Atraric acid - Moligand™, 10 mM in DMSO , CAS No.4707-47-5

CAS: 4707-47-5 Cat. No.: A1499934 Peso molecular: 196.2 Número EC: 225-193-0
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Argon charged,Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Estado
Price
Qty
1ml
A1499934-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
35,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases .

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Argon charged, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Nombres e identificadores
Isómeros SMILES CC1=CC(=C(C(=C1C(=O)OC)O)C)O
WGK Alemania 2
Peso molecular 196.2
Reaxy-Rn 2099269
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2099269&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Mengxin Li, Wanqi Wu, Zhihao Ma, Shasha Zhang, Tianyue Guan, Jun Wang, Long Chen, Wanyi Xu, Hong Yu, Huizhen Chen, Jingquan Dong.  (2025)  Atraric acid alleviates chronic intermittent hypoxia-induced renal fibrosis by inhibiting oxidative stress and ferroptosis in obstructive sleep apnea mice through the Nrf2/GPX4 pathway.  CELLULAR SIGNALLING,      [PMID:40754121] [10.1016/j.cellsig.2025.112040]
2. Jingjing Chen, Lu Zhou, Mengxin Li, Jun Wang, Yaru Chen, Jing Xia, Yue Lin, Huizhen Chen, Zibo Dong.  (2025)  Atraric acid attenuates chronic intermittent hypoxia-induced lung injury by inhibiting ferroptosis through activation of the NRF2 pathway.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:40897231] [10.1016/j.taap.2025.117540]
3. Mengxin Li, Jun Wang, Zihan Xu, Yue Lin, Jingquan Dong.  (2025)  Atraric Acid Attenuates Chronic Intermittent Hypoxia-Induced Brain Injury via AMPK-Mediated Nrf2 and FoxO3a Antioxidant Pathway Activation.  PHYTOMEDICINE,      [PMID:40975041] [10.1016/j.phymed.2025.157261]
Calculadoras de soluciones
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📚 Citations by Application

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