Guanosine 5'-triphosphate trisodium salt hydrate - ≥95% , CAS No.36051-31-7

CAS: 36051-31-7 Cat. No.: G106782 Peso molecular: 589.13 Beilstein Registry Number: 3585677 Número EC: 252-847-2 PubChem CID: 135445727

GRADE & PURITY ≥95%

Synonyms

Guanosine 5'-triphosphate sodium salt hydrate, >=95% (HPLC) | trisodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] phosphate | Guanosine 5'-triphosphate sodium salt hydrate, >=9

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).

Specifications

Sinónimos

Guanosine 5'-triphosphate sodium salt hydrate, >=95% (HPLC) | trisodium;[[[(2R, 3S, 4R, 5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] phosphate | Guanosine 5'-triphosphate sodium salt hydrate, >=9

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

GTP can serve as a carrier for phosphatases and pyrophosphatases involved in channeling chemical energy into specific biosynthetic pathways. It activates G-proteins in signal transduction, which participate in various cellular processes such as proliferat

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504773326
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773326
• Sonrisas canónicas: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+].[Na+]
• IUPAC Name: trisodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] phosphate
• InChIKey: KZRMTEVIDYXWQW-CYCLDIHTSA-K
• INCHI: 1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1
• Isómeros SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+].[Na+]
• WGK Alemania: 3
• PubChem CID: 135445727
• Peso molecular: 589.13
• Beilstein: 3585677

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleotides
      • Subclass Purine ribonucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleotides
• Subclass: Purine ribonucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine ribonucleoside triphosphates
• Alternative Parents: Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-oxopurines Monosaccharide phosphates Hypoxanthines Pyrimidones Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Primary amines Organic sodium salts Organic zwitterions Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine ribonucleoside triphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Hypoxanthine - Monosaccharide phosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Pyrimidone - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Vinylogous amide - Azole - Heteroaromatic compound - Imidazole - Oxolane - Secondary alcohol - 1,2-diol - Organoheterocyclic compound - Organic alkali metal salt - Oxacycle - Azacycle - Organic sodium salt - Primary amine - Organic zwitterion - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organic salt - Amine - Organooxygen compound - Organic nitrogen compound - Alcohol - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine ribonucleoside triphosphates. These are purine ribobucleotides with a triphosphate group linked to the ribose moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: solubility H2O: 50 mg/mL
• Peso molecular: 589.130 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 7
• Exact Mass: 588.936 Da
• Monoisotopic Mass: 588.936 Da
• Topological Polar Surface Area: 303.000 Ų
• Heavy Atom Count: 35
• Formal Charge: 0
• Complexity: 907.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

Referencias

1. Liu Xianglan, Hu Jiaming, Wu Jiarui, Tian Yiru, Wang Jinbo, Wu Chunyan, Chen Qingfeng, Krall Leonard, He Yanping, Lu Qun.  (2025)  Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus.  Virology Journal,  22  (1): (1-14).  [PMID:40186285] [10.1186/s12985-025-02687-w]