GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%
Potent, competitive AMPA/kainate glutamate receptor antagonist.Potent, competitive AMPA / kainate receptor antagonist. Also antagonist at NMDA receptor glycine site.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
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Grado
Moligand™
Tipo de acción
ANTAGONIST
Mecanismo de acción
Antagonist of GluA1;Antagonist of GluA2;GluA3;GluA4
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as quinoxalines. These are compounds containing a quinoxaline moiety, a bicyclic heterocycle made up of a benzene ring fused to a pyrazine ring.
External Descriptors
quinoxaline derivative
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Huijun Li, Xin Xu, Jiwei Wang, Xuefeng Han, Zhouqing Xu. (2021) A Robust PVDF-Assisted Composite Membrane for Tetracycline Degradation in Emulsion and Oil-Water Separation. Nanomaterials, 11 (12):(3201). [PMID:34947550][10.3390/nano11123201]
2.Shuling Shen, Junjie Wang, Zhujun Wu, Zheng Du, Zhihong Tang, Junhe Yang. (2020) Graphene Quantum Dots with High Yield and High Quality Synthesized from Low Cost Precursor of Aphanitic Graphite. Nanomaterials, 10 (2):(375). [PMID:32098041][10.3390/nano10020375]
3.Zhicheng Wang, Shuping Nie, Ru Xia, Yang Lv, Ming Cao, Ming Chen, Qiannian Dong, Lifen Su, Peng Chen, Bin Yang, Jibin Miao, Zhengzhi Zheng, Jiasheng Qian. (2018) Preparation of the Yellow-Colored Aluminum Pigments with Double-Layer Structure Using a Crosslinked Copolymeric Dye. Polymers, 10 (10):(1097). [PMID:30961022][10.3390/polym10101097]
4.Juan Li, Zhen Li, Yanbo Liu, Yijing Li, Yanqiong Wu, Anne Manyande, Zhixiao Li, Hongbing Xiang. (2024) Lysophosphatidylcholine induced by fat transplantation regulates hyperalgesia by affecting the dysfunction of ACC perineuronal nets. iScience, [PMID:39640595][10.1016/j.isci.2024.111274]
5.Huanhuan Gao, Hui Liu, Peihui Xu, Jianzhong Liu. (2024) Micro-explosion-induced combustion and agglomeration characteristics in composite propellants with fluorinated graphene. ACTA ASTRONAUTICA, [PMID:][10.1016/j.actaastro.2024.09.050]
6.Wei Du, Xiaomin Zhang, Songze Li, Xin Xie. (2024) Novel Perspective on Sevoflurane-Induced Cognitive Dysfunction: Implications of Neuronal SIRPα and Microglial Synaptic Remodeling. ACS Chemical Neuroscience, [PMID:39644326][10.1021/acschemneuro.4c00485]
Calculadoras de soluciones
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Reseñas
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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