Ac-IEPD-CHO - ≥95% , CAS No.A276505

CAS: A276505 Cat. No.: A276505 Peso molecular: 498.53

GRADE & PURITY ≥95%

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Reversible inhibitor of Granzyme B and caspase B. The reversible inhibitor of Granzyme B can also inhibit caspase B. Granzyme B is a protease that participates in the induction of rapid target cell death through cytotoxic lymphocytes. 

Product description：

The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Specifications

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

Reversible granzyme B (K i = 80 nM) and caspase-8 inhibitor. Also inhibits caspase-7 (K i = 550 nM) and apoptosis in multiple biological systems. Main target Granzyme B The product does not compete with ATP. Reversibility: Yes Cell permeability: No

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Peso molecular: 498.53

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO