Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 32 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Aciclovir is a synthetic nucleoside analogue active against herpesviruses.
An antiviral compound that can be used to induce apoptosis.
| Pubchem Sid | 488202820 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488202820 |
| Sonrisas canónicas | C1=NC2=C(N1COCCO)N=C(NC2=O)N |
| IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one |
| InChIKey | MKUXAQIIEYXACX-UHFFFAOYSA-N |
| INCHI | 1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15) |
| Isómeros SMILES | C1=NC2=C(N1COCCO)N=C(NC2=O)N |
| WGK Alemania | 2 |
| RTECS | UP0791400 |
| Peso molecular | 225.2 |
| Reaxy-Rn | 1219402 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1219402&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Imidazopyrimidines |
| Subclass | Purines and purine derivatives |
| Intermediate Tree Nodes | Purinones |
| Direct Parent | Hypoxanthines |
| Alternative Parents | 6-oxopurines Pyrimidones Aminopyrimidines and derivatives N-substituted imidazoles Vinylogous amides Heteroaromatic compounds Azacyclic compounds Primary amines Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | 6-oxopurine - Hypoxanthine - Aminopyrimidine - Pyrimidone - N-substituted imidazole - Pyrimidine - Azole - Imidazole - Heteroaromatic compound - Vinylogous amide - Azacycle - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Amine - Alcohol - Primary amine - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring. |
| External Descriptors | oxopurine - 2-aminopurines |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | May 09, 2026 | A126073 | |
| Certificate of Analysis | May 09, 2026 | A126073 | |
| Certificate of Analysis | May 09, 2026 | A126073 | |
| Certificate of Analysis | May 09, 2026 | A126073 | |
| Certificate of Analysis | Apr 07, 2026 | A126073 | |
| Certificate of Analysis | Mar 11, 2026 | A126073 | |
| Certificate of Analysis | Mar 11, 2026 | A126073 | |
| Certificate of Analysis | Dec 06, 2024 | A126073 | |
| Certificate of Analysis | Dec 06, 2024 | A126073 | |
| Certificate of Analysis | Dec 06, 2024 | A126073 | |
| Certificate of Analysis | Dec 06, 2024 | A126073 | |
| Certificate of Analysis | Jul 23, 2024 | A126073 | |
| Certificate of Analysis | Jul 23, 2024 | A126073 | |
| Certificate of Analysis | Jul 23, 2024 | A126073 | |
| Certificate of Analysis | Jul 23, 2024 | A126073 | |
| Certificate of Analysis | Jul 23, 2024 | A126073 | |
| Certificate of Analysis | Jun 27, 2024 | A126073 | |
| Certificate of Analysis | Jun 27, 2024 | A126073 | |
| Certificate of Analysis | May 31, 2024 | A126073 | |
| Certificate of Analysis | May 10, 2023 | A126073 | |
| Certificate of Analysis | Sep 20, 2022 | A126073 | |
| Certificate of Analysis | Jun 23, 2022 | A126073 | |
| Certificate of Analysis | Jun 23, 2022 | A126073 | |
| Certificate of Analysis | Jun 23, 2022 | A126073 | |
| Certificate of Analysis | Jun 23, 2022 | A126073 | |
| Certificate of Analysis | Jun 23, 2022 | A126073 |
| Solubilidad | Soluble in water (partly), DMSO (50 mg/ml), DMF (1 mg/ml), 1eq. HCl (50 mM), and dilute alkalies. |
|---|---|
| Punto de fusión (°C) | 262°C |
| Peso molecular | 225.200 g/mol |
| XLogP3 | -1.900 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 225.086 Da |
| Monoisotopic Mass | 225.086 Da |
| Topological Polar Surface Area | 115.000 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 308.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 2. Xinyu Song, Yang Shi, Zelin Wu, Bingkun Huang, Xinhao Wang, Heng Zhang, Peng Zhou, Wen Liu, Zhicheng Pan, Zhaokun Xiong, Bo Lai. (2023) Unraveling the discriminative mechanisms for peroxy activation via atomically dispersed Fe-N5 sites for tunable water decontamination. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2023.123240] |
| 3. Ting Zhang, Ge Bai, Nan Cai, Yongqian Lei, Pengran Guo, Jingwei Xu. (2023) The carbon-doped Fe3O4 montmorillonite particle electrode for the degradation of antiviral drugs in electro-Fenton system. APPLIED CLAY SCIENCE, [PMID:] [10.1016/j.clay.2023.107056] |
| 4. Fan-Zhi Bu, Yue-Ming Yu, Min Zhang, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li. (2023) Directed Self-Assembly with Gallic Acid Provides First Phenolic Acid Cocrystals for the Antiviral Drug Acyclovir toward Increasing Pharmaceutical Features and Synergy: A Theoretical and Experimental Integration Research. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.3c00489] |
| 5. Shuang Shan, Jie Hu, Zhiyun Zheng, Shuangying Gui, Yanqiu Long, Danqing Wu, Ning He. (2023) Development and Assessment of Acyclovir Gel Plaster Containing Sponge Spicules. JOURNAL OF PHARMACEUTICAL SCIENCES, [PMID:37331627] [10.1016/j.xphs.2023.06.008] |
| 6. Liu Yang, Hao Wu, Congcong Luo, Yang Zhao, Rongbo Dai, Zhiqing Li, Xu Zhang, Ze Gong, Zeyu Cai, Yicong Shen, Fang Yu, Wei Li, Hongmei Zhao, Tao Zhang, Junming Zhu, Yi Fu, Jing Wang, Wei Kong. (2023) Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, [PMID:37128913] [10.1161/ATVBAHA.122.318788] |
| 7. Yahan Yu, Chunxiu Yu, Zelin Wu, Bingkun Huang, Peng Zhou, Heng Zhang, Wen Liu, Yucheng Liu, Zhaokun Xiong, Bo Lai. (2023) Switching the primary mechanism from a radical to a nonradical pathway in electrocatalytic ozonation by onsite alternating anode and cathode. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.141340] |
| 8. Yanping Wei, Liangyuan Yao, Yiyong Wu, Xia Liu, Jinxia Feng, Jianhua Ding, Kanghua Li, Quanguo He. (2022) Ultrasensitive electrochemical detection for nanomolarity Acyclovir at ferrous molybdate nanorods and graphene oxide composited glassy carbon electrode. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.128601] |
| 9. Zhihua Song, Yanqin Song, Yinghao Wang, Jinqiu Liu, Yumeng Wang, Wen Lin, Yaqi Wang, Jinhua Li, Jiping Ma, Gangqiang Yang, Lingxin Chen. (2021) Chromatographic performance of zidovudine imprinted polymers coated silica stationary phases. TALANTA, [PMID:34890940] [10.1016/j.talanta.2021.123115] |
| 10. Muning Chen, Jian Lu, Jia Gao, Chao Yu, Wendong Xing, Jiangdong Dai, Minjia Meng, Yongsheng Yan, Yilin Wu. (2021) Design of self-cleaning molecularly imprinted membrane with antibacterial ability for high-selectively separation of ribavirin. JOURNAL OF MEMBRANE SCIENCE, [PMID:] [10.1016/j.memsci.2021.119994] |
| 11. Xiaoyu Xu, Zishan Zeng, Xin Ding, Ting Shan, Qiuxing Liu, Meixu Chen, Jie Chen, Meng Xia, Yuanfeng He, Zeqian Huang, Yanjuan Huang, Chunshun Zhao. (2021) Reactive oxygen species-activatable self-amplifying Watson-Crick base pairing-inspired supramolecular nanoprodrug for tumor-specific therapy. BIOMATERIALS, [PMID:34537502] [10.1016/j.biomaterials.2021.121128] |
| 12. Qi Tian, Peng Quan, Liang Fang, Hui Xu, Chao Liu. (2021) A molecular mechanism investigation of the transdermal/topical absorption classification system on the basis of drug skin permeation and skin retention. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:34506925] [10.1016/j.ijpharm.2021.121082] |
| 13. Binge Deng, Xia Luo, Meng Zhang, Liming Ye, Yu Chen. (2018) Quantitative detection of acyclovir by surface enhanced Raman spectroscopy using a portable Raman spectrometer coupled with multivariate data analysis. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:30308453] [10.1016/j.colsurfb.2018.09.058] |
| 14. Chunyang Nie, Zhimin Ao, Xiaoguang Duan, Chengying Wang, Shaobin Wang, Taicheng An. (2018) Degradation of aniline by electrochemical activation of peroxydisulfate at MWCNT cathode: The proofed concept of nonradical oxidation process. CHEMOSPHERE, [PMID:29758500] [10.1016/j.chemosphere.2018.04.173] |
| 15. Yu-Feng Shen, Lei Liu, Wei-Chao Chen, Yang Hu, Bin Zhu, Gao-Xue Wang. (2017) Evaluation on the antiviral activity of arctigenin against spring viraemia of carp virus. AQUACULTURE, [PMID:32287458] [10.1016/j.aquaculture.2017.09.001] |
| 16. Ting Wu, Haixin Li, Jiasheng Chen, Ying Cao, Weimin Fu, Pingzheng Zhou, Jianxin Pang. (2017) Apigenin, a novel candidate involving herb-drug interaction (HDI), interacts with organic anion transporter 1 (OAT1). Pharmacological Reports, [PMID:29128807] [10.1016/j.pharep.2017.06.012] |
| 17. Tianwei Lv, Hongyuan Yan, Jiankun Cao, Shiru Liang. (2015) Hydrophilic Molecularly Imprinted Resorcinol–Formaldehyde–Melamine Resin Prepared in Water with Excellent Molecular Recognition in Aqueous Matrices. ANALYTICAL CHEMISTRY, [PMID:26441379] [10.1021/acs.analchem.5b03253] |
| 18. Kaida Kuang, Ya Li, Yang Chen, Yu Ji, Nengqin Jia. (2024) A simplified molecularly imprinted ECL sensor based on Mn2SnO4 nanocubes for sensitive detection of ribavirin. ANALYST, 149 (4): (1318-1326). [PMID:38251970] [10.1039/D3AN02077K] |
| 19. Yijun Jia, Zhao Zhao, Leyang Chen, Yongqi Liu, Bin Zhu. (2025) Carbon Nanotube-Based Drug Delivery System Increases Drug Content and Promotes Immune Response in Mandarin Fish. Fishes, 10 (3): (92). [PMID:] [10.3390/fishes10030092] |
| 20. Hang Cui, Jing Yan, Faguang Ma, Zequan Diao, Ming Yan, Yilin Wu, Jianming Pan. (2024) Construction of nano-cage imprinted sites in MOFs-based membrane for precise identification and separation. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.130051] |
| 21. Mingya Yao, Shuofeng Zhang, Meng Xie, Lingxi Zhao, Ru-Song Zhao. (2024) Efficient activation of peracetic acid by cobalt modified nitrogen-doped carbon nanotubes for drugs degradation: Performance and mechanism insight. CHEMOSPHERE, [PMID:38719118] [10.1016/j.chemosphere.2024.142277] |
| 22. Lanlan Wei, Lin Wang, Lu Chen, Yifan Ru, Lianzhong Shen, Yu Ye, Zhouwei Li, Qizhou Dai. (2024) Electrocatalytic Degradation of Acyclovir by Three-Dimensional Porous Lead Dioxide Anodes: Condition Optimization, Kinetic Analysis and Degradation Mechanisms. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 171 (1): (013503). [PMID:] [10.1149/1945-7111/ad1372] |
| 23. Xiaoyan Chen, Jiangdong Cui, Xinyu Yang, Taoyue Yuan, Jiacheng Ge, Mengtao Ma, Shunke Ding, Wenhai Chu. (2024) Enhanced removal of phenolic contaminants with permanganate oxidation mediated by SiO2@TEMPO: Performance, transformation pathway, and selectivity. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.158210] |
| 24. Hongda Zhang, Guanghui Xu, Yong Yu. (2024) Photocatalytic activation of peracetic acid by metal–free C2N3 for efficient water purification under visible light: High–efficiency bifurcated electron transport. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.150035] |
| 25. Jing Yan, Yingrui Sui, Faguang Ma, Jian Lu, Yilin Wu. (2024) Precise selection and separation of ribavirin by nanoconfined imprinted MOFs membrane. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.126784] |
| 26. Songjie Fan, Xiaotian Chang, Yan Qiao, Xiaoxiao Zhao, Jiafu Zhao, Heshui Zhu, Yingqian Han, Chao Zhang. (2025) Tandemly Repeated G-Quadruplex Structures in the Pseudorabies Virus Genome: Implications for Epiberberine-Based Antiviral Therapy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26 (8): (3764). [PMID:40332400] [10.3390/ijms26083764] |
| 27. Yilin Wu, Yanke Xu, Faguang Ma, Jingjing Zhen, Yue Li, Fanlei Kong, Ming Yan. (2025) Optimization of hollow ZIF-8/GO composite imprinted membrane synthesis by polyphenol etching technique and study of its selective separation performance for ribavirin. DESALINATION, [PMID:] [10.1016/j.desal.2025.119066] |
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