Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Name: Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
SKU: C104537
Availability: InStock

CAS: 50-22-6 Cat. No.: C104537 Fórmula: C₂₁H₃₀O₄ Peso molecular: 346.46 Beilstein Registry Number: 2339601 Número EC: 200-019-6

59 Citations COA

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Corticosterone - Moligand™, ≥98% CAS No(50-22-6) by Aladdin Scientific

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Disponible para pedir

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Preguntas frecuentes y artículos Citations of This Product Calculadoras de soluciones Reseñas

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 59 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Corticosterone, the major stress hormone, is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
Corticosteroid is an activator of MCR.

Specifications

Sinónimos

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

Endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors.

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Pureza

≥98%

Nombres e identificadores

Pubchem Sid

528773721

Sonrisas canónicas

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O

IUPAC Name

(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

InChIKey

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

INCHI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

Isómeros SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O

WGK Alemania

RTECS

GM7650000

Peso molecular

346.46

Beilstein

2339601

Reaxy-Rn

2063664

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2063664&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Clase Steroids and steroid derivatives
    - Subclass Hydroxysteroids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Clase	Steroids and steroid derivatives
Subclass	Hydroxysteroids
Intermediate Tree Nodes	Not available
Direct Parent	21-hydroxysteroids
Alternative Parents	Gluco/mineralocorticoids, progestogins and derivatives 20-oxosteroids 3-oxo delta-4-steroids 11-beta-hydroxysteroids Delta-4-steroids Cyclohexenones Alpha-hydroxy ketones Secondary alcohols Cyclic alcohols and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic homopolycyclic compounds
Substituents	Progestogin-skeleton - 21-hydroxysteroid - Pregnane-skeleton - 20-oxosteroid - 3-oxo-delta-4-steroid - 3-oxosteroid - 11-hydroxysteroid - 11-beta-hydroxysteroid - Oxosteroid - Delta-4-steroid - Cyclohexenone - Alpha-hydroxy ketone - Cyclic alcohol - Ketone - Secondary alcohol - Cyclic ketone - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Alcohol - Organooxygen compound - Primary alcohol - Aliphatic homopolycyclic compound
Descripción	This compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
External Descriptors	C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

NR3C1 Tclin Glucocorticoid receptor (1 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC22A3 Tchem Solute carrier family 22 member 3 (1 Activities)

Discover Target: SLC22A3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SHBG Tchem Sex hormone-binding globulin (1 Activities)

Discover Target: SHBG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C2 Tclin Mineralocorticoid receptor (1 Activities)

Discover Target: NR3C2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SERPINA6 Tchem Corticosteroid-binding globulin (2 Activities)

Discover Target: SERPINA6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR3C2 Tclin Mineralocorticoid receptor (2134 Activities)

Discover Target: NR3C2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SERPINA6 Tchem Corticosteroid binding globulin (274 Activities)

Discover Target: SERPINA6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EBP Tchem 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (102 Activities)

Discover Target: EBP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

Discover Target: NR1H4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MTOR Tclin Serine/threonine-protein kinase mTOR (13850 Activities)

Discover Target: MTOR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)

Discover Target: NFKB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)

Discover Target: UGT1A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Lot Number	Certificate Type	Fecha	Articulo
A2630362	Certificate of Analysis	Jan 15, 2026	C104537
A2630363	Certificate of Analysis	Jan 15, 2026	C104537
A2630374	Certificate of Analysis	Jan 15, 2026	C104537
A2630376	Certificate of Analysis	Jan 15, 2026	C104537
A2521127	Certificate of Analysis	Jan 11, 2025	C104537
A2521130	Certificate of Analysis	Jan 11, 2025	C104537
A2521131	Certificate of Analysis	Jan 11, 2025	C104537
A2521138	Certificate of Analysis	Jan 11, 2025	C104537
F2516057	Certificate of Analysis	Jan 11, 2025	C104537
L2418788	Certificate of Analysis	Nov 30, 2024	C104537
A2510169	Certificate of Analysis	Nov 30, 2024	C104537
L2418787	Certificate of Analysis	Nov 30, 2024	C104537
L2418784	Certificate of Analysis	Nov 30, 2024	C104537
L2418775	Certificate of Analysis	Nov 30, 2024	C104537
J2408328	Certificate of Analysis	Sep 19, 2024	C104537
J2408327	Certificate of Analysis	Sep 19, 2024	C104537
J2408326	Certificate of Analysis	Sep 19, 2024	C104537
G2425158	Certificate of Analysis	Jul 05, 2024	C104537
G2425159	Certificate of Analysis	Jul 05, 2024	C104537
G2425160	Certificate of Analysis	Jul 05, 2024	C104537
G2425161	Certificate of Analysis	Jul 05, 2024	C104537
D2424132	Certificate of Analysis	Apr 10, 2024	C104537
D2424133	Certificate of Analysis	Apr 10, 2024	C104537
H2324224	Certificate of Analysis	Aug 03, 2023	C104537
H2324183	Certificate of Analysis	Aug 03, 2023	C104537
H2324219	Certificate of Analysis	Aug 03, 2023	C104537
H2324222	Certificate of Analysis	Aug 03, 2023	C104537
H2307598	Certificate of Analysis	Jul 11, 2023	C104537
B2302921	Certificate of Analysis	Dec 30, 2022	C104537
B2302817	Certificate of Analysis	Dec 30, 2022	C104537
B2302957	Certificate of Analysis	Dec 30, 2022	C104537
B2302878	Certificate of Analysis	Dec 30, 2022	C104537
I2202249	Certificate of Analysis	Jul 20, 2022	C104537
I2202250	Certificate of Analysis	Jul 20, 2022	C104537
I2202251	Certificate of Analysis	Jul 20, 2022	C104537
I2202252	Certificate of Analysis	Jul 20, 2022	C104537
G2208130	Certificate of Analysis	Jan 08, 2022	C104537
B2207303	Certificate of Analysis	Jan 08, 2022	C104537
B2207302	Certificate of Analysis	Jan 08, 2022	C104537
B2207301	Certificate of Analysis	Jan 08, 2022	C104537
B2207300	Certificate of Analysis	Jan 08, 2022	C104537

Solubilidad	Solvent:DMSO, Max Conc. mg/mL: 34.65, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.46, Max Conc. mM: 10
Sensibilidad	Hygroscopic
Rotación específica [α]	+221 to +226 deg(C=1, EtOH)
Punto de fusión (°C)	180-183°C
Peso molecular	346.500 g/mol
XLogP3	1.900
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	346.214 Da
Monoisotopic Mass	346.214 Da
Topological Polar Surface Area	74.600 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	638.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Storage & shipping

Quality documents

Literature proof

Descripción general

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reseñas de cliente

📚 Citations by Application

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