Acetylthiocholine iodide - ≥98% , CAS No.1866-15-5

CAS: 1866-15-5 Cat. No.: A100869 Peso molecular: 289.18 Beilstein Registry Number: 3916578 Número EC: 217-474-1 PubChem CID: 74629
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
SY022189 | NSC 44139 | PEG-5 Lauryl ether | 2-acetylsulfanylethyl(trimethyl)azanium;iodide | S-Acetylthiocholine iodide | ((2-Mercaptoethyl)trimethylammonium iodide acetate) | (2-Mercaptoethyl)trimethylammonium iodide, acetate | NTBLZMAMTZXLBP-UHFFFAOYSA-
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1g
A100869-1g
5

19,90US$

29,90US$
Guardar 10,00 US$ (33.44%)
5g
A100869-5g
10

34,90US$

52,90US$
Guardar 18,00 US$ (34.03%)
25g
A100869-25g
≥10

144,90US$

217,90US$
Guardar 73,00 US$ (33.50%)
100g
A100869-100g
2

463,90US$

695,90US$
Guardar 232,00 US$ (33.34%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 85 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Acetylthiocholine iodide is an AChE (acetylcholinesterase) substrate and AChR (nicotinic acetylcholine receptor)agonist.
A nAChR agonist and substrate of acetylcholinesterase

Specifications

Sinónimos
SY022189 | NSC 44139 | PEG-5 Lauryl ether | 2-acetylsulfanylethyl(trimethyl)azanium;iodide | S-Acetylthiocholine iodide | ((2-Mercaptoethyl)trimethylammonium iodide acetate) | (2-Mercaptoethyl)trimethylammonium iodide, acetate | NTBLZMAMTZXLBP-UHFFFAOYSA-
Especificaciones y pureza
≥98%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Nombres e identificadores
Pubchem Sid488184955
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488184955
Sonrisas canónicasCC(=O)SCC[N+](C)(C)C.[I-]
IUPAC Name2-acetylsulfanylethyl(trimethyl)azanium;iodide
InChIKeyNTBLZMAMTZXLBP-UHFFFAOYSA-M
INCHI1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
Isómeros SMILES CC(=O)SCC[N+](C)(C)C.[I-]
WGK Alemania 3
RTECS FZ9865000
PubChem CID 74629
Número ONU 2811
Peso molecular 289.18
Beilstein 3916578
Reaxy-Rn 3916578

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClaseOrganonitrogen compounds
SubclassQuaternary ammonium salts
Intermediate Tree Nodes Not available
Direct ParentTetraalkylammonium salts
Alternative Parents Thioesters  Carbothioic S-esters  Sulfenyl compounds  Carboxylic acids and derivatives  Organopnictogen compounds  Organic oxides  Organic iodide salts  Hydrocarbon derivatives  Carbonyl compounds  Amines  
Molecular FrameworkAliphatic acyclic compounds
Substituents Tetraalkylammonium salt - Thiocarboxylic acid ester - Carbothioic s-ester - Carboxylic acid derivative - Thiocarboxylic acid or derivatives - Sulfenyl compound - Amine - Organic iodide salt - Organic salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organosulfur compound - Organooxygen compound - Organic oxygen compound - Carbonyl group - Aliphatic acyclic compound
DescripciónThis compound belongs to the class of organic compounds known as tetraalkylammonium salts. These are organonitrogen compounds containing a quaternary ammonium substituted with four alkyl chains.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

28 results found

Lot NumberCertificate TypeFechaArticulo
G2220246Certificate of AnalysisJan 26, 2026 A100869
J2509143Certificate of AnalysisAug 22, 2025 A100869
J2509142Certificate of AnalysisAug 22, 2025 A100869
J2509141Certificate of AnalysisAug 22, 2025 A100869
B2527326Certificate of AnalysisMar 10, 2025 A100869
L2413492Certificate of AnalysisDec 02, 2024 A100869
L2413491Certificate of AnalysisDec 02, 2024 A100869
L2413490Certificate of AnalysisDec 02, 2024 A100869
L2413489Certificate of AnalysisDec 02, 2024 A100869
A2305035Certificate of AnalysisOct 22, 2024 A100869
A2305062Certificate of AnalysisOct 22, 2024 A100869
A2305061Certificate of AnalysisOct 22, 2024 A100869
A2305059Certificate of AnalysisOct 15, 2024 A100869
A2305026Certificate of AnalysisOct 15, 2024 A100869
A2305033Certificate of AnalysisOct 15, 2024 A100869
A2305052Certificate of AnalysisOct 15, 2024 A100869
G2417092Certificate of AnalysisApr 11, 2024 A100869
D2425216Certificate of AnalysisApr 11, 2024 A100869
G2220251Certificate of AnalysisApr 07, 2024 A100869
K1913041Certificate of AnalysisJun 05, 2023 A100869
G2115063Certificate of AnalysisApr 18, 2023 A100869
G2115062Certificate of AnalysisApr 18, 2023 A100869
G2115061Certificate of AnalysisApr 18, 2023 A100869
G2115060Certificate of AnalysisApr 18, 2023 A100869
L2023091Certificate of AnalysisOct 18, 2022 A100869
A2305034Certificate of AnalysisOct 14, 2022 A100869
G2220258Certificate of AnalysisJun 01, 2022 A100869
G2220253Certificate of AnalysisJun 01, 2022 A100869

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Propiedades químicas y físicas
SolubilidadSoluble in water,
SensibilidadMoisture,Light and Heat sensitive
Punto de fusión (°C)205-210°C
Peso molecular289.180 g/mol
XLogP3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass289 Da
Monoisotopic Mass289 Da
Topological Polar Surface Area42.400 Ų
Heavy Atom Count11
Formal Charge0
Complexity117.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Bing Zhang, Yu Wang, Donghui Wu, Qilin Zhao, Yaoyao Chen, Yushu Li, Jian Sun, Xiurong Yang.  (2023)  Fluorescent assay for acetylcholinesterase activity and inhibitor screening based on lanthanide organic/inorganic hybrid materials.  Analytical Methods,  16  (2): (314-321).  [PMID:38116865] [10.1039/D3AY01925J]
2. Shuanghong Dong, Jucheng Xia, Fang Wang, Lili Yang, Siqi Xing, Jiyu Du, Tingting Zhang, Zeng Li.  (2023)  Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:38052155] [10.1016/j.ejmech.2023.116013]
3. Xu Feifei, Li Xinyang, Chen Chen, Liang Zhigang, Xu Guanhong, Wei Fangdi, Yang Jing, Hu Qin, Cen Yao.  (2023)  A dual-emission ratiometric fluorescence strategy with enzyme-based inhibition for organophosphorus pesticides determination.  MICROCHIMICA ACTA,  190  (8): (1-8).  [PMID:37516685] [10.1007/s00604-023-05923-8]
4. Yalan Cui, Xuejun Chen, Jingjing Shi, Qian Jin, Ruihua Zhang, Tong Shi, Chen Wang, Liqin Li.  (2023)  Study of Huperzine A derivatives with extended protection against soman intoxication.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:37517785] [10.1016/j.taap.2023.116646]
5. Jianjin GUO, Lu BAI, Chi-Tang HO, Sen GUO, Naisheng BAI.  (2023)  Chemical characterization, multivariate analysis and in vitro bioactivity evaluation of the roots of Fraxinus mandshurica.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.cjac.2023.100303]
6. Xin Cui, Jiachen Zhang, Yitong Liu, Wen Shao, Yawen Tang, Hanjun Sun.  (2023)  A Portable Nanozyme-Strip Fabricated by Ru-ZIF-8 with Dual Nanozymatic Activity for Detection of Acetylcholine.  ChemNanoMat,  (10): (e202300310).  [PMID:] [10.1002/cnma.202300310]
7. Xie Wenfei, Liu Jinrui, Qu Yunting, Du Fangkai.  (2023)  Construction of a ratiometric fluorescent sensing platform based on near-infrared carbon dots for organophosphorus pesticides detection.  ANALYTICAL SCIENCES,  39  (7): (1097-1106).  [PMID:36944823] [10.1007/s44211-023-00319-3]
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9. Cui Xiang, Deng Shanshan, Li Guoyin, Zhang Yunxia, Wang Lining, Wu Changjing, Deng Yanru.  (2022)  Butenolide derivatives from Aspergillus terreus selectively inhibit butyrylcholinesterase.  Frontiers in Chemistry,      [PMID:36618870] [10.3389/fchem.2022.1063284]
10. Juan Lu, Xiangyu Shan, Qian Wu, Yingjie Zhao, Chao Li, Huiling Li, Shuning Yang, Li Tian.  (2022)  ZnO-Fe2O3 based electrochemiluminescence sensor for sensitive detection of malathion.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2022.108321]
11. Huiyan Wang, Mengyang Su, Xuli Shi, Xiangyu Li, Xinyu Zhang, Aihong Yang, Rui Shen.  (2022)  Design, Synthesis, Calculation and Biological Activity Studies Based on Privileged Coumarin Derivatives as Multifunctional Anti-AD Lead Compound.  CHEMISTRY & BIODIVERSITY,  20  (1): (e202200867).  [PMID:36461922] [10.1002/cbdv.202200867]
12. Yijing Liao, Xi Mai, Xiaqing Wu, Xing Hu, Xiaoqiao Luo, Guowen Zhang.  (2022)  Exploring the Inhibition of Quercetin on Acetylcholinesterase by Multispectroscopic and In Silico Approaches and Evaluation of Its Neuroprotective Effects on PC12 Cells.  MOLECULES,  27  (22): (7971).  [PMID:36432070] [10.3390/molecules27227971]
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14. Hongxia Li, Changshun Su, Ni Liu, Ting Lv, Chuanyu Yang, Qi Lu, Chunyan Sun, Xu Yan.  (2022)  Carbon Dot-Anchored Cobalt Oxyhydroxide Composite-Based Hydrogel Sensor for On-Site Monitoring of Organophosphorus Pesticides.  ACS Applied Materials & Interfaces,      [PMID:36380517] [10.1021/acsami.2c17450]
15. Wang Zhenxing, Jin Ximeng, Zhang Xuechun, Xie Xing, Tu Zongcai, He Xiahong.  (2022)  From Function to Metabolome: Metabolomic Analysis Reveals the Effect of Probiotic Fermentation on the Chemical Compositions and Biological Activities of Perilla frutescens Leaves.  Frontiers in Nutrition,      [PMID:35898707] [10.3389/fnut.2022.933193]
16. Jing Li, Guangyi Yang, Wenfeng Shi, Xiaoping Fang, Lintao Han, Yan Cao.  (2022)  Anti-Alzheimer's disease active components screened out and identified from Hedyotis diffusa combining bioaffinity ultrafiltration LC-MS with acetylcholinesterase.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:35714878] [10.1016/j.jep.2022.115460]
17. Xin Lu, Yijun Liu, Nan Qin, Chenxi Du, Yanyu Hu, Yao Chen, Haopeng Sun.  (2022)  Discovery of Tryptophan-tetrahydroisoquinoline Derivatives as Multifunctional Agents for Treatment of Alzheimer's Disease.  CHINESE JOURNAL OF CHEMISTRY,  40  (15): (1821-1830).  [PMID:] [10.1002/cjoc.202200096]
18. Wang Tuhui, Zhang Lening, Xin Hua.  (2022)  A Portable Fluorescent Hydrogel-Based Device for On-Site Quantitation of Organophosphorus Pesticides as Low as the Sub-ppb Level.  Frontiers in Chemistry,      [PMID:35572106] [10.3389/fchem.2022.855281]
19. Aihong Yang, Wenjing Liu, Xiangyu Li, Wanru Wu, Xiaodi Kou, Rui Shen.  (2022)  Study on the novel usnic acid derivatives: Design, synthesis, X-Ray crystal structure of Cu(II) complex and anti-AD activities.  JOURNAL OF MOLECULAR STRUCTURE,      [PMID:] [10.1016/j.molstruc.2022.133018]
20. Yaoyao Feng, Yujiao Qu, Xiaobo Sun, Wei Pan, Jinping Wang.  (2022)  Fluorimetric and ratiometric colorimetric dual-mode detection of organophosphorus pesticides based on carbon dots/DTNB.  NEW JOURNAL OF CHEMISTRY,  46  (17): (8022-8028).  [PMID:] [10.1039/D1NJ06011B]
21. Yijing Liao, Xing Hu, Junhui Pan, Guowen Zhang.  (2022)  Inhibitory Mechanism of Baicalein on Acetylcholinesterase: Inhibitory Interaction, Conformational Change, and Computational Simulation.  Foods,  11  (2): (168).  [PMID:35053900] [10.3390/foods11020168]
22. Cui-Cui Sun, Zhong-Ping Yin, Ji-Guang Chen, Wen-Jun Wang, Guo-Dong Zheng, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang.  (2021)  Dihydromyricetin Improves Cognitive Impairments in d-Galactose-Induced Aging Mice through Regulating Oxidative Stress and Inhibition of Acetylcholinesterase.  MOLECULAR NUTRITION & FOOD RESEARCH,  66  (4): (2101002).  [PMID:34932880] [10.1002/mnfr.202101002]
23. Xu Jing, Jing Wu, Huihui Wang, Luyao Guo, Xiaojiao Zheng, Xiaowen Wang, Shuo Wang.  (2021)  Application of deep eutectic solvent-based extraction coupled with an S-CQD fluorescent sensor for the determination of pirimicarb in cereals.  FOOD CHEMISTRY,      [PMID:34662796] [10.1016/j.foodchem.2021.131360]
24. Hui-Peng Song, Hui Zhang, Rui Hu, Hong-He Xiao, Hua Guo, Wei-Hong Yuan, Xin-Tong Han, Xin-Yi Xu, Xin Zhang, Zi-Xuan Ding, Ming-Yue Zhao, Ting-Guo Kang, Hui-Yang Sun, An Chang, Yue-Hua Chen, Ming Xie.  (2021)  A strategy to discover lead chemome from traditional Chinese medicines based on natural chromatogram-effect correlation (NCEC) and natural structure-effect correlation (NSEC): Mahonia bealei and Mahonia fortunei as a case study.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:34500403] [10.1016/j.jchromb.2021.122922]
25. Hua Guo, Yue-Hua Chen, Tian-Min Wang, Ting-Guo Kang, Hui-Yang Sun, Wen-Han Pei, Hui-Peng Song, Hui Zhang.  (2021)  A strategy to discover selective α-glucosidase/acetylcholinesterase inhibitors from five function-similar citrus herbs through LC-Q-TOF-MS, bioassay and virtual screening.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:33992880] [10.1016/j.jchromb.2021.122722]
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30. Shaochun Shi, Huibin Wang, Jian Wang, Yvxi Wang, Xiaobian Xue, Zilin Hou, Guo-Dong Yao, Xiao-Xiao Huang, Hongwei Zhao, Qingbo Liu, Shao-Jiang Song.  (2020)  Semi-synthesis and biological evaluation of flavone hybrids as multifunctional agents for the potential treatment of Alzheimer's disease.  BIOORGANIC CHEMISTRY,      [PMID:32442817] [10.1016/j.bioorg.2020.103917]
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34. Sen Guo, Li Liu, Shanshan Zhang, Chuang Yang, Wenping Yue, Haoan Zhao, Chi-Tang Ho, Junfeng Du, Hai Zhang, Naisheng Bai.  (2019)  Chemical characterization of the main bioactive polyphenols from the roots of Morus australis (mulberry).  Food & Function,  10  (10): (6915-6926).  [PMID:31588440] [10.1039/C9FO01457H]
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36. Yue Cai, Jingkun Fang, Bingfeng Wang, Fangshuai Zhang, Guang Shao, Yingju Liu.  (2019)  A signal-on detection of organophosphorus pesticides by fluorescent probe based on aggregation-induced emission.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2019.04.123]
37. Lunjie Huang, Da-Wen Sun, Hongbin Pu, Qingyi Wei, Linpin Luo, Jianlong Wang.  (2019)  A colorimetric paper sensor based on the domino reaction of acetylcholinesterase and degradable γ-MnOOH nanozyme for sensitive detection of organophosphorus pesticides.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2019.04.020]
38. Qi Fenglian, Yan Chunxiao, Meng Zihui, Li Shuguang, Xu Jiayu, Hu Xiaochun, Xue Min.  (2019)  Acetylcholinesterase-functionalized two-dimensional photonic crystal for the sensing of G-series nerve agents.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  411  (12): (2577-2585).  [PMID:30847569] [10.1007/s00216-019-01700-w]
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45. Qiao Liu, Yu-Jiao Peng, Jin-Chun Xu, Cheng Ma, Lingling Li, Chang-Jie Mao, Jun-Jie Zhu.  (2017)  Label-Free Electrochemiluminescence Aptasensor for Highly Sensitive Detection of Acetylcholinesterase Based on Au-Nanoparticle-Functionalized g-C3N4 Nanohybrid.  ChemElectroChem,  (7): (1768-1774).  [PMID:] [10.1002/celc.201700035]
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47. Pengjuan Ni, Yujing Sun, Shu Jiang, Wangdong Lu, Yilin Wang, Zhen Li, Zhuang Li.  (2016)  Label-free detection of acetylcholinesterase and its inhibitor based on the in situ formation of fluorescent copper nanoparticles.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2016.08.096]
48. Ni Pengjuan, Sun Yujing, Dai Haichao, Jiang Shu, Lu Wangdong, Wang Yilin, Li Zhen, Li Zhuang.  (2016)  Colorimetric determination of the activity of acetylcholinesterase and its inhibitors by exploiting the iodide-catalyzed oxidation of 3,3′,5,5′-tetramethylbenzidine by hydrogen peroxide.  MICROCHIMICA ACTA,  183  (9): (2589-2595).  [PMID:] [10.1007/s00604-016-1874-8]
49. Jiafu Chang, Haiyin Li, Ting Hou, Feng Li.  (2016)  Paper-based fluorescent sensor for rapid naked-eye detection of acetylcholinesterase activity and organophosphorus pesticides with high sensitivity and selectivity.  BIOSENSORS & BIOELECTRONICS,      [PMID:27498323] [10.1016/j.bios.2016.07.022]
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