Cytochalasin B - Moligand™, 10 mM in DMSO , CAS No.14930-96-2

CAS: 14930-96-2 Cat. No.: C1498643 Peso molecular: 479.61 Beilstein Registry Number: 1096207 Número EC: 239-000-2
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
C1498643-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
377,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers , with K d value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Nombres e identificadores
Isómeros SMILES C[C@@H]1CCC[C@H](/C=C/C(=O)O[C@]23[C@@H](/C=C/C1)[C@@H](C(=C)[C@H]([C@H]2[C@@H](NC3=O)CC4=CC=CC=C4)C)O)O
WGK Alemania 3
RTECS RO0205000
Número ONU 1544
Peso molecular 479.61
Beilstein 1096207
Reaxy-Rn 949535
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=949535&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de fusión (°C)218-223°C
Citations of This Product
Referencias
1. Zixuan Dong, Song Liu, Xiaobing Liu, Dong He, Qi Chu, Linjie Zhong, Xiangyu Yu, Xiaoling Fu.  (2025)  Therapeutic Mitochondrial Transfer via Mesenchymal Stem Cell-Derived Microvesicles for Macrophage Modulation in Myocardial Infarction Complicated by Diabetes.  BIOMATERIALS,      [PMID:40706127] [10.1016/j.biomaterials.2025.123563]
2. Yaqi Feng, Mi Li.  (2023)  Micropipette-assisted atomic force microscopy for single-cell 3D manipulations and nanomechanical measurements.  Nanoscale,      [PMID:37526589] [10.1039/D3NR02404K]
3. Yuying Bai, Dawei Tian, Zhengxin Ren, Dangyang Yue, Qian Ren, Li Pei, Jun Pan.  (2023)  The dependences of mesenchymal stem cells commitments on the size, concentration, internalization and exposure time of Iron Oxide Nanoparticles through F-actin, Lamin A and ROS.  JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,      [PMID:36939155] [10.1002/jbm.a.37534]
4. Xinyue Li, Yuanyuan Fan, Zhengbao Zha, Deyan Gong, Jiajia Yu, Qianhui Li, Ruoyao Li, Hua Wang, Fei Wang.  (2023)  Cordycepin-Loaded Macrophage Vesicles for Targeted Nonalcoholic Steatohepatitis Attenuation.  ADVANCED FUNCTIONAL MATERIALS,  33  (18): (2214059).  [PMID:] [10.1002/adfm.202214059]
5. Sun Xiaoxi, Huang Bing, Pan Yuping, Fang Jinhua, Wang Hefeng, Ji Yanru, Ling Yingchen, Guo Pei, Lin Jiangguo, Li Quhuan, Fang Ying, Wu Jianhua.  (2022)  Spatiotemporal characteristics of P-selectin-induced β2 integrin activation of human neutrophils under flow.  Frontiers in Immunology,      [PMID:36439190] [10.3389/fimmu.2022.1023865]
6. Luchun Zhang, Meng Yuan, Xingwei Huang, Qianzi Cao, Shaogang Huang, Ruizhen Sun, Lei Lei.  (2022)  Inhibition of METTL5 improves preimplantation development of mouse somatic cell nuclear transfer embryos.  REPRODUCTION,      [PMID:36111643] [10.1530/REP-22-0169]
7. Zhe Chen, Qing Luo, Chuanchuan Lin, Dongdong Kuang, Guanbin Song.  (2016)  Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem cells via depolymerizing F-actin to impede TAZ nuclear translocation..  Scientific Reports,      [PMID:27444891] [10.1038/srep30322]
8. Gu Haiping, Lou Jun, Wang Haizhen, Yang Yu, Wu Laosheng, Wu Jianjun, Xu Jianming.  (2016)  Biodegradation, Biosorption of Phenanthrene and Its Trans-Membrane Transport by Massilia sp. WF1 and Phanerochaete chrysosporium.  Frontiers in Microbiology,      [PMID:26858710] [10.3389/fmicb.2016.00038]
9. Y.N. Lin, R. Jia, Y.H. Liu, Y. Gao, L.L. Wang, J.P. Kou, B.Y. Yu.  (2015)  Ruscogenin suppresses mouse neutrophil activation: Involvement of protein kinase A pathway.  JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY,      [PMID:26134424] [10.1016/j.jsbmb.2015.06.003]
10. Jiaqi Lin, Ziwei Lin, Anqi Huang, Xinyi Wu, Wei Yan, Daojun Liu, Chiju Wei, Wencan Xu.  (2025)  Effects of a PDGF-Stem Cell-Hydrogel Compound on Skin Wound Healing in Mice.  CYTOTHERAPY,      [PMID:40121568] [10.1016/j.jcyt.2025.01.001]
11. Di Wu, Hang Sun, Bingwei Yang, Erqun Song, Yang Song, Weihong Tan.  (2024)  Exosome Heterogeneity Affects the Distal “Barrier-Crossing” Trafficking of Exosome Encapsulated Quantum Dots.  ACS Nano,      [PMID:38394382] [10.1021/acsnano.3c09378]
12. Yijie Li, Shuni Duan, Yinhao Zhang, Runping Liu, Rong Sun, Jianzhi Wu, Zhi Ma, Xiaojiaoyang Li.  (2025)  Precise subcellular organelle-targeted analyses of hepatotoxicity of Polygonum multiflorum.  Chinese Herbal Medicines,      [PMID:41584695] [10.1016/j.chmed.2025.03.001]
13. Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu.  (2025)  Inhibition and Rescue of Hyperglycemia-Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell-Derived Microvesicles for Chronic Wound Healing.  Advanced Science,      [PMID:40407245] [10.1002/advs.202501612]
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