Produtos biológicos

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -80°C,Avoid repeated freezing and thawing

Enviado em

Dry ice packs + Cold packs

Estabilidade e armazenamento

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

Flow Cytometry: Uliledlimab (anti-CD73) (Ab182937)

Uliledlimab (anti-CD73) (Ab182937) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling CD73 (red) with Uliledlimab (anti-CD73) (Ab182937). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Uliledlimab (anti-CD73) (Ab182937)

Uliledlimab (anti-CD73) (Ab182937) - ELISA
Immobilized human CD73-his tag at 2.0 μg/mL can bind Uliledlimab (anti-CD73) (Ab182937) with the EC50 is 58.13 μg/mL.

SEC: Uliledlimab (anti-CD73) (Ab182937)

Uliledlimab (anti-CD73) (Ab182937) - SEC
The purity of Uliledlimab (anti-CD73) (Ab182937) is more than 95% verified by HPLC.

Alvos associados (humanos)

NT5E Tchem 5'-nucleotidase (0 Activities)

Discover Target: NT5E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Perguntas frequentes

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2378407-27-1.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Uliledlimab (anti-CD73)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.