Indotecan - ≥98% , CAS No.915303-09-2

CAS: 915303-09-2 Cat. No.: I412147 Peso molecular: 478.49 Número EC: 967-286-5
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
Indotecan(LMP400) | LMP400 | LMP-400 | LMP400; LMP-400; LMP 400 | HY-18351 | 3-[(Morpholine)-1-propyl]-5,3-dimethoxy-8,9-meth ylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinoline | AKOS040741879 | NSC-724998LMP-400 | UNII-BTA69L5M8D | BTA69L5M8D | NSC72499
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
I412147-1mg
3
99,90US$
5mg
I412147-5mg
3
259,90US$
10mg
I412147-10mg
3
439,90US$
25mg
I412147-25mg
3
739,90US$
50mg
I412147-50mg
2
1.079,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Indotecan (LMP-400, NSC-724998) is a potent topoisomerase 1(Top1) inhibitor with IC50 of 300 nM, 1200 nM, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.

Specifications

Sinónimos
Indotecan(LMP400) | LMP400 | LMP-400 | LMP400; LMP-400; LMP 400 | HY-18351 | 3-[(Morpholine)-1-propyl]-5, 3-dimethoxy-8, 9-meth ylenedioxy-5, 11-dioxo-11H-indeno[1, 2-c]isoquinoline | AKOS040741879 | NSC-724998LMP-400 | UNII-BTA69L5M8D | BTA69L5M8D | NSC72499
Especificaciones y pureza
≥98%
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Argon charged
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasCOC1=C(C=C2C(=C1)C3=C(C4=CC5=C(C=C4C3=O)OCO5)N(C2=O)CCCN6CCOCC6)OC
IUPAC Name15,16-dimethoxy-20-(3-morpholin-4-ylpropyl)-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione
InChIKeyFMFIFGLHVOZDEL-UHFFFAOYSA-N
INCHI1S/C26H26N2O7/c1-31-19-10-15-18(13-20(19)32-2)26(30)28(5-3-4-27-6-8-33-9-7-27)24-16-11-21-22(35-14-34-21)12-17(16)25(29)23(15)24/h10-13H,3-9,14H2,1-2H3
Isómeros SMILES COC1=C(C=C2C(=C1)C3=C(C4=CC5=C(C=C4C3=O)OCO5)N(C2=O)CCCN6CCOCC6)OC
Peso molecular 478.49
Reaxy-Rn 10618668
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10618668&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseIsoquinolines and derivatives
SubclassIsoquinolones and derivatives
Intermediate Tree Nodes Not available
Direct ParentIsoquinolones and derivatives
Alternative Parents Benzodioxoles  Anisoles  Aryl ketones  Pyridinones  Alkyl aryl ethers  Morpholines  Vinylogous amides  Heteroaromatic compounds  Trialkylamines  Lactams  Oxacyclic compounds  Acetals  Dialkyl ethers  Azacyclic compounds  Hydrocarbon derivatives  Organic oxides  Aldehydes  Organopnictogen compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Isoquinolone - Benzodioxole - Anisole - Aryl ketone - Alkyl aryl ether - Pyridinone - Morpholine - Oxazinane - Pyridine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Tertiary amine - Tertiary aliphatic amine - Lactam - Ketone - Azacycle - Oxacycle - Acetal - Dialkyl ether - Ether - Aldehyde - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Amine - Organic nitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as isoquinolones and derivatives. These are aromatic polycyclic compounds containing a ketone bearing isoquinoline moiety.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
TOP1 Tclin DNA topoisomerase I (7553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SN12C (47755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UACC-62 (47335 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HOP-62 (47048 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-435 (38290 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-539 (44845 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Leishmania infantum (5912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeFechaArticulo
I2404535Certificate of AnalysisJun 04, 2024 I412147
I2404536Certificate of AnalysisJun 04, 2024 I412147
I2404537Certificate of AnalysisJun 04, 2024 I412147
I2404538Certificate of AnalysisJun 04, 2024 I412147
I2404539Certificate of AnalysisJun 04, 2024 I412147
I2404540Certificate of AnalysisJun 04, 2024 I412147
I2404541Certificate of AnalysisJun 04, 2024 I412147
I2404564Certificate of AnalysisJun 04, 2024 I412147
I2404565Certificate of AnalysisJun 04, 2024 I412147
I2404566Certificate of AnalysisJun 04, 2024 I412147
Propiedades químicas y físicas
Peso molecular478.500 g/mol
XLogP32.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass478.174 Da
Monoisotopic Mass478.174 Da
Topological Polar Surface Area86.800 Ų
Heavy Atom Count35
Formal Charge0
Complexity872.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.