The GSK3 (glycogen synthase kinase 3) pathway is one of the most representative integrative signaling nodes within the cell. It does not belong to the typical linear "ligand-receptor-kinase" cascade, but is better understood as a constitutively poised regulatory hub whose activity is ...
Glucose metabolism is a core network for cellular energy conversion and carbon allocation, spanning glycolysis, gluconeogenesis, glycogen synthesis and breakdown, the pentose phosphate pathway, and the tricarboxylic acid (TCA) cycle.
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