≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Product description：
CHR-6494 TFA is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR-6494 TFA inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer.
| Pubchem Sid | 488202516 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488202516 |
| Sonrisas canónicas | CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1.C(=O)(C(F)(F)F)O |
| IUPAC Name | 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine;2,2,2-trifluoroacetic acid |
| InChIKey | ILWYDZNXJQESDI-UHFFFAOYSA-N |
| INCHI | 1S/C16H16N6.C2HF3O2/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13;3-2(4,5)1(6)7/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20);(H,6,7) |
| Isómeros SMILES | CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1.C(=O)(C(F)(F)F)O |
| Peso molecular | 406.36 |
| Reaxy-Rn | 38829337 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38829337&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Benzopyrazoles |
| Subclass | Indazoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indazoles |
| Alternative Parents | Aminopyridazines Benzenoids Imidolactams N-substituted imidazoles Alpha-halocarboxylic acids Pyrazoles Heteroaromatic compounds Carboxylic acids Azacyclic compounds Monocarboxylic acids and derivatives Amines Carbonyl compounds Organofluorides Alkyl fluorides Hydrocarbon derivatives Organic oxides |
| Molecular Framework | Not available |
| Substituents | Benzopyrazole - Indazole - Aminopyridazine - N-substituted imidazole - Pyridazine - Benzenoid - Imidolactam - Alpha-halocarboxylic acid - Heteroaromatic compound - Pyrazole - Alpha-halocarboxylic acid or derivatives - Azole - Imidazole - Azacycle - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organic oxide - Alkyl fluoride - Organohalogen compound - Carbonyl group - Organic oxygen compound - Organofluoride - Organic nitrogen compound - Amine - Organonitrogen compound - Organooxygen compound - Alkyl halide - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as indazoles. These are compounds containing an indazole, which is structurally characterized by a pyrazole fused to a benzene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 C2624109 | Certificate of Analysis | Apr 07, 2026 | C288680 |
| E2315096 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315097 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315101 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E23151022 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315103 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315107 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315110 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315111 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E23151126 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315965 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315973 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| E2315988 | Certificate of Analysis | Feb 05, 2026 | C288680 |
| Solubilidad | Solvent:DMSO, Max Conc. mg/mL: 40.64, Max Conc. mM: 100 |
|---|---|
| Peso molecular | 406.400 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 4 |
| Exact Mass | 406.137 Da |
| Monoisotopic Mass | 406.137 Da |
| Topological Polar Surface Area | 108.000 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 461.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
