D-Fructose 6-phosphate disodium salt hydrate - ≥95% , CAS No.26177-86-6

CAS: 26177-86-6 Cat. No.: F113774 Peso molecular: 304.1（anhydrous） PubChem CID: 22812950

GRADE & PURITY ≥95%

Synonyms

D-Fructose, 6-(dihydrogen phosphate), sodium salt (1:2) | SCHEMBL3465198 | D-FRUCTOSE-6-PHOSPHATE DISODIUM SALT | D-Fructose-6-phosphate (disodium) salt | fructose 6-phosphate disodium salt | Sodium(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexylphosphate | dis

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

D-Fructose 6-phosphate (F6P) is a sμgar intermediate of the glycolytic pathway that may be used to help identify, differentiate and characterize enzymes such as phosphofructokinase(s), pyrophosphate-dependent fructose-6-phosphate 1-phosphotransferase(s), D-fructose-6-phosphate aldolase(s), glutamine:fructose-6-phosphate amidotransferase(s) and glucosamine-6P synthase(s).
A glycolytic intermediate formed by the isomerization of glucose-6-phosphate.

Specifications

Sinónimos

D-Fructose, 6-(dihydrogen phosphate), sodium salt (1:2) | SCHEMBL3465198 | D-FRUCTOSE-6-PHOSPHATE DISODIUM SALT | D-Fructose-6-phosphate (disodium) salt | fructose 6-phosphate disodium salt | Sodium(2R, 3R, 4S)-2, 3, 4, 6-tetrahydroxy-5-oxohexylphosphate | dis

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

Fructose-6-phosphate is a glycolytic intermediate produced by the isomerization of glucose-6-phosphate by phosphoglucoisomerase.Sugar intermediate of the glycolytic pathway produced by the isomerization of glucose-6-phosphate by phosphoglucoisomerase.

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 488200229
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488200229
• Sonrisas canónicas: C(C(C(C(C(=O)CO)O)O)O)OP(=O)([O-])[O-].[Na+].[Na+]
• IUPAC Name: disodium;[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl] phosphate
• InChIKey: WJTRLMLMSLDAPQ-CCXTYWFUSA-L
• INCHI: 1S/C6H13O9P.2Na/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;;/h4-7,9-11H,1-2H2,(H2,12,13,14);;/q;2*+1/p-2/t4-,5-,6-;;/m1../s1
• Isómeros SMILES: C([C@H]([C@H]([C@@H](C(=O)CO)O)O)O)OP(=O)([O-])[O-].[Na+].[Na+]
• PubChem CID: 22812950
• Peso molecular: 304.1（anhydrous）

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Monosaccharides
          • Level6 Hexoses
            • Level7 Hexose phosphates

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Monosaccharides - Hexoses
• Direct Parent: Hexose phosphates
• Alternative Parents: Monosaccharide phosphates Beta-hydroxy ketones Alkyl phosphates Acyloins Alpha-hydroxy ketones Secondary alcohols 1,2-diols Primary alcohols Organic sodium salts Organic oxides Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Hexose phosphate - Monosaccharide phosphate - Acyloin - Beta-hydroxy ketone - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Alpha-hydroxy ketone - Secondary alcohol - Ketone - 1,2-diol - Polyol - Organic alkali metal salt - Primary alcohol - Alcohol - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic salt - Organic sodium salt - Organic cation - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: H2O: 250 mg/mL (822.10 mM), Need ultrasonic
• Sensibilidad: light & moisture sensitive
• Peso molecular: 304.100 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 6
• Exact Mass: 303.994 Da
• Monoisotopic Mass: 303.994 Da
• Topological Polar Surface Area: 170.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 262.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Referencias

1. Ai Yuan-li, Wang Wei-jia, Liu Fan-jian, Fang Wei, Chen Hang-zi, Wu Liu-zheng, Hong Xuehui, Zhu Yuekun, Zhang Ci-xiong, Liu Long-yu, Hong Wen-bin, Zhou Bo, Chen Qi-tao, Wu Qiao.  (2023)  Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.  CELL RESEARCH,      [PMID:37460805] [10.1038/s41422-023-00848-6]