GRADE & PURITYValidated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.0.5 mg/mL
ExactAb™, Validated, 0.5 mg/mL ExactAb™,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C,Protected from light,Do not freeze Ships Wet ice,Do not freeze Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow Cytometry.
Specifications
Product Name
GITR/CD357 Rat mAb (PE) - Primary antibody, specific to GITR/CD357
Sinónimos
Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein |
Especificaciones y pureza
ExactAb™, Validated, 0.5 mg/mL
Mecanismos bioquímicos y fisiológicos
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Especies hospedadoras
Rat
Especificidad
GITR/CD357
Inmunógeno
Mouse CD25+ CD4+ T cells
Control positivo
Flow: C57BL/6 mouse splenocytes.
Conjugación
PE
Excitación (nm)
Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emisión (nm)
575nm
Ex/Em(nm)
Ex:565nm;Em:575nm
Grado
ExactAb™, Validated
Tipo de cadena ligera
lambda
Método de purificación
Protein G purified
Concentración
0.5 mg/mL
Almacenamiento y envío
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C,Protected from light,Do not freeze
Enviado en
Wet ice,Do not freeze
Estabilidad y almacenamiento
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Imágenes
GITR/CD357 Rat mAb (PE) (Ab190291) - Flow Cytometry Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (AF647) (Ab211659) and either Rat IgG (PE) (Ab180312; Left panel) or GITR/CD357 Rat mAb (PE) (Ab190291; Right panel) at 0.3 μg/test.
Aplicación
Aplicación
Dilution info
Flow Cytometry
≤1.0μg/ test
For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
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