One-carbon metabolism is not merely a matter of folate nutrition, but rather a metabolism-signaling integrated system jointly constituted by the folate cycle, the methionine cycle, and the transsulfuration pathway. On the one hand, this system sustains nucleic acid synthesis and methylation ...
Methionine (Met) is a sulfur-containing essential amino acid and a key node in protein synthesis, one-carbon metabolism and methylation networks, and redox homeostasis maintained via the transsulfuration pathway.
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