Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| ALogP | 5.1 |
|---|
| Pubchem Sid | 488195207 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195207 |
| Sonrisas canónicas | CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C |
| IUPAC Name | (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol |
| InChIKey | GMRQFYUYWCNGIN-NKMMMXOESA-N |
| INCHI | 1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1 |
| Isómeros SMILES | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C |
| WGK Alemania | 3 |
| RTECS | FZ4645000 |
| Peso molecular | 416.64 |
| Beilstein | 7559394 |
| Reaxy-Rn | 30827300 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30827300&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Clase | Steroids and steroid derivatives |
| Subclass | Vitamin D and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Vitamin D and derivatives |
| Alternative Parents | Triterpenoids Tertiary alcohols Secondary alcohols Cyclic alcohols and derivatives Hydrocarbon derivatives |
| Molecular Framework | Aliphatic homopolycyclic compounds |
| Substituents | Triterpenoid - Tertiary alcohol - Cyclic alcohol - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homopolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as vitamin d and derivatives. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. |
| External Descriptors | Vitamin D3 and derivatives |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Dec 16, 2024 | C120126 | |
| Certificate of Analysis | Dec 16, 2024 | C120126 | |
| Certificate of Analysis | Nov 04, 2024 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | May 10, 2023 | C120126 | |
| Certificate of Analysis | Jul 19, 2022 | C120126 | |
| Certificate of Analysis | Jun 21, 2022 | C120126 | |
| Certificate of Analysis | Jun 21, 2022 | C120126 | |
| Certificate of Analysis | Jun 21, 2022 | C120126 |
| Sensibilidad | Air Sensitive,Heat Sensitive |
|---|---|
| Punto de fusión (°C) | 119°C(lit.) |
| Peso molecular | 416.600 g/mol |
| XLogP3 | 5.100 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 6 |
| Exact Mass | 416.329 Da |
| Monoisotopic Mass | 416.329 Da |
| Topological Polar Surface Area | 60.700 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 688.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 6 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 2 |
| Covalently-Bonded Unit Count | 1 |
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| 2. Pingcui Xu, Bingfeng Lin, Xuehui Deng, Kai Huang, Yan Zhang, Nani Wang. (2022) VDR activation attenuates osteoblastic ferroptosis and senescence by stimulating the Nrf2/GPX4 pathway in age-related osteoporosis. FREE RADICAL BIOLOGY AND MEDICINE, [PMID:36402439] [10.1016/j.freeradbiomed.2022.11.013] |
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| 4. Chen Xue-qi, Mao Jia-yu, Wang Chun-saier, Li Wen-bin, Han Tao-tao, Lv Ke, Li Jing-nan. (2022) CYP24A1 Involvement in Inflammatory Factor Regulation Occurs via the Wnt Signaling Pathway. Current Medical Science, 42 (5): (1022-1032). [PMID:36255661] [10.1007/s11596-022-2564-x] |
| 5. Xiaonan Chen, Yiqing Zou, Shuqi Zhang, Pengchao Fang, Shuxuan Li, Pengyu Li, Yingying Sun, Gang Yuan, Haiyan Hu. (2022) Multi-functional vesicles improve Helicobacter pylori eradication by a comprehensive strategy based on complex pathological microenvironment. Acta Pharmaceutica Sinica B, [PMID:36176916] [10.1016/j.apsb.2022.05.014] |
| 6. Yongzhi Cui, Yuanyuan Guo, Li Kong, Jingyu Shi, Ping Liu, Rui Li, Yongtao Geng, Weihang Gao, Zhiping Zhang, Dehao Fu. (2021) A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis. Bioactive Materials, [PMID:34901540] [10.1016/j.bioactmat.2021.09.015] |
| 7. Huiling Chen, Kaiqiang Hu, Yaru Liang, Yuqi Gao, Chenye Zeng, Kang Xu, Xiaojin Shi, Liyuan Li, Yuemiao Yin, Yi Qiao, Ying Qiu, Qingfei Liu, Zhao Wang. (2021) Ample dietary fat reduced the risk of primary vesical calculi by inducing macrophages to engulf budding crystals in mice. Acta Pharmaceutica Sinica B, [PMID:35256944] [10.1016/j.apsb.2021.08.001] |
| 8. Zehua Li, Ji Wu, Xiuli Zhang, Caiwen Ou, Xinglong Zhong, Yanting Chen, Lihe Lu, Hailin Liu, Yining Li, Xiaoyu Liu, Bo Wu, Yuxi Wang, Pingzhen Yang, Jianyun Yan, Minsheng Chen. (2019) CDC42 promotes vascular calcification in chronic kidney disease. JOURNAL OF PATHOLOGY, 249 (4): (461-471). [PMID:31397884] [10.1002/path.5334] |
| 9. Hailin Liu, Xiuli Zhang, Xinglong Zhong, Zehua Li, Shaoai Cai, Pingzhen Yang, Caiwen Ou, Minsheng Chen. (2019) Puerarin inhibits vascular calcification of uremic rats. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:31085237] [10.1016/j.ejphar.2019.05.023] |
| 10. Meihui Fan, Guowen Zhang, Junhui Pan, Deming Gong. (2017) An inhibition mechanism of dihydromyricetin on tyrosinase and the joint effects of vitamins B6, D3 or E. Food & Function, 8 (7): (2601-2610). [PMID:28686246] [10.1039/C7FO00236J] |
| 11. Wang Sikai, Cheng Hongxia, Li Miaomiao, Gao Dongmei, Wu Haoran, Zhang Shanshan, Huang Yilan, Guo Kun. (2024) BNIP3-mediated mitophagy boosts the competitive growth of Lenvatinib-resistant cells via energy metabolism reprogramming in HCC. Cell Death & Disease, 15 (7): (1-18). [PMID:38969639] [10.1038/s41419-024-06870-9] |
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| 14. Fang Liu, Qingchun Liang, Li Li, Yuan Gong, Mingxi Li, Liyun Feng, An Chen, Yuanzhi Ye, Zirong Lan, Yining Li, Jing-Song Ou, Lihe Lu, Jianyun Yan. (2025) Thrombospondin-1 binds to integrin β3 to inhibit vascular calcification through suppression of NF-κB pathway. JOURNAL OF PATHOLOGY, [PMID:40084742] [10.1002/path.6417] |
| 15. Xuemin Xian, Xin Zhao, Xingchen Zhou, Hanfang Liu, Changxi Li, Xinquan Wu, Yuhang Chen, Keyue Ye, Hongwei Yang, Mingxi Li, Jianyun Yan, Xiuli Zhang. (2025) Honokiol attenuates oxidative stress and vascular calcification via the upregulation of heme oxygenase-1 in chronic kidney disease. TOXICOLOGY AND APPLIED PHARMACOLOGY, [PMID:40194744] [10.1016/j.taap.2025.117318] |
| 16. Zhenyu Zhu, Hao Liu, Liyun Feng, Lihe Lu, Jiahui Zhu, Qingchun Liang, Zirong Lan, Yuanzhi Ye, Siyi Wang, An Chen, Jianyun Yan. (2025) Loss of ADAMTS5 promotes vascular calcification via versican/integrin β1/FAK signal. ATHEROSCLEROSIS, [PMID:40215897] [10.1016/j.atherosclerosis.2025.119190] |
| 17. Zhu Mengyao, Ren Lu, Xiao Wenlong, Wang Longjian, Hu Zhiming, Wang Nani. (2025) Senkyunolide I suppresses hepatic stellate cell activation and liver fibrosis by reprogramming VDR-dependent fatty acid metabolism. Chinese Medicine, 20 (1): (1-17). [PMID:40514735] [10.1186/s13020-025-01133-x] |
| 18. Shangheng Fan, Youbo Yu, Yunqin Wei, Jing An, Qi Wang, Yan Yang. (2025) Targeting the mTOR-mitochondrial function axis: Calcitriol attenuates sarcopenic obesity with lipid dysregulation etiology. FREE RADICAL BIOLOGY AND MEDICINE, [PMID:41173312] [10.1016/j.freeradbiomed.2025.10.282] |
| 19. Ding Liu, Yuanzhi Ye, Zirong Lan, An Chen, Xingchen Zhou, Zhenhao Li, Xin Wen, Jisheng Xiao, Fan Ouyang, Jianyun Yan. (2025) Ultrasmall Cu2−xSe nanoparticles alleviate vascular calcification through inhibiting oxidative stress and NF-κB/NLRP3-mediated inflammation. Redox Biology, [PMID:41353801] [10.1016/j.redox.2025.103961] |
| 20. Ruman Chen, Jiqing He, Na An, Mingzhi Xu, Liheng Wang, Yafei Bai. (2026) MiR-181c-5p-SIRT1 axis-driven Pink1/Parkin-mediated mitophagy prevents ferroptosis and vascular calcification in chronic kidney disease. EXPERIMENTAL CELL RESEARCH, [PMID:41512994] [10.1016/j.yexcr.2025.114875] |
| 21. Chengsi Li, Jing Li, Chengyingjie Yang, Zhenghao Zhu, Yachen Zhang, Yin Xiang. (2026) Vericiguat improves CKD-related vascular calcification through the NO/cGMP/PKG pathway. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:41723893] [10.1016/j.intimp.2026.116413] |
| 22. Guangxiao Zhang, Yawen Sun, Ling He, Bowen Zhao, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Min Liu, Kelin Li, Hai Lin, Haifang Li. (2026) In ovo injection of vitamin D3 improves intestinal development of chicks via activating vitamin D receptor. POULTRY SCIENCE, 105 (5): (106672). [PMID:41723960] [10.1016/j.psj.2026.106672] |
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →