1-(Dimethylamino)-2-methylpropan-2-ol: Uses, Safety & Handling

1-(Dimethylamino)-2-methylpropan-2-ol is a bifunctional tertiary amino alcohol widely used as a reactive amine catalyst, pH modifier, and synthetic building block in academic and industrial research settings.

CAS Number

2212-32-0

Molecular Formula

C6H15NO

Molecular Weight

117.19 g/mol

Aladdin SKU

M710303

Functional Groups

Tertiary amine and tertiary alcohol

Physical State

Liquid at room temperature

Primary Application

Reactive amine catalyst, pH adjustment, organic synthesis intermediate

What Is 1-(Dimethylamino)-2-methylpropan-2-ol?

1-(Dimethylamino)-2-methylpropan-2-ol, also known as DMAMP, is a bifunctional organic compound bearing both a tertiary dimethylamino group and a tertiary hydroxyl group on adjacent carbon atoms. Its CAS number is 2212-32-0, and it has the molecular formula C₆H₁₅NO with a molecular weight of approximately 117.19 g/mol. The compound is a colorless to pale yellow liquid at room temperature with miscibility in water and common organic solvents, making it versatile for aqueous and non-aqueous research applications.

The dual functionality of DMAMP — nucleophilic nitrogen and hydroxyl group — underpins its utility both as a reactive catalyst and as a building block. It is catalogued under Aladdin Scientific SKU M710303 and is intended for research and development use.

Key Research Applications

1-(Dimethylamino)-2-methylpropan-2-ol serves several important roles in research and industrial chemistry:

• Reactive Amine Catalyst: DMAMP is widely employed as a reactive (non-fugitive) amine catalyst in polyurethane foam chemistry. Its hydroxyl group allows it to incorporate into the polymer matrix, reducing amine emissions compared with conventional tertiary amine catalysts.
• pH Modifier and Neutralizing Agent: The basic tertiary amine functionality makes DMAMP suitable for neutralizing acidic species in coating formulations, waterborne resins, and emulsion systems, improving dispersion stability.
• Organic Synthesis Intermediate: DMAMP is used as a chiral or achiral building block in the synthesis of pharmaceuticals, agrochemicals, and specialty materials, leveraging both its amine and alcohol reactivities for condensation, alkylation, or coordination chemistry.
• Ligand and Coordination Chemistry: The bifunctional N,O-donor character allows DMAMP to serve as a bidentate ligand in metal-coordination studies relevant to catalysis research.

Researchers should consult primary literature and safety data sheets to determine suitability for specific experimental protocols.

Safe Handling, Storage, and Disposal

As with all tertiary amine-containing reagents, appropriate precautions must be observed when working with 1-(Dimethylamino)-2-methylpropan-2-ol:

• Personal Protective Equipment (PPE): Wear chemical-resistant gloves, safety goggles, and a laboratory coat. Work in a well-ventilated area or fume hood to minimize inhalation of vapors.
• Skin and Eye Contact: The compound is corrosive to skin and eyes. In case of contact, flush immediately with copious amounts of water and seek medical attention if irritation persists.
• Storage: Store in a tightly sealed container in a cool, dry, well-ventilated area away from strong acids and oxidizing agents. Follow the temperature and humidity conditions stated on the product label and Safety Data Sheet (SDS).
• Disposal: Dispose of waste material in accordance with local, regional, and national regulations. Do not pour down drains. Consult your institution's environmental health and safety office for guidance.

Always refer to the current SDS provided by Aladdin Scientific before beginning experimental work with this reagent.

Ordering and Specifications

1-(Dimethylamino)-2-methylpropan-2-ol is available from Aladdin Scientific under SKU M710303. When placing an order, please note the following:

• Purity and Grade: Confirm the purity specification on the product page or Certificate of Analysis (CoA) prior to use in sensitive assays. Aladdin Scientific provides lot-specific CoAs upon request.
• Pack Sizes: Multiple pack sizes may be available to suit laboratory-scale and larger research needs. Contact Aladdin Scientific customer service for bulk pricing and availability.
• Lead Time and Shipping: Standard shipping conditions apply. Reagents are typically dispatched in compliance with applicable transport regulations for chemical substances. Check the product listing for current stock status.
• Returns and Quality: If you receive a product that does not meet stated specifications, contact Aladdin Scientific customer service with your order number and CoA for resolution in accordance with the returns and refunds policy.

Frequently asked questions

What is the CAS number and molecular formula of 1-(Dimethylamino)-2-methylpropan-2-ol?

The CAS number of 1-(Dimethylamino)-2-methylpropan-2-ol is 2212-32-0. Its molecular formula is C6H15NO, and its molecular weight is approximately 117.19 g/mol.

What are the main research applications of 1-(Dimethylamino)-2-methylpropan-2-ol?

It is primarily used as a reactive amine catalyst in polyurethane synthesis, a pH modifier and neutralizing agent in coating and resin formulations, an organic synthesis building block for pharmaceutical and agrochemical intermediates, and a bidentate N,O-donor ligand in coordination chemistry research.

How should 1-(Dimethylamino)-2-methylpropan-2-ol be stored?

Store the compound in a tightly sealed container in a cool, dry, and well-ventilated area, away from strong acids and oxidizing agents. Always refer to the current Safety Data Sheet (SDS) from Aladdin Scientific for precise storage temperature and humidity requirements.

Is a Certificate of Analysis available for Aladdin SKU M710303?

Yes. Aladdin Scientific provides lot-specific Certificates of Analysis (CoA) for M710303 upon request. Contact Aladdin Scientific customer service with your lot number to obtain the corresponding CoA.

What safety precautions should be taken when handling 1-(Dimethylamino)-2-methylpropan-2-ol?

Wear appropriate PPE including chemical-resistant gloves, safety goggles, and a lab coat. Handle the reagent in a fume hood to minimize vapor inhalation. In case of skin or eye contact, flush immediately with copious water. Dispose of waste according to applicable local regulations and consult the SDS for full hazard information.

References

1. Aladdin Scientific Product Page: 1-(Dimethylamino)-2-methylpropan-2-ol, SKU M710303.
2. PubChem Compound Summary for CAS 2212-32-0: 1-(Dimethylamino)-2-methylpropan-2-ol. National Library of Medicine.
3. Safety Data Sheet for 1-(Dimethylamino)-2-methylpropan-2-ol. Aladdin Scientific. (Consult current version on Aladdin website.)

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.