AEBSF Solution - 10mg/ml in H2O , CAS No.30827-99-7

CAS: 30827-99-7 Cat. No.: A301913 Peso molecular: 239.69 Beilstein Registry Number: 7604627 Número EC: 608-547-2 PubChem CID: 186136
Disponible para pedir
GRADE & PURITY 10mg/ml in H2O
Synonyms
Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride | DHA6VL95HL | 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride [for biochemical research] | EX-A2487 | T70748 | AKOS015847774 | Pefabloc(R) SC, certified reference material, TraceCERT(R) |
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
0.5ml
A301913-0.5ml
2

100,90US$

117,90US$
Guardar 17,00 US$ (14.42%)
2×0.5ml
A301913-2×0.5ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

155,90US$

212,90US$
Guardar 57,00 US$ (26.77%)
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Why this grade

10mg/ml in H2O for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride | DHA6VL95HL | 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride [for biochemical research] | EX-A2487 | T70748 | AKOS015847774 | Pefabloc(R) SC, certified reference material, TraceCERT(R) |
Especificaciones y pureza
10mg/ml in H2O
Mecanismos bioquímicos y fisiológicos
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, impr
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores
Sonrisas canónicasC1=CC(=CC=C1CCN)S(=O)(=O)F.Cl
IUPAC Name4-(2-aminoethyl)benzenesulfonyl fluoride;hydrochloride
InChIKeyWRDABNWSWOHGMS-UHFFFAOYSA-N
INCHI1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
Isómeros SMILES C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl
WGK Alemania 3
PubChem CID 186136
Número ONU 3261
Peso molecular 239.69
Beilstein 7604627
Reaxy-Rn 7604627

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassPhenethylamines
Intermediate Tree Nodes Not available
Direct ParentPhenethylamines
Alternative Parents Benzenesulfonyl compounds  2-arylethylamines  Aralkylamines  Sulfonyls  Sulfonyl fluorides  Organosulfonic acids and derivatives  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Phenethylamine - Benzenesulfonyl group - 2-arylethylamine - Aralkylamine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl fluoride - Sulfonyl halide - Sulfonyl - Organic nitrogen compound - Hydrochloride - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Amine - Organosulfur compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as phenethylamines. These are compounds containing a phenethylamine moiety, which consists of a phenyl group substituted at the second position by an ethan-1-amine.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLG Tclin Plasminogen (2339 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CTSG Tchem Cathepsin G (2304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CELA2A Pancreatic elastase (395 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeFechaArticulo
C2604250Certificate of AnalysisFeb 02, 2026 A301913
F2110978Certificate of AnalysisMay 12, 2023 A301913
Propiedades químicas y físicas
SolubilidadSoluble in water 50 mg/mL or 100% ethanol.
SensibilidadMoisture Sensitive
Punto de fusión (°C)181-185°C
Peso molecular239.700 g/mol
XLogP3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass239.018 Da
Monoisotopic Mass239.018 Da
Topological Polar Surface Area68.500 Ų
Heavy Atom Count14
Formal Charge0
Complexity239.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Preguntas frecuentes y artículos
Protease Inhibitors
Buffer Additives to Prevent Protein Precipitation
Common Protectants and Formulations for Protein Storage
How to Optimize Buffer Components for Ni-Agarose Beads
Three Main Differences Between AEBSF and PMSF Protease Inhibitors
Proteinase K: Frequently Asked Questions
Review of Chymotrypsin: Enzymological Properties, Catalytic Mechanism, and Research Applications
Review of Collagenase: Enzymological Features, Type Systems, and Research Applications
Clostridial Proteases: Classification, Molecular Mechanisms, and Research Applications
Furin: A Review of Its Structural Features, Substrate Recognition, and Research Applications
SuFEx and Sulfonyl Fluorides: From S(VI)–F Click Ligation Reactions to Covalent Tools in Chemical Biology
Citations of This Product
Referencias
1. Chenglin Li, Sifan Li, Xinsheng Li, Tao Yuan, Jialei Xu, Xixin Gu, Jianli Hua.  (2023)  A Turn-On Lipid Droplet-Targeted Near-Infrared Fluorescent Probe with a Large Stokes Shift for Detection of Intracellular Carboxylesterases and Cell Viability Imaging.  MOLECULES,  28  (5): (2317).  [PMID:36903562] [10.3390/molecules28052317]
2. Yi-Xuan Fu, Wu-Yingzheng Guo, Nan Wang, Yi-Jie Dai, Zi-Ye Zhang, Xin-Lin Sun, Wen-Chao Yang, Guang-Fu Yang.  (2022)  Diagnosis of Bacterial Plant Diseases via a Nitroreductase-Activated Fluorescent Sensor.  ANALYTICAL CHEMISTRY,      [PMID:36469707] [10.1021/acs.analchem.2c04614]
3. Jingmin Zhang, Youmei Peng, Ying Li, Ning Wang, Yuna Chai, Chongzhen Qin, Xinru Wang, Suna Liu, Yubing Zhou, Xiaojian Zhang, Wenda Zhang.  (2021)  Development of a near-infrared fluorescent probe with large Stokes shift for carboxylesterases detection and its application in living systems.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2021.109993]
4. Yu Zhu Yang, Zi Yi Xu, Nian Bing Li, Hong Qun Luo.  (2021)  Ultrasensitive fluorescent probe for visual biosensing of esterase activity in living cells and its imaging application.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:34175764] [10.1016/j.saa.2021.120094]
5. Shuli Man, Miao Li, Jin Zhou, Haiyue Wang, Jinyan Zhang, Long Ma.  (2019)  Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-κB and TGF-β signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation.  Biomaterials Science,  (1): (201-211).  [PMID:31664285] [10.1039/C9BM01563A]
6. Hui Zhou, Jinbao Tang, Jie Zhang, Bochao Chen, Jianfei Kan, Weifen Zhang, Jin Zhou, Huimin Ma.  (2019)  A red lysosome-targeted fluorescent probe for carboxylesterase detection and bioimaging.  Journal of Materials Chemistry B,  (18): (2989-2996).  [PMID:] [10.1039/C9TB00310J]
7. Juan Wang, Mengmeng Song, Chengguo Hu, Kangbing Wu.  (2018)  Portable, Self-Powered, and Light-Addressable Photoelectrochemical Sensing Platforms Using pH Meter Readouts for High-Throughput Screening of Thrombin Inhibitor Drugs.  ANALYTICAL CHEMISTRY,      [PMID:29998727] [10.1021/acs.analchem.8b01979]
8. Wu Can, Zhang Xiao Wei, Wang Manman, Sun Jinpan, Chen Jianfei, Guan Yanbin, Pang Xin.  (2025)  Trypsin-instructed bioactive peptide nanodrugs with cascading transformations to improve chemotherapy against colon cancer.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-20).  [PMID:39891144] [10.1186/s12951-025-03143-1]
9. Yue Wang, Fang Yuan, Chenshu Wu, Lulu Ning, Yihan Zhao, Ji-Wei Shen, Tony D. James, Jianjian Zhang, Yuan Guo.  (2026)  Hydrogen Sulfide Donor Featuring Dual-Modal Imaging for the Theranostic Management of Drug-Induced Liver Injury.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:] [10.1021/acs.jmedchem.5c03427]
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