6-(Methylamino)purine - ≥95% , CAS No.443-72-1

CAS: 443-72-1 Cat. No.: M184567 Peso molecular: 149.2 Número EC: 207-137-7

GRADE & PURITY ≥95%

Synonyms

FT-0653186 | NSC 11580 | n-methyl-Adenine | SCHEMBL21913 | AKOS028112370 | EINECS 207-137-7 | 6-Monomethylaminopurine | N6-Methyladenin | UNII-W7IBY2BGAX | 6-(Methylamino)purine | 6-MAP | MFCD00075820 | N-Methyl-9H-purin-6-amine | M3166 | NCGC00257570-01

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

6-(Methylamino)purine, 6-methylade is a reagent for substitution of adenine nucleotide analogs containing bicyclohexane ring system locked in northern conformation enhanced potency as py receptor antagonists. Adenine methylation as an epigenic mark has been observed in single-celled organisms and also rarely in mamalian cells.

Specifications

Sinónimos

FT-0653186 | NSC 11580 | n-methyl-Adenine | SCHEMBL21913 | AKOS028112370 | EINECS 207-137-7 | 6-Monomethylaminopurine | N6-Methyladenin | UNII-W7IBY2BGAX | 6-(Methylamino)purine | 6-MAP | MFCD00075820 | N-Methyl-9H-purin-6-amine | M3166 | NCGC00257570-01

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504754225
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504754225
• Sonrisas canónicas: CNC1=NC=NC2=C1NC=N2
• IUPAC Name: N-methyl-7H-purin-6-amine
• InChIKey: CKOMXBHMKXXTNW-UHFFFAOYSA-N
• INCHI: 1S/C6H7N5/c1-7-5-4-6(10-2-8-4)11-3-9-5/h2-3H,1H3,(H2,7,8,9,10,11)
• Isómeros SMILES: CNC1=NC=NC2=C1NC=N2
• Peso molecular: 149.2
• Reaxy-Rn: 7707
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7707&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Imidazopyrimidines
      • Subclass Purines and purine derivatives
        • Level5 6-aminopurines
          • Level6 6-alkylaminopurines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Imidazopyrimidines
• Subclass: Purines and purine derivatives
• Intermediate Tree Nodes: 6-aminopurines
• Direct Parent: 6-alkylaminopurines
• Alternative Parents: Secondary alkylarylamines Aminopyrimidines and derivatives Imidolactams Imidazoles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-alkylaminopurine - Aminopyrimidine - Secondary aliphatic/aromatic amine - Pyrimidine - Imidolactam - Azole - Imidazole - Heteroaromatic compound - Secondary amine - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
• External Descriptors: methyladenine - 6-alkylaminopurine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

YTHDF2 Tbio YTH domain-containing family protein 2 (23 Activities)

Discover Target: YTHDF2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO (Slightly, Heated), Methanol (Slightly, Heated)
• Punto de fusión (°C): 308 °C
• Peso molecular: 149.150 g/mol
• XLogP3: 0.600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 149.07 Da
• Monoisotopic Mass: 149.07 Da
• Topological Polar Surface Area: 66.500 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 139.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1