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Synonyms
1H-Indole-3-carbonitrile,2-amino-6-[2-(3-fluorophenyl)ethenyl]-
Shipped In
Ice chest + Ice pads
Descripción general Information
GSK2643943A is an inhibitor ofdeubiquitylating enzyme (DUB)with IC50 of 160 nM forUSP20/Ub-Rho.
Targets
USP20/Ub-Rho (Cell-free assay) 160 nM
Specifications Sinónimos
1H-Indole-3-carbonitrile, 2-amino-6-[2-(3-fluorophenyl)ethenyl]-
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Propiedades del producto ALogP 3.571 Recuento HBD 2 Enlace rotable 2
Nombres e identificadores Pubchem Sid 504773490 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504773490 Sonrisas canónicas C1=CC(=CC(=C1)F)C=CC2=CC3=C(C=C2)C(=C(N3)N)C#N IUPAC Name 2-amino-6-[(E)-2-(3-fluorophenyl)ethenyl]-1H-indole-3-carbonitrile InChIKey CGXBPMZRTMXEIA-SNAWJCMRSA-N INCHI 1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+ Peso molecular 277.3 Reaxy-Rn 38910864 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38910864&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Estructura 3D Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solubility (25°C) In vitro DMSO: 55 mg/mL (198.34 mM); Ethanol: 8 mg/mL (28.84 mM); Water: Insoluble; DMSO (mg/ml) Solubilidad máxima 55 DMSO (mM) Solubilidad máxima 198.341146772449 Agua (mg/ml) Solubilidad máxima ＜1 Peso molecular 277.290 g/mol XLogP3 4.300 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 2 Exact Mass 277.102 Da Monoisotopic Mass 277.102 Da Topological Polar Surface Area 65.600 Ų Heavy Atom Count 21 Formal Charge 0 Complexity 441.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
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Reconstitution Calculator Reseñas
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