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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11 nM.
Appearance:Solid
IC50& Target:IC50: 11 nM (FLT3)
In Vitro:BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11nM. Phosphorylation of all FLT3-WT, FLT3-IDT, and FLT3-D835Y are inhibited by BPR1J-097 Hydrochloride at a concentration as low as 10 nM. BPR1J-097 Hydrochloride suppresses th
In Vivo:After i.v. administration of mice with BPR1J-097 Hydrochloride at two cycles of 10 or 25mg/kg, a clear dose-dependent anti-tumour effect is observed. Tumours in mice treated with BPR1J-097 Hydrochloride (25mg/kg per day) stop growing. BPR1J-097 Hydrochl
Biological Activity:BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC 50 of 11u2009nM.
| Peso molecular | 553.08 |
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Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Solubilidad | DMSO : 6 mg/mL (10.85 mM; Need ultrasonic and warming) H2O : 2 mg/mL (3.62 mM; Need ultrasonic) |
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| Sensibilidad | Moisture sensitive |