from bovine pancreas, ≥27 USP units/mg for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Insulin cattle (Insulin from bovine pancreas) are two-chain polypeptide hormones produced in pancreatic beta cells. Insulin cattle are used as growth factors in many mammalian cell culture systems
| Sonrisas canónicas | CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC1CSSCC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)C(C)C)CO)C)NC1=O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC4=CC=CC=C4)N)CO)CC5=CN=CN5)CC(C)C)C(C)C)CCC(=O)O)C)CC(C)C)CC6=CC=C(C=C6)O)CC(C)C)C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC7=CC=CC=C7)C(=O)NC(CC8=CC=CC=C8)C(=O)NC(CC9=CC=C(C=C9)O)C(=O)NC(C(C)O)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)NC(C)C(=O)O)C(=O)NC(CC(=O)N)C(=O)O)CC1=CC=C(C=C1)O)CC(=O)N)CCC(=O)O)CC(C)C)CCC(=O)N)CC1=CC=C(C=C1)O)CC(C)C)CO)NC(=O)CN |
|---|---|
| IUPAC Name | (4S)-4-[[2-[[(1R,6R,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,42R,47R,50S,53S,56S,59S,62S,65S,68S,71S,74R,77S,80S,83S,88R)-88-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[(2-aminoacetyl)amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]-6-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-4-oxobutanoyl]amino]-5-oxopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-47-[[(1S)-3-amino-1-carboxy-3-oxopropyl]carbamoyl]-53-(2-amino-2-oxoethyl)-62-(3-amino-3-oxopropyl)-24,56-bis(2-carboxyethyl)-12,71,80-tris(hydroxymethyl)-33,50,65-tris[(4-hydroxyphenyl)methyl]-15-(1H-imidazol-5-ylmethyl)-27,83-dimethyl-18,30,36,59,68-pentakis(2-methylpropyl)-7,10,13,16,19,22,25,28,31,34,37,40,49,52,55,58,61,64,67,70,73,76,79,82,85,87-hexacosaoxo-21,39,77-tri(propan-2-yl)-3,4,44,45,90,91-hexathia-8,11,14,17,20,23,26,29,32,35,38,41,48,51,54,57,60,63,66,69,72,75,78,81,84,86-hexacosazabicyclo[72.11.7]dononacontane-42-carbonyl]amino]acetyl]amino]-5-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[(2S)-2-[[(2S)-6-amino-1-[[(1S)-1-carboxyethyl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-oxopentanoic acid |
| InChIKey | IXIBAKNTJSCKJM-BUBXBXGNSA-N |
| INCHI | 1S/C254H377N65O75S6/c1-29-131(24)205(312-192(334)103-256)250(389)317-204(130(22)23)246(385)287-158(74-81-199(344)345)216(355)281-155(70-77-188(260)330)220(359)307-183-116-399-400-117-184-242(381)305-177(110-321)238(377)293-161(87-122(6)7)223(362)294-167(94-139-52-60-145(324)61-53-139)226(365)282-153(68-75-186(258)328)217(356)289-160(86-121(4)5)221(360)284-157(73-80-198(342)343)219(358)301-173(100-189(261)331)233(372)297-169(96-141-56-64-147(326)65-57-141)229(368)308-182(241(380)303-175(253(393)394)102-191(263)333)115-398-396-113-180(212(351)270-106-193(335)277-152(71-78-196(338)339)215(354)280-150(50-41-83-268-254(264)265)210(349)269-107-194(336)278-165(92-137-45-35-31-36-46-137)225(364)296-166(93-138-47-37-32-38-48-138)228(367)298-170(97-142-58-66-148(327)67-59-142)236(375)318-206(135(28)323)251(390)319-84-42-51-185(319)244(383)285-151(49-39-40-82-255)213(352)276-134(27)252(391)392)310-248(387)202(128(18)19)315-234(373)163(89-124(10)11)291-227(366)168(95-140-54-62-146(325)63-55-140)295-222(361)159(85-120(2)3)288-207(346)132(25)274-214(353)156(72-79-197(340)341)286-245(384)201(127(16)17)314-235(374)164(90-125(12)13)292-231(370)172(99-144-105-267-119-273-144)300-237(376)176(109-320)279-195(337)108-271-211(350)179(112-395-397-114-181(309-243(183)382)240(379)275-133(26)208(347)304-178(111-322)239(378)316-203(129(20)21)249(388)311-184)306-224(363)162(88-123(8)9)290-230(369)171(98-143-104-266-118-272-143)299-218(357)154(69-76-187(259)329)283-232(371)174(101-190(262)332)302-247(386)200(126(14)15)313-209(348)149(257)91-136-43-33-30-34-44-136/h30-38,43-48,52-67,104-105,118-135,149-185,200-206,320-327H,29,39-42,49-51,68-103,106-117,255-257H2,1-28H3,(H2,258,328)(H2,259,329)(H2,260,330)(H2,261,331)(H2,262,332)(H2,263,333)(H,266,272)(H,267,273)(H,269,349)(H,270,351)(H,271,350)(H,274,353)(H,275,379)(H,276,352)(H,277,335)(H,278,336)(H,279,337)(H,280,354)(H,281,355)(H,282,365)(H,283,371)(H,284,360)(H,285,383)(H,286,384)(H,287,385)(H,288,346)(H,289,356)(H,290,369)(H,291,366)(H,292,370)(H,293,377)(H,294,362)(H,295,361)(H,296,364)(H,297,372)(H,298,367)(H,299,357)(H,300,376)(H,301,358)(H,302,386)(H,303,380)(H,304,347)(H,305,381)(H,306,363)(H,307,359)(H,308,368)(H,309,382)(H,310,387)(H,311,388)(H,312,334)(H,313,348)(H,314,374)(H,315,373)(H,316,378)(H,317,389)(H,318,375)(H,338,339)(H,340,341)(H,342,343)(H,344,345)(H,391,392)(H,393,394)(H4,264,265,268)/t131-,132-,133-,134-,135+,149-,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,200-,201-,202-,203-,204-,205-,206-/m0/s1 |
| Isómeros SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)C(C)C)CO)C)NC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC4=CC=CC=C4)N)CO)CC5=CN=CN5)CC(C)C)C(C)C)CCC(=O)O)C)CC(C)C)CC6=CC=C(C=C6)O)CC(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC7=CC=CC=C7)C(=O)N[C@@H](CC8=CC=CC=C8)C(=O)N[C@@H](CC9=CC=C(C=C9)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)O)CC1=CC=C(C=C1)O)CC(=O)N)CCC(=O)O)CC(C)C)CCC(=O)N)CC1=CC=C(C=C1)O)CC(C)C)CO)NC(=O)CN |
| PubChem CID | 16131099 |
| Peso molecular | 5733.49 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 F2305311 | Certificate of Analysis | Mar 13, 2026 | I189675 |
| F2305315 | Certificate of Analysis | Mar 13, 2026 | I189675 |
| I2523435 | Certificate of Analysis | Sep 13, 2025 | I189675 |
| I2523434 | Certificate of Analysis | Sep 13, 2025 | I189675 |
| I2523433 | Certificate of Analysis | Sep 13, 2025 | I189675 |
| I2523432 | Certificate of Analysis | Sep 13, 2025 | I189675 |
| D2607038 | Certificate of Analysis | Sep 13, 2025 | I189675 |
| D2607037 | Certificate of Analysis | Sep 13, 2025 | I189675 |
| B2510402 | Certificate of Analysis | Jan 13, 2025 | I189675 |
| B2510404 | Certificate of Analysis | Jan 13, 2025 | I189675 |
| B2510403 | Certificate of Analysis | Jan 13, 2025 | I189675 |
| B2510401 | Certificate of Analysis | Jan 13, 2025 | I189675 |
| B2510400 | Certificate of Analysis | Jan 13, 2025 | I189675 |
| G2524042 | Certificate of Analysis | Jan 13, 2025 | I189675 |
| K2404405 | Certificate of Analysis | May 21, 2024 | I189675 |
| F2403060 | Certificate of Analysis | May 21, 2024 | I189675 |
| F2403062 | Certificate of Analysis | May 21, 2024 | I189675 |
| F2403063 | Certificate of Analysis | May 21, 2024 | I189675 |
| F2403061 | Certificate of Analysis | May 21, 2024 | I189675 |
| F2403064 | Certificate of Analysis | May 21, 2024 | I189675 |
| F2403065 | Certificate of Analysis | May 21, 2024 | I189675 |
| D2412317 | Certificate of Analysis | Mar 08, 2024 | I189675 |
| D2412316 | Certificate of Analysis | Mar 08, 2024 | I189675 |
| G2430047 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| B24261015 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| B24261028 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| B24261027 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| B24261018 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| B24261017 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| B24261016 | Certificate of Analysis | Jan 31, 2024 | I189675 |
| F2305318 | Certificate of Analysis | May 25, 2023 | I189675 |
| F2305312 | Certificate of Analysis | May 25, 2023 | I189675 |
| E2207037 | Certificate of Analysis | Mar 02, 2022 | I189675 |
| E2207036 | Certificate of Analysis | Mar 02, 2022 | I189675 |
| E2207035 | Certificate of Analysis | Mar 02, 2022 | I189675 |
| B2309031 | Certificate of Analysis | Mar 02, 2022 | I189675 |
| 1. Xiyuan Yi, Yong Luo, Qi Zhou, Jun Wang, Zengtao Yang. (2023) Visually controlled pulsatile release of insulin from chitosan poly-acrylic acid nanobubbles triggered by focused ultrasound. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:37482226] [10.1016/j.ijpharm.2023.123266] |
| 2. Xiang Chen, Haojie Yu, Li Wang, Di Shen, Yu Wang, Yichuan Hong. (2023) Glucose-Responsive Microneedle Patch With Variable Crosslinking Density and Flexible Core–Shell Structure for Insulin Delivery. Advanced Materials Technologies, 8 (13): (2202124). [PMID:] [10.1002/admt.202202124] |
| 3. Ming Tian, Chen Ning, Siyuan Peng, Deyu Li, Renyi Jin, Yang Zhang, Zhemin Liu, Haijin Mou, Changliang Zhu. (2023) High-Efficiency Fermentation of Nattokinase by Recombinant PSP2 Using Oyster Protein Hydrolysate as a Substrate. Foods, 12 (6): (1252). [PMID:36981178] [10.3390/foods12061252] |
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| 5. Haoran Cheng, Haishan Wu, Ting Guo, Hyun Jin Park, Jinglei Li. (2022) Zinc insulin hexamer loaded alginate zinc hydrogel: Preparation, characterization and in vivo hypoglycemic ability. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, [PMID:36087882] [10.1016/j.ejpb.2022.08.016] |
| 6. Ya Zhang, Qifang Wu, Jian Liu, Zhongshan Zhang, Xiaojing Ma, Yaoyue Zhang, Jiawen Zhu, Ronald W. Thring, Mingjiang Wu, Yitian Gao, Haibin Tong. (2022) Sulforaphane alleviates high fat diet-induced insulin resistance via AMPK/Nrf2/GPx4 axis. BIOMEDICINE & PHARMACOTHERAPY, [PMID:35709656] [10.1016/j.biopha.2022.113273] |
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| 9. Xu-Fan Wang, Yi-Fan Duan, Yue-Qian Zhu, Zi-Jing Liu, Yu-Chen Wu, Tian-Hao Liu, Ling Zhang, Jian-Feng Wei, Guo-Chang Liu. (2024) An Insulin-Modified pH-Responsive Nanopipette Based on Ion Current Rectification. SENSORS, 24 (13): (4264). [PMID:39001043] [10.3390/s24134264] |
| 10. Shengming Hua, Yujie Zhang, Yifei Zhu, Xin Fu, Lingtao Meng, Lihua Zhao, Lingming Kong, Shihui Pan, Yuju Che. (2024) Tunicate cellulose nanocrystals strengthened injectable stretchable hydrogel as multi-responsive enhanced antibacterial wound dressing for promoting diabetic wound healing. CARBOHYDRATE POLYMERS, [PMID:39174115] [10.1016/j.carbpol.2024.122426] |
| 11. Zhang Jie, Chen Weiwu, Zhang Chen, He Qian, Wang Xudong, Han Jiayu, Gao Peng, Wang Kunyu, Xie Haoze, Gao Feng, Guo Yining, Guo Wenhao, Jiang Haofei, Le Jing, Zang Ruichen, Mo Sisi, Fan Haobo, Zhu Xiaoxiao, Jiang Xinrong, Gao Fengbin, Yu Yanlan, Ding Guoqing, Chen Yicheng. (2025) Prostate Cancer Cells Secrete PD-1 in Exosomes to Enhance Myeloid-Derived Suppressor Cell Activity and Promote Tumor Immune Evasion. CANCER RESEARCH, [PMID:40698651] [10.1158/0008-5472.CAN-24-3748] |
| 12. Junling Zhu, Rilian Lai, Qin Zheng, Shuying Huang, Shenghua Hu, Zhangfei Xu, Huixia Sun. (2025) Calycosin improves insulin resistance by regulating the hsa-miR-324-3p/AKT pathway to inhibit FOXO3a nuclear transfer. XENOBIOTICA, [PMID:40924558] [10.1080/00498254.2025.2558648] |
| 13. An-Qi Zhu, Ning Luo, Xiao-Ting Zhou, Min Yuan, Chu-Mei Zhang, Tian-Ling Pan, Kun-Ping Li. (2024) Transcriptomic insights into the lipotoxicity of high-fat high-fructose diet in rat and mouse. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, [PMID:38527560] [10.1016/j.jnutbio.2024.109626] |
| 14. Yujie Zhang, Renling Lu, Ming Chen, Shouyong Zhou, Dabing Zhang, Haifeng Han, Mingliang Zhang, Hongdeng Qiu. (2020) A highly efficient acyl-transfer approach to urea-functionalized silanes and their immobilization onto silica gel as stationary phases for liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:32797845] [10.1016/j.chroma.2020.461366] |
| 15. Chunting Du, Tao Wang, Dandan Li, Xiaohu Luo, Jiali Xing, Ren Wang, Hao Zhang. (2025) Preparation and characterization of porous starch-based microcapsules loaded with insulin nanoparticles for controllable releasing properties. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.106728] |
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| 17. Yu Wang, Haojie Yu, Li Wang, Lei Zhang, Jian Hu, Jingyi Feng, Zheng Deng, Chang Chen. (2025) A two-birds-with-one-stone polysaccharide-based microneedle therapy: Prolonged glycemic regulation and accelerated diabetic wound healing. CARBOHYDRATE POLYMERS, [PMID:41320412] [10.1016/j.carbpol.2025.124653] |
| 18. Yecheng Gao, Anqi Zhu, Jingjin Li, Hualin Liu, Xiaomin Li, Heping Zhang. (2025) Lactiplantibacillus plantarum Attenuates Diet-Induced Obesity and Insulin Resistance Through Gut Microbiota-Driven PPAR/PI3K-Axis Modulation. Microbial Biotechnology, 18 (11): (e70227). [PMID:41159770] [10.1111/1751-7915.70227] |
| 19. Minghui Kong, Haixia Yang, Daidi Fan, Jianjun Deng. (2025) pH-Responsive Sodium Alginate Micro-Nano Hydrogels for Oral Insulin Delivery: Enhancing Therapeutic Efficacy and Reducing Hypoglycemic Risk. Food Frontiers, [PMID:] [10.1002/fft2.70187] |
| 20. Biying Zhang, Taoxun Zhou, Runxin Zhu, Peixi Qin, Juncheng Li, Chunqun Wang, Hui Liu, Min Hu. (2025) Aptazyme-mediated gene regulation in Strongyloides stercoralis for functional studies of insulin receptor isoform specificity. PLoS Pathogens, 21 (12): (e1013774). [PMID:41406115] [10.1371/journal.ppat.1013774] |
| 21. Md. Fardin Khan, Luyong Zhang, Dongyan Qiang, Zhenhai Zhang, Huixia Lv. (2026) A self-healing, pH/glucose-responsive carboxymethyl chitosan and oxidized bacterial nanocellulose hydrogel for insulin and taurine delivery in diabetic wound healing. CARBOHYDRATE POLYMERS, [PMID:] [10.1016/j.carbpol.2026.125133] |
