CDK12-IN-3 - ≥99% , CAS No.2220184-50-7
Disponible
SKU
C647924
CDK12-IN-3 is a potent and selective CDK12 inhibitor with an IC 50 of 491 nM in enzymatic assay.
In Vitro
CDK12-IN-3 is a highly selective CDK12 inhibitor. CDK12-IN-3 (0.1 μM) shows potent inhibition of phosphorylation of Ser2 on the CTD repeat domain of RNA Pol II as well as growth inhibition of OV90 cells and acute cytotoxicity to THP1 cells.. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:CDK12 491 nM (IC 50 )
Más Información
| CAS | 2220184-50-7 |
|---|---|
| Especificaciones y pureza | ≥99% |
| Condiciones de almacenamiento de almacenamiento | Store at -20°C |
| Enviado en | Ice chest + Ice pads |
| Product Description | CDK12-IN-3 is a potent and selective CDK12 inhibitor with an IC 50 of 491 nM in enzymatic assay. In Vitro CDK12-IN-3 is a highly selective CDK12 inhibitor. CDK12-IN-3 (0.1 μM) shows potent inhibition of phosphorylation of Ser2 on the CTD repeat domain of RNA Pol II as well as growth inhibition of OV90 cells and acute cytotoxicity to THP1 cells.. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CDK12 491 nM (IC 50 ) |
| Solubilidad | DMSO : 250 mg/mL (531.33 mM; Need ultrasonic) |
| PubChem CID | 134691746 |
| Fórmula molecular | C23H28F2N8O |
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