The kinin system is a major molecular network linking tissue injury, inflammatory responses, vascular reactivity, and regulation of neural excitability. Through coordinated control of kinin generation, receptor stratification, ion-channel sensitization, and amplification of neuroinflammation, ...
Nerve growth factor (NGF) is a prototypical member of the neurotrophin family. Through interactions with the high-affinity receptor TrkA (NTRK1) and the low-affinity receptor p75NTR (NGFR), NGF regulates neuronal survival, axonal growth, synaptic plasticity, and processes related to injury repair.
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