Cloruro de Fmoc-Lys(Me)₃-OH - ≥97% , CAS No.201004-29-7

CAS: 201004-29-7 Cat. No.: F168351 Peso molecular: 446.97

GRADE & PURITY ≥97%

Synonyms

(S)-5-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-carboxy-N,N,N-trimethylpentan-1-aminium chloride | Fmoc-Lys(Me3)-OH.nCl | F10733 | (S)-5-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-carboxy-N,N,N-trimethylpentan-1-aminium n-chloride | Fmoc-Lys(Me)3-O

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Descripción general

N-trimetil lisina protegida con Fmoc

Aplicación

El cloruro de Fmoc-Lys(Me)3-OH es uno de los reactivos N-terminal protegidos más utilizados en la síntesis de péptidos. Algunos de los ejemplos reportados son:

Síntesis de enlazadores peptídicos para conjugados anticuerpo monoclonal-auristatina F.

Preparación de reactivos multifuncionales con propiedades de ionización mejoradas para el análisis de la modificación de proteínas en células humanas y el perfilado dinámico de la lipidación de proteínas.

Ligación secuencial de péptidos para sintetizar histona H3 que contiene un residuo de trimetil lisina, con región de cola modificada.

Specifications

Sinónimos

(S)-5-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-carboxy-N, N, N-trimethylpentan-1-aminium chloride | Fmoc-Lys(Me3)-OH.nCl | F10733 | (S)-5-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-carboxy-N, N, N-trimethylpentan-1-aminium n-chloride | Fmoc-Lys(Me)3-O

Especificaciones y pureza

≥97%

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Pureza

≥97%

Nombres e identificadores

• Pubchem Sid: 488201478
• Sonrisas canónicas: C[N+](C)(C)CCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13.[Cl-]
• IUPAC Name: [(5S)-5-carboxy-5-(9H-fluoren-9-ylmethoxycarbonylamino)pentyl]-trimethylazanium;chloride
• InChIKey: XUJRNPVABVHOAJ-FTBISJDPSA-N
• INCHI: 1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1
• Isómeros SMILES: C[N+](C)(C)CCCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13.[Cl-]
• WGK Alemania: 3
• Peso molecular: 446.97
• Reaxy-Rn: 44419961
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=44419961&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Fluorenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Fluorenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Fluorenes
• Alternative Parents: Alpha amino acids and derivatives Medium-chain fatty acids Tetraalkylammonium salts Carbamate esters Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Organic chloride salts Hydrocarbon derivatives Carbonyl compounds Amines Organic cations
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Fluorene - Alpha-amino acid or derivatives - Medium-chain fatty acid - Fatty acid - Fatty acyl - Quaternary ammonium salt - Carbamic acid ester - Tetraalkylammonium salt - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic salt - Organic oxide - Amine - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organic chloride salt - Organic cation - Aromatic homopolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive
• Peso molecular: 447.000 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 10
• Exact Mass: 446.197 Da
• Monoisotopic Mass: 446.197 Da
• Topological Polar Surface Area: 75.600 Ų
• Heavy Atom Count: 31
• Formal Charge: 0
• Complexity: 566.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3