1-Hydroxypyridine-2-thione zinc salt - Moligand™, ≥96% , Activator of K v7.1;Activator of K v7.2;Activator of K v7.4;Activator of K v7.5, CAS No.13463-41-7, Activator of K v7.1;Activator of K v7.2;Activator of K v7.4;Activator of K v7.5

CAS: 13463-41-7 Cat. No.: H122405 Peso molecular: 317.7 Número EC: 236-671-3

GRADE & PURITY Moligand™, ≥96%

Synonyms

2-Mercaptopyridine N-Oxide Zinc Salt | Bis(2-pyridylthio) Zinc 1,1'-Dioxide | 2-Pyridinethiol 1-Oxide Zinc Salt | Zinc Pyrithione

Storage

Room temperature

Shipped In

Normal

Specifications

Sinónimos

2-Mercaptopyridine N-Oxide Zinc Salt | Bis(2-pyridylthio) Zinc 1, 1'-Dioxide | 2-Pyridinethiol 1-Oxide Zinc Salt | Zinc Pyrithione

Especificaciones y pureza

Moligand™, ≥96%

Mecanismos bioquímicos y fisiológicos

Antibiotic agent. Potent K V 7 channel activator. Augments KCNQ1, -2, -4, and 5 channel currents. Fungal membrane transport inhibitor. Shows fungistatic and bacteriostatic effects in vivo.

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Grado

Moligand™

Tipo de acción

ACTIVATOR

Mecanismo de acción

Activator of K v7.1;Activator of K v7.2;Activator of K v7.4;Activator of K v7.5

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥96%

Nombres e identificadores

• WGK Alemania: 3
• RTECS: ZH0950000
• Número ONU: 2811
• Grupo de embalaje: I
• Peso molecular: 317.7

Objetivos asociados (humanos)

KCNQ4 Tclin Potassium voltage-gated channel subfamily KQT member 4 (1 Activities)

Discover Target: KCNQ4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNQ5 Tclin Potassium voltage-gated channel subfamily KQT member 5 (1 Activities)

Discover Target: KCNQ5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNQ2 Tclin Potassium voltage-gated channel subfamily KQT member 2 (1 Activities)

Discover Target: KCNQ2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNQ1 Tclin Potassium voltage-gated channel subfamily KQT member 1 (1 Activities)

Discover Target: KCNQ1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Solubilidad: Solubility in Pyridine almost transparency

Referencias

1. Shu Zhou, Shukai Liu, Xiao Meng, Tianqi Liu, Xiaoyong Shi, Rongguo Su.  (2024)  Indirect photodegradation of zinc pyrithione: The effect of chromophoric dissolved organic matter components and seawater factors.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2024.112421]