Folic acid PEG DSPE（FA-PEG-DSPE） - Moligand™, MW 5000 , CAS No.1236288-25-7

CAS: 1236288-25-7 Cat. No.: D659088 Peso molecular: 6226.473 PubChem CID: 156593841

GRADE & PURITY Moligand™, MW 5000

Synonyms

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000] (ammonium salt) | DSPE-PEG-Folate

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

DSPE-PEG-Folate (MW 5000) is a PEG derivative containing folic acid. DSPE-PEG-Folate (MW 5000) has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate (MW 5000) form micelles/lipid bilayer and can be used to targeted drug deli

Appearance:Solid

Biological Activity:DSPE-PEG-Folate (MW 5000) is a PEG derivative containing folic acid. DSPE-PEG-Folate (MW 5000) has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate (MW 5000) form micelles/lipid bilayer and can be used to targeted drug deli

Specifications

Sinónimos

1, 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000] (ammonium salt) | DSPE-PEG-Folate

Especificaciones y pureza

Moligand™, MW 5000

Mecanismos bioquímicos y fisiológicos

Folate receptors are cellular surface markers for numerous solid tumors.DSPE-PEG-folate (1, 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000]) incorporated into liposomes serves as a targeting ligand. Folate targeted drug d

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCCNC(=O)CCC(C(=O)O)NC(=O)C1=CC=C(C=C1)NCC2=NC3C(=O)NC(=N)N=C3N=C2)OC(=O)CCCCCCCCCCCCCCCCC.N
• IUPAC Name: azane;5-[2-[2-[2-[2,3-di(octadecanoyloxy)propoxy-hydroxyphosphoryl]oxyethylcarbamoyloxy]ethoxy]ethylamino]-2-[[4-[(2-imino-4-oxo-4aH-pteridin-6-yl)methylamino]benzoyl]amino]-5-oxopentanoic acid
• InChIKey: WXIKCKLNMQSVPC-UHFFFAOYSA-N
• INCHI: 1S/C65H108N9O16P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-57(76)87-49-54(90-58(77)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)50-89-91(83,84)88-44-42-68-65(82)86-46-45-85-43-41-67-56(75)40-39-55(63(80)81)72-61(78)51-35-37-52(38-36-51)69-47-53-48-70-60-59(71-53)62(79)74-64(66)73-60;/h35-38,48,54-55,59,69H,3-34,39-47,49-50H2,1-2H3,(H,67,75)(H,68,82)(H,72,78)(H,80,81)(H,83,84)(H2,66,74,79);1H3
• PubChem CID: 156593841
• Peso molecular: 6226.473

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (Need ultrasonic)
• Sensibilidad: Light sensitive；Heat sensitive

Referencias

1. Junhao Zhang, Nan Chen, Luping Ren, Lei Nie, Khaydar E. Yunusov, Uladzislau E. Aharodnikau, Sergey O. Solomevich, Yanfang Sun, Guohua Jiang.  (2024)  A red cell membrane-camouflaged nanoreactor for enhanced starvation/chemodynamic/ion interference therapy for breast cancer.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:39378701] [10.1016/j.colsurfb.2024.114293]