DL-α-Tocopherol - ≥96% , CAS No.10191-41-0

CAS: 10191-41-0 Cat. No.: T105540 Peso molecular: 430.71 Beilstein Registry Number: 94012 Número EC: 233-466-0
Disponible para pedir
GRADE & PURITY ≥96%
Synonyms
(+/-)-alpha-Tocopherol | (2R,8'R)-.alpha.-Tocopherol | 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol | DTXSID8021355 | Spectrum5_000381 | NSC82623 | (.+/-.)-.alpha.-Tocopherol | (2S, 4'S, 8'R)-alpha-Tocopherol | Antisterility vi
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5g
T105540-5g
4
9,90US$
25g
T105540-25g
3
18,90US$
100g
T105540-100g
2
59,90US$
500g
T105540-500g
2
209,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 57 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

DL-α-Tocopherol is a physiological membrane-bound antioxidant that protects cell membrane lipids from oxidative damage by free radicals.
An antioxidant that protects cell membrane lipids from oxidative damage

Specifications

Sinónimos
(+/-)-alpha-Tocopherol | (2R, 8'R)-.alpha.-Tocopherol | 2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-3, 4-dihydrochromen-6-ol | DTXSID8021355 | Spectrum5_000381 | NSC82623 | (.+/-.)-.alpha.-Tocopherol | (2S, 4'S, 8'R)-alpha-Tocopherol | Antisterility vi
Especificaciones y pureza
≥96%
Mecanismos bioquímicos y fisiológicos
Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥96%
Nombres e identificadores
Pubchem Sid488179662
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179662
Sonrisas canónicasCC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C
IUPAC Name2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol
InChIKeyGVJHHUAWPYXKBD-UHFFFAOYSA-N
INCHI1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
Isómeros SMILES CC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C
WGK Alemania 1
RTECS GA8746000
Peso molecular 430.71
Beilstein 94012
Reaxy-Rn 1296133
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1296133&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClasePrenol lipids
SubclassQuinone and hydroquinone lipids
Intermediate Tree Nodes Vitamin E compounds
Direct ParentTocopherols
Alternative Parents Diterpenoids  1-benzopyrans  Alkyl aryl ethers  Benzenoids  Oxacyclic compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Tocopherol - Diterpenoid - 1-benzopyran - Benzopyran - Chromane - Alkyl aryl ether - Benzenoid - Oxacycle - Organoheterocyclic compound - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as tocopherols. These are vitamin E derivatives containing a saturated trimethyltridecyl chain attached to the carbon C6 atom of a benzopyran ring system. The differ from tocotrienols that contain an unsaturated trimethyltrideca-3,7,11-trien-1-yl chain.
External Descriptors vitamin E
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
PSEN1 Tchem Presenilin 1 (302 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Brain (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

30 results found

Lot NumberCertificate TypeFechaArticulo
E2626622Certificate of AnalysisMay 14, 2026 T105540
E2626623Certificate of AnalysisMay 14, 2026 T105540
E2626624Certificate of AnalysisMay 14, 2026 T105540
E2626625Certificate of AnalysisMay 14, 2026 T105540
E2626626Certificate of AnalysisMay 14, 2026 T105540
H2304166Certificate of AnalysisMay 07, 2025 T105540
C2518692Certificate of AnalysisMar 06, 2025 T105540
C2518708Certificate of AnalysisMar 06, 2025 T105540
C2518701Certificate of AnalysisMar 06, 2025 T105540
C2518700Certificate of AnalysisMar 06, 2025 T105540
B2515071Certificate of AnalysisFeb 19, 2025 T105540
B2507038Certificate of AnalysisFeb 13, 2025 T105540
B23111076Certificate of AnalysisNov 08, 2024 T105540
B23111075Certificate of AnalysisNov 08, 2024 T105540
B23111104Certificate of AnalysisNov 04, 2024 T105540
J2429116Certificate of AnalysisNov 04, 2024 T105540
B23111088Certificate of AnalysisNov 04, 2024 T105540
B23111057Certificate of AnalysisNov 04, 2024 T105540
L2115670Certificate of AnalysisSep 19, 2023 T105540
L2115669Certificate of AnalysisSep 19, 2023 T105540
L2115667Certificate of AnalysisSep 19, 2023 T105540
D2112026Certificate of AnalysisJan 13, 2023 T105540
D2112023Certificate of AnalysisJan 13, 2023 T105540
E2429040Certificate of AnalysisOct 31, 2022 T105540
E2421063Certificate of AnalysisOct 31, 2022 T105540
B23111099Certificate of AnalysisOct 31, 2022 T105540
B23111062Certificate of AnalysisOct 31, 2022 T105540
B23111046Certificate of AnalysisOct 31, 2022 T105540
H2230037Certificate of AnalysisSep 05, 2022 T105540
E2322625Certificate of AnalysisNov 18, 2021 T105540

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Propiedades químicas y físicas
SolubilidadSoluble in vegetable oils, alcohol, ether, acetone, fats, and chloroform. Insoluble in water.
SensibilidadLight sensitive.
Índice de refracción1.505
Punto de inflamación (°F)235.4 °F
Punto de inflamación (°C)230°F
Punto de ebullición (°C)200-220°C
Punto de fusión (°C)2.5-3.5°C
Peso molecular430.700 g/mol
XLogP310.700
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count12
Exact Mass430.381 Da
Monoisotopic Mass430.381 Da
Topological Polar Surface Area29.500 Ų
Heavy Atom Count31
Formal Charge0
Complexity503.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Caiyun Cheng, Chao Yuan, Bo Cui, Jianpeng Li, Guimei Liu.  (2023)  β-Cyclodextrin based Pickering emulsions for α-tocopherol delivery: Antioxidation stability and bioaccessibility.  FOOD CHEMISTRY,      [PMID:38000154] [10.1016/j.foodchem.2023.138000]
2. Qian Zou, Weifei Wang, Qingqing Xu, Menglei Yan, Dongming Lan, Yonghua Wang.  (2023)  Influence of Proteins on Bioaccessibility of α-Tocopherol Encapsulation within High Diacylglycerol-Based Emulsions.  Foods,  12  (13): (2483).  [PMID:37444221] [10.3390/foods12132483]
3. Nouman Ali Shah, Rui Hong, Xue Yang, Shi-Shu Huang, Rizwan M. Gul, Yuwei Liu, Lingli Li, Jia-Zhuang Xu, Ka Li, Zhong-Ming Li.  (2023)  Synergy stabilization of vitamin E and D-sorbitol on crosslinked ultrahigh molecular weight polyethylene for artificial joint under in-vitro clinically relevant accelerated aging.  POLYMER DEGRADATION AND STABILITY,      [PMID:] [10.1016/j.polymdegradstab.2023.110382]
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10. Zihan Xu, Shanshan Liu, Mingyue Shen, Jianhua Xie, Jun Yang.  (2021)  Evaluation of trans fatty acids, carbonyl compounds and bioactive minor components in commercial linseed oils.  FOOD CHEMISTRY,      [PMID:34469834] [10.1016/j.foodchem.2021.130930]
11. Ri-Tong Lan, Yue Ren, Xin Wei, Li-Zhi Tang, Nouman Ali Shah, Lu Xu, Shi-Shu Huang, Rizwan M. Gul, Jia-Zhuang Xu, Zhong-Ming Li.  (2021)  Synergy between vitamin E and D-sorbitol in enhancing oxidation stability of highly crosslinked ultrahigh molecular weight polyethylene.  Acta Biomaterialia,      [PMID:34311104] [10.1016/j.actbio.2021.07.041]
12. Wenjiang Dong, Qiyu Chen, Changqing Wei, Rongsuo Hu, Yuzhou Long, Ying Zong, Zhong Chu.  (2021)  Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity.  ULTRASONICS SONOCHEMISTRY,      [PMID:33965776] [10.1016/j.ultsonch.2021.105578]
13. Liu Shanshan, Hu Huiyu, Yu Yanpeng, Zhao Jiahui, Liu Lichun, Zhao Shanshan, Xie Jianhua, Li Chang, Shen Mingyue.  (2021)  Simultaneous Determination of Tocopherols, Phytosterols, and Squalene in Vegetable Oils by High Performance Liquid Chromatography-Tandem Mass Spectrometry.  Food Analytical Methods,  14  (8): (1567-1576).  [PMID:] [10.1007/s12161-021-01987-5]
14. Fei-Fei Qi, Tian-You Ma, Ya-Meng Fan, Lan-ling Chu, Yan Liu, Yan Yu.  (2020)  Nanoparticle-based polyacrylonitrile monolithic column for highly efficient micro solid-phase extraction of carotenoids and vitamins in human serum.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:33278673] [10.1016/j.chroma.2020.461755]
15. Liangliang Zhang, Chenyu Liu, Fugui Li, Weihong Qiao.  (2020)  Performance Improvement of Cleaning Formulations for the Exterior Surface of High-Speed Trains.  JOURNAL OF SURFACTANTS AND DETERGENTS,  24  (1): (99-109).  [PMID:] [10.1002/jsde.12464]
16. Hang Yin, Bohong Du, Yue Chen, Nijia Song, Zhen Li, Jiehua Li, Feng Luo, Hong Tan.  (2020)  Dual-encapsulated biodegradable 3D scaffold from liposome and waterborne polyurethane for local drug control release in breast cancer therapy.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:32663417] [10.1080/09205063.2020.1796230]
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18. Maiquan Li, Weisu Huang, Fan Jie, Mengmeng Wang, Yongheng Zhong, Qi Chen, Baiyi Lu.  (2019)  Discovery of Keap1−Nrf2 small−molecule inhibitors from phytochemicals based on molecular docking.  FOOD AND CHEMICAL TOXICOLOGY,      [PMID:31412289] [10.1016/j.fct.2019.110758]
19. Dan Chen, Binglin Li, Bin Li, Xiaoli Zhang, Longhui Wei, Wenwen Zheng.  (2019)  Synthesis of vitamin E succinate catalyzed by nano-SiO2 immobilized DMAP derivative in mixed solvent system.  Green Processing and Synthesis,  (1): (667-676).  [PMID:] [10.1515/gps-2019-0037]
20. Lai Sisi, Wei Yanyan, Wu Quanwu, Zhou Kang, Liu Tuo, Zhang Yingfeng, Jiang Ning, Xiao Wen, Chen Junjie, Liu Qiuhong, Yu Yang.  (2019)  Liposomes for effective drug delivery to the ocular posterior chamber.  JOURNAL OF NANOBIOTECHNOLOGY,  17  (1): (1-12).  [PMID:31084611] [10.1186/s12951-019-0498-7]
21. Cheng Li, Xiao-Lin Qiu, Li-Xin Lu, Ya-Li Tang, Qing Long, Jin-Gui Dang.  (2019)  Preparation of low-density polyethylene film with quercetin and α-tocopherol loaded with mesoporous silica for synergetic-release antioxidant active packaging.  JOURNAL OF FOOD PROCESS ENGINEERING,  42  (5): (e13088).  [PMID:] [10.1111/jfpe.13088]
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