Neurosteroids are not merely steroid molecules delivered into brain tissue from the peripheral endocrine system, but rather a class of active steroids that can be synthesized locally within the central nervous system, further converted, and act on neurons, astrocytes, oligodendrocytes, and ...
The kinin system is a major molecular network linking tissue injury, inflammatory responses, vascular reactivity, and regulation of neural excitability. Through coordinated control of kinin generation, receptor stratification, ion-channel sensitization, and amplification of neuroinflammation, ...
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