Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Sonrisas canónicas | CN(C(=N)N[N+](=O)[O-])N=O |
|---|---|
| IUPAC Name | 1-methyl-3-nitro-1-nitrosoguanidine |
| InChIKey | VZUNGTLZRAYYDE-UHFFFAOYSA-N |
| INCHI | 1S/C2H5N5O3/c1-6(5-8)2(3)4-7(9)10/h1H3,(H2,3,4) |
| Isómeros SMILES | CN(C(=N)N[N+](=O)[O-])N=O |
| WGK Alemania | 3 |
| RTECS | MF4200000 |
| Número ONU | 1325 |
| Grupo de embalaje | II |
| Peso molecular | 147.09 |
| Beilstein | 1779490 |
| Reaxy-Rn | 1779490 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1779490&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic nitrogen compounds |
| Clase | Organonitrogen compounds |
| Subclass | Guanidines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Nitroguanidines |
| Alternative Parents | Nitramines Organic N-nitroso compounds Organopnictogen compounds Organic zwitterions Organic oxides Imines Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Nitroguanidine - Nitramine - Organic n-nitroso compound - Organic nitro compound - Organic nitroso compound - Organic 1,3-dipolar compound - Allyl-type 1,3-dipolar organic compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic zwitterion - Imine - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as nitroguanidines. These are organonitrogen compounds containing a nitro group, which is N-linked to a guanidine. |
| External Descriptors | nitroso compound |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | May 26, 2026 | M105583 | |
| Certificate of Analysis | May 26, 2026 | M105583 | |
| Certificate of Analysis | Dec 22, 2025 | M105583 | |
| Certificate of Analysis | Dec 22, 2025 | M105583 | |
| Certificate of Analysis | Dec 22, 2025 | M105583 | |
| Certificate of Analysis | Dec 22, 2025 | M105583 | |
| Certificate of Analysis | Dec 22, 2025 | M105583 | |
| Certificate of Analysis | Apr 19, 2025 | M105583 | |
| Certificate of Analysis | Apr 19, 2025 | M105583 | |
| Certificate of Analysis | Apr 19, 2025 | M105583 | |
| Certificate of Analysis | Dec 10, 2024 | M105583 | |
| Certificate of Analysis | Dec 10, 2024 | M105583 | |
| Certificate of Analysis | Dec 10, 2024 | M105583 | |
| Certificate of Analysis | Apr 28, 2024 | M105583 | |
| Certificate of Analysis | Apr 28, 2024 | M105583 | |
| Certificate of Analysis | Apr 28, 2024 | M105583 | |
| Certificate of Analysis | Apr 28, 2024 | M105583 | |
| Certificate of Analysis | Apr 28, 2024 | M105583 | |
| Certificate of Analysis | Apr 28, 2024 | M105583 | |
| Certificate of Analysis | Dec 13, 2023 | M105583 | |
| Certificate of Analysis | Dec 13, 2023 | M105583 | |
| Certificate of Analysis | Dec 13, 2023 | M105583 | |
| Certificate of Analysis | Aug 03, 2023 | M105583 | |
| Certificate of Analysis | Aug 03, 2023 | M105583 | |
| Certificate of Analysis | Aug 03, 2023 | M105583 | |
| Certificate of Analysis | Jan 09, 2023 | M105583 | |
| Certificate of Analysis | Jan 09, 2023 | M105583 | |
| Certificate of Analysis | Jan 09, 2023 | M105583 |
| Sensibilidad | Heat & Light & Moisture sensitive |
|---|---|
| Punto de fusión (°C) | 118°C |
| Peso molecular | 147.090 g/mol |
| XLogP3 | 0.100 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 147.039 Da |
| Monoisotopic Mass | 147.039 Da |
| Topological Polar Surface Area | 114.000 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 161.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yanning Zhu, Ruyun Ma, Wen Cheng, Mengyao Qin, Weiheng Guo, Ying Qi, Jianye Dai. (2023) Sijunzi decoction ameliorates gastric precancerous lesions via regulating oxidative phosphorylation based on proteomics and metabolomics. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:37467821] [10.1016/j.jep.2023.116925] |
| 2. Yi Zhirong, Jia Qingling, Wang Yujiao, Zhang Yuqin, Xie Tianyi, Ling Jianghong. (2023) Elian granules alleviate precancerous lesions of gastric cancer in rats by suppressing M2-type polarization of tumor-associated macrophages through NF-κB signaling pathway. BMC Complementary Medicine and Therapies, 23 (1): (1-11). [PMID:37291549] [10.1186/s12906-023-04015-7] |
| 3. Zhenyuan Wang, Guangxing Pan, Binshen Wang, Ling Zhang, Weiwei Zhao, Xing Ma, Jichuan Zhang, Jiaheng Zhang. (2019) Synthesis and Properties of Azide-Functionalized Ionic Liquids as Attractive Hypergolic Fuels. Chemistry-An Asian Journal, 14 (12): (2122-2128). [PMID:30950213] [10.1002/asia.201900364] |
| 4. Jia Liu, Mengyu Li, Guobao Chen, Junhui Yang, Ying Jiang, Fang Li, Haibing Hua. (2024) Jianwei Xiaoyan granule ameliorates chronic atrophic gastritis by regulating HIF-1α-VEGF pathway. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:39025161] [10.1016/j.jep.2024.118591] |
| 5. Yuxi Guo, Xuemei Jia, Pengli Du, Jie Wang, Yao Du, Bolin Li, Yucong Xue, Jianming Jiang, Yanru Cai, Qian Yang. (2023) Mechanistic insights into the ameliorative effects of Xianglianhuazhuo formula on chronic atrophic gastritis through ferroptosis mediated by YY1/miR-320a/TFRC signal pathway. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:38158098] [10.1016/j.jep.2023.117608] |
| 6. Suizhi Cheng, Li Che, Qingqing Yang, Rongjing Sun, Yuhong Nie, Haoyue Shi, Yiwen Ding, Li Wang, Zuo Du, Zhenzhong Liu. (2022) Folic acid ameliorates N-methyl-N′-nitro-N-nitrosoguanidine-induced esophageal inflammation via modulation of the NF-κB pathway. TOXICOLOGY AND APPLIED PHARMACOLOGY, [PMID:35643124] [10.1016/j.taap.2022.116087] |
| 7. Tong Yuling, Liu Liping, Wang Ruilin, Yang Tao, Wen Jianxia, Wei Shizhang, Jing Manyi, Zou Wenjun, Zhao Yanling. (2021) Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism. Frontiers in Pharmacology, [PMID:33841162] [10.3389/fphar.2021.644638] |
| 8. Yuling Tong, Ruilin Wang, Xia Liu, Miao Tian, Yanling Wang, Yanfei Cui, Wenjun Zou, Yanling Zhao. (2021) Zuojin Pill ameliorates chronic atrophic gastritis induced by MNNG through TGF-β1/PI3K/Akt axis. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:33524511] [10.1016/j.jep.2021.113893] |
| 9. Guang-Gang Gao, Guo-Biao Xu, Jin-Lian Li, Ji-Wen Cui, Dong-Mei Wu, Hong-Bin Qiu. (2014) Low-level expression of purine bases in BALB/3T3 cells monitored by ultrasensitive graphene-based glass carbon electrode. ANALYTICAL BIOCHEMISTRY, [PMID:25205651] [10.1016/j.ab.2014.08.034] |
| 10. Chaoqun Fei, Shulan Qi, Jiahuan Zhang, Shi Zhou, Yingxue Guo, Yanli Zhao, Jiazheng Jin, Jinlian Li, Ximing Cui, Dongmei Wu. (2024) Electrochemical voltammetry assessment of cellular DNA damage caused by drugs with different mechanisms: A comparative analysis with the γH2AX focus and alkaline comet assays. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112085] |
| 11. Qi Zhang, Ruibing Lv, Ying Wang, Zhenghang Luo, Pengyang Pan, Tingwei Wang, Quancheng Liu. (2024) Energetic copper(II) quadridentate chelate: a novel green laser-sensitive primary explosive. Inorganic Chemistry Frontiers, 11 (11): (3168-3177). [PMID:] [10.1039/D4QI00489B] |
| 12. Jiang Qianqian, Fan Guoxia, Wu Kaiwei. (2024) Potential Action Mechanism of Erianin in Relieving MNNG-triggered Chronic Atrophic Gastritis. CELL BIOCHEMISTRY AND BIOPHYSICS, [PMID:39298066] [10.1007/s12013-024-01536-x] |
| 13. Suizhi Cheng, Jin Chen, Qianhui Li, Yuhong Nie, Ting Ni, Caiting Peng, Xi Luo, Yasin Pazilat, Shumin Zhang, Jiancai Tang, Zhenzhong Liu. (2024) Protective effect of folic acid on MNNG-induced proliferation of esophageal epithelial cells via the PI3K/AKT/mTOR signaling pathway. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, [PMID:39025456] [10.1016/j.jnutbio.2024.109702] |
| 14. Qing Wang, Yefei Huang, Min Jiang, Yu Tang, Qinzhi Wang, Longlong Bai, Chenglong Yu, Xinyue Yang, Kun Ding, Weimin Wang, Jin Bai, Yansu Chen. (2024) The demethylase ALKBH5 mediates ZKSCAN3 expression through the m6A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression. JOURNAL OF HAZARDOUS MATERIALS, [PMID:38781857] [10.1016/j.jhazmat.2024.134690] |
| 15. XiaoMing Zhou, ChenXi Zhang, Wen Shen, RuiFei Zhuang, ShenLin Liu, JinDi Liu. (2025) Curzerene suppresses epithelial-mesenchymal transition in gastric precancerous lesion cells through targeted regulation of YAP via the long non-coding RNA AFAP1-AS1. PHYTOMEDICINE, [PMID:40414046] [10.1016/j.phymed.2025.156879] |
| 16. Xiao Zhang, Zhekai Huang, Xuejun Hu, Yu Tang, Xiaofeng Zhong, Li Li, Liujing Ni, Fang Li, Haibing Hua, Fangshi Zhu. (2025) Wendan Decoction ameliorates MNNG-induced chronic atrophic gastritis via the JAK2/STAT3 signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:41077317] [10.1016/j.jep.2025.120724] |
| 17. Zhenyu Luo, Yiran Xu, Yi Wang, Ningtao Cheng. (2026) Identifying active compounds and revealing integrated mechanism of phytomedicines via AI-driven chemical-biological information fusion: a case study of Weifuchun. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:] [10.1016/j.jep.2026.121598] |