Ciclo celular/Daño en el ADN

Explore moléculas pequeñas relacionadas con el control del ciclo celular y las vías de daño al ADN para la investigación oncológica, los estudios sobre puntos de control y el desarrollo de ensayos. Utilice esta categoría para comparar compuestos relevantes para el control de la proliferación, los mecanismos de reparación y la señalización de respuesta al estrés.

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  1. Ancitabine
    CAS: 31698-14-3 Formula: C9H11N3O4 Peso molecular: 225.20
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: A344981
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    Nombre IUPAC
    (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol
    SMILES
    C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N
    InChIKey
    BBDAGFIXKZCXAH-CCXZUQQUSA-N
    InChI
    1S/C9H11N3O4/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8/h1-2,4,6-8,10,13-14H,3H2/t4-,6-,7+,8-/m1/s1
    Sinónimos
    (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-6-imino-6H-furo(2',3';4,5)oxazolo(3,2-a)pyrimidine-2-methanol | 2,2'-a...
  2. Iisoindigotin
    CAS: 476-34-6 Formula: C16H10N2O2 Peso molecular: 262.26
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: I303788
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    Nombre IUPAC
    3-(2-hydroxy-1H-indol-3-yl)indol-2-one
    SMILES
    C1=CC=C2C(=C1)C(=C(N2)O)C3=C4C=CC=CC4=NC3=O
    InChIKey
    VBMISAYWIMDRCV-UHFFFAOYSA-N
    InChI
    1S/C16H10N2O2/c19-15-13(9-5-1-3-7-11(9)17-15)14-10-6-2-4-8-12(10)18-16(14)20/h1-8,17,19H
    Sinónimos
    SR-01000390554 | (3E)-3-(2-oxo-1H-indol-3-ylidene)-1H-indol-2-one | 3-(2-hydroxy-1H-indol-3-yl)indol-2-one | SCHEMBL1...
  3. GSK2850163
    CAS: 2121989-91-9 PubChem CID: 73291790 Formula: C24H29Cl2N3O Peso molecular: 446.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: G650135
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    Nombre IUPAC
    (5R)-2-[(3,4-dichlorophenyl)methyl]-N-[(4-methylphenyl)methyl]-2,7-diazaspiro[4.5]decane-7-carboxamide
    SMILES
    CC1=CC=C(C=C1)CNC(=O)N2CCCC3(C2)CCN(C3)CC4=CC(=C(C=C4)Cl)Cl
    InChIKey
    YFDASBFQKMHSSJ-XMMPIXPASA-N
    InChI
    1S/C24H29Cl2N3O/c1-18-3-5-19(6-4-18)14-27-23(30)29-11-2-9-24(17-29)10-12-28(16-24)15-20-7-8-21(25)22(26)13-20/h3-8,13H,2,9-12,14-17H2,1H3,(H,27,30)/t2show more
    Sinónimos
    (R)-2-(3,4-Dichlorobenzyl)-N-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Gsk2850163
  4. Ceramides Mixture
    CAS: 100403-19-8 Número EC: 309-560-3 PubChem CID: 74945544
    Solid ≥95%
    En Stock Articulo #: C647629
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    N-(1,3,4-trihydroxyoctadecan-2-yl)octadec-9-enamide
    SMILES
    CCCCCCCCCCCCCCC(C(C(CO)NC(=O)CCCCCCCC=CCCCCCCCC)O)O
    InChIKey
    ATGQXSBKTQANOH-UHFFFAOYSA-N
    InChI
    1S/C36H71NO4/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-35(40)37-33(32-38)36(41)34(39)30-28-26-24-22-20-16-14-12-10-8-6-4-2/h17-18,33-34,36,38-39,show more
    Sinónimos
    Ceramide 3 | SY343426 | N-[(2S,3S,4R)-1,3,4-Trihydroxy-2-octadecyl]oleamide | FT-0623551
  5. DAPI Staining Solution
    Liquid Sterile-filtered ? Sterile-filtered — passed through a 0.2µm filter to remove microorganisms. Use as a ready aseptic solution for culture and sensitive applications. BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. for Microscopy ? Microscopy grade — reagents/stains suited to sample prep and imaging. Use in microscopy where clarity and low background are needed. Suitable for Immunofluorescence(IF) ? IF grade — validated for immunofluorescence with low background staining. Use to localize targets in cells/tissue by fluorescence microscopy. 1.0 mg/mL
    En Stock Articulo #: D1372407
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    DAPI | DAPI Staining Solution | DAPI Reagent | DAPI Stain | DAPI Solution
  6. Hoechst 33342 Staining Solution
    CAS: 23491-52-3 Número EC: 245-691-1 Formula: C27H28N6O • 3HCl • xH2O Peso molecular: 561.93(anhydrous basis)
    Liquid BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. Ready-to-use ? Ready-to-use — supplied pre-formulated at working concentration, no prep needed. Use to save time and reduce pipetting/dilution errors. Biological Stain ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. for Fluorescence analysis ? Fluorescence-analysis grade — very low fluorescent impurities for clean spectra. Use in fluorescence assays where background interferes. Biological dye grade ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. for Microscopy ? Microscopy grade — reagents/stains suited to sample prep and imaging. Use in microscopy where clarity and low background are needed. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. Suitable for Immunofluorescence(IF) ? IF grade — validated for immunofluorescence with low background staining. Use to localize targets in cells/tissue by fluorescence microscopy. 1.0 mg/ml in H₂O
    En Stock Articulo #: O1501802
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    Sinónimos
    Hoechst 33342 Stain Solution (1 mg/mL) | Hoechst 33342 Staining Solution for Live Cells, 100X | Hoechst 33342 Solution
  7. Hoechst 33258 staining solution
    CAS: 23491-45-4 Número EC: 245-690-6 PubChem CID: 31953 Formula: C25H24N6O·3HCl Peso molecular: 533.90
    Liquid BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. Ready-to-use ? Ready-to-use — supplied pre-formulated at working concentration, no prep needed. Use to save time and reduce pipetting/dilution errors. Biological Stain ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. for Fluorescence analysis ? Fluorescence-analysis grade — very low fluorescent impurities for clean spectra. Use in fluorescence assays where background interferes. Biological dye grade ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. for Microscopy ? Microscopy grade — reagents/stains suited to sample prep and imaging. Use in microscopy where clarity and low background are needed. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. Suitable for Immunofluorescence(IF) ? IF grade — validated for immunofluorescence with low background staining. Use to localize targets in cells/tissue by fluorescence microscopy. 1.0 mg/mL in H₂O
    En Stock Articulo #: H1373484
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    Sinónimos
    Hoechst 33258 | Hoechst 33258 Stain Solution | Hoechst 33258 Stain Solution(1mg/ml) | Hoechst 33258 Staining Dye Solu...
  8. Sertaconazole nitrate, Cytochrome P450 51 inhibitor
    CAS: 99592-39-9 PubChem CID: 200103 Formula: C20H15Cl3N2OS·HNO3 Peso molecular: 500.78
    En Stock Articulo #: S129395
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    Nombre IUPAC
    1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
    SMILES
    C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-]
    InChIKey
    HAAITRDZHUANGT-UHFFFAOYSA-N
    InChI
    1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)
    Sinónimos
    HMS1571A12 | CAS-99592-39-9 | A851341 | 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H...
  9. GW 1929 hydrochloride
    CAS: 1217466-21-1 PubChem CID: 56972174 Formula: C30H29N3O4•HCl Peso molecular: 532.03
    Fuera de Stock Articulo #: G286659
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    Nombre IUPAC
    (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid;hydrochloride
    SMILES
    CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.Cl
    InChIKey
    KXNKIKXTGRMLEY-YCBFMBTMSA-N
    InChI
    1S/C30H29N3O4.ClH/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23;/h2-18,27,32H,19-show more
    Sinónimos
    N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride
  10. Lumbrokinase
    CAS: 556743-18-1
    EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. ≥12000U/mg
    En Stock Articulo #: L115121
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    Bioactividad
    ≥12000U/mg
  11. NCH 51
    CAS: 848354-66-5 Formula: C20H26N2O2S2 Peso molecular: 390.57
    En Stock Articulo #: N274711
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    Nombre IUPAC
    S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate
    SMILES
    CC(C)C(=O)SCCCCCCC(=O)NC1=NC(=CS1)C2=CC=CC=C2
    InChIKey
    MDYDGUOQFUQOGE-UHFFFAOYSA-N
    InChI
    1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)
    Sinónimos
    S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate | dibenzo[b,d]furan-4-yl boronic acid | N...
  12. Retaspimycin
    CAS: 857402-23-4 Formula: C31H45N3O8 Peso molecular: 587.7
    Fuera de Stock Articulo #: R127859
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    Nombre IUPAC
    [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13,20,22-trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(show more
    SMILES
    CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=C(C(=C2O)C1)NCC=C)O)C)OC)OC(=O)N)C)C)O)OC
    InChIKey
    OAKGNIRUXAZDQF-TXHRRWQRSA-N
    InChI
    1S/C31H45N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,show more
    Sinónimos
    D09375 | IPI-504 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13,20,22-Trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-...
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