Maleimida Cy5 - ≥95% , CAS No.1437796-65-0

CAS: 1437796-65-0 Cat. No.: C171350 Peso molecular: 641.24

GRADE & PURITY ≥95%

Synonyms

1437796-65-0 | 2-(5-(1-(6-((2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-6-oxohexyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1,3,3-trimethyl-3H-indol-1-ium chloride | 6-[(2Z)-3,3-Dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)pe

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Descripción general

La maleimida Cianina5 es un colorante monorreactivo que se acopla selectivamente con grupos tiol (por ejemplo, con cisteínas en péptidos y proteínas) para dar conjugados marcados. Cyanine5 es un análogo de Cy5®, un fluoróforo común que es compatible con diversos instrumentos como microscopios, generadores de imágenes y lectores de fluorescencia. Para el marcaje de anticuerpos y proteínas sensibles recomendamos utilizar la maleimida sulfo-Cianina5 soluble en agua.

Specifications

Sinónimos

1437796-65-0 | 2-(5-(1-(6-((2-(2, 5-Dioxo-2, 5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-6-oxohexyl)-3, 3-dimethylindolin-2-ylidene)penta-1, 3-dien-1-yl)-1, 3, 3-trimethyl-3H-indol-1-ium chloride | 6-[(2Z)-3, 3-Dimethyl-2-[(2E, 4E)-5-(1, 3, 3-trimethylindol-1-ium-2-yl)pe

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504773653
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773653
• Sonrisas canónicas: CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)NCCN5C(=O)C=CC5=O)(C)C)C)C.[Cl-]
• IUPAC Name: 6-[(2Z)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]hexanamide;chloride
• InChIKey: IATQCUIJHBSCGA-UHFFFAOYSA-N
• INCHI: 1S/C38H44N4O3.ClH/c1-37(2)28-16-11-13-18-30(28)40(5)32(37)20-8-6-9-21-33-38(3,4)29-17-12-14-19-31(29)41(33)26-15-7-10-22-34(43)39-25-27-42-35(44)23-24-36(42)45;/h6,8-9,11-14,16-21,23-24H,7,10,15,22,25-27H2,1-5H3;1H
• Isómeros SMILES: CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/C=C\3/C(C4=CC=CC=C4N3CCCCCC(=O)NCCN5C(=O)C=CC5=O)(C)C)C)C.[Cl-]
• Peso molecular: 641.24
• Reaxy-Rn: 27584855
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27584855&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Indoles and derivatives
      • Subclass Indoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Indoles and derivatives
• Subclass: Indoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 3-alkylindoles
• Alternative Parents: Tertiary alkylarylamines Maleimides Benzenoids N-acyl amines N-substituted carboxylic acid imides Dicarboximides Pyrrolines Amino acids and derivatives Secondary carboxylic acid amides Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Enamines Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic chloride salts Organic cations
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3-alkylindole - Tertiary aliphatic/aromatic amine - Maleimide - Fatty amide - N-acyl-amine - Fatty acyl - Carboxylic acid imide, n-substituted - Benzenoid - Carboxylic acid imide - Dicarboximide - Pyrroline - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Tertiary amine - Carboxylic acid derivative - Enamine - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic salt - Organic chloride salt - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Amine - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organic oxygen compound - Organic cation - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (31 uM, 23 mg/L)
• Sensibilidad: light sensitive

Referencias

1. Hang Yu, Rui Feng, Fenglin Chen, Zuodong Wu, Dehai Li, Xue Qiu.  (2024)  Rapid FRET Assay for the Early Detection of Alpha-Synuclein Aggregation in Parkinson’s Disease.  ACS Chemical Neuroscience,      [PMID:38506367] [10.1021/acschemneuro.3c00617]

2. Like Wang, Peiyan Feng, Bo Liu, Xiaonan Huang, Shouwei Yin.  (2025)  A Universal Co-Encapsulation Strategy for Hydrophilic and Hydrophobic Bioactives via Marangoni Effect-Driven Phase-Change Microcapsules.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2025.111522]