GSK2643943A - 10mM in DMSO , CAS No.2449301-27-1

CAS: 2449301-27-1 Cat. No.: G422830 Peso molecular: 277.3
Disponible para pedir
GRADE & PURITY 10mM in DMSO
Synonyms
1H-​Indole-​3-​carbonitrile,2-​amino-​6-​[2-​(3-​fluorophenyl)​ethenyl]​-
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
G422830-1ml
2

147,90US$

172,90US$
Guardar 25,00 US$ (14.46%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

GSK2643943A is an inhibitor ofdeubiquitylating enzyme (DUB)with IC50 of 160 nM forUSP20/Ub-Rho.

Targets

USP20/Ub-Rho (Cell-free assay) 160 nM

Specifications

Sinónimos
1H-​Indole-​3-​carbonitrile, 2-​amino-​6-​[2-​(3-​fluorophenyl)​ethenyl]​-
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Propiedades del producto
ALogP3.571
Recuento HBD2
Enlace rotable2
Nombres e identificadores
Sonrisas canónicasC1=CC(=CC(=C1)F)C=CC2=CC3=C(C=C2)C(=C(N3)N)C#N
IUPAC Name2-amino-6-[(E)-2-(3-fluorophenyl)ethenyl]-1H-indole-3-carbonitrile
InChIKeyCGXBPMZRTMXEIA-SNAWJCMRSA-N
INCHI1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+
Peso molecular 277.3
Reaxy-Rn 38910864
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38910864&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeFechaArticulo
H2401526Certificate of AnalysisJun 04, 2026 G422830
Propiedades químicas y físicas
DMSO (mg/ml) Solubilidad máxima55
DMSO (mM) Solubilidad máxima198.341146772449
Agua (mg/ml) Solubilidad máxima<1
Peso molecular277.290 g/mol
XLogP34.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass277.102 Da
Monoisotopic Mass277.102 Da
Topological Polar Surface Area65.600 Ų
Heavy Atom Count21
Formal Charge0
Complexity441.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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