Receptor nuclear ror-beta (RORB)

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  1. SR1001, Agonist of RAR-related orphan receptor-α;Agonist of RAR-related orphan receptor-γ
    CAS: 1335106-03-0 Número EC: 802-874-6 PubChem CID: 44241473 Formula: C15H13F6N3O4S2 Peso molecular: 477.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: S275957
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    Nombre IUPAC
    N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
    SMILES
    CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
    InChIKey
    OZBSSKGBKHOLGA-UHFFFAOYSA-N
    InChI
    1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)
    Sinónimos
    A13193 | BS-14916 | HY-13421 | BDBM50444338 | SR-03000001001-1 | SR1001 | SR-1001 | DTXSID801348120 | N-(5-(N-(4-(1,1...
  2. SR3335
    CAS: 293753-05-6 PubChem CID: 2360837 Formula: C13H9F6NO3S2 Peso molecular: 405.34
    En Stock Articulo #: S125917
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    Nombre IUPAC
    N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide
    SMILES
    C1=CSC(=C1)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
    InChIKey
    LZWUNZRMANFRAO-UHFFFAOYSA-N
    InChI
    1S/C13H9F6NO3S2/c14-12(15,16)11(21,13(17,18)19)8-3-5-9(6-4-8)20-25(22,23)10-2-1-7-24-10/h1-7,20-21H
    Sinónimos
    s2969 | N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)thiophene-2-sulfonamide | N-{4-[2,2,2-trifluoro-1-hy...
  3. SR 2211, Agonist of RAR-related orphan receptor-γ
    CAS: 1359164-11-6 Número EC: 809-210-4 PubChem CID: 51035449 Formula: C26H24F7N3O Peso molecular: 527.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Fuera de Stock Articulo #: S288529
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    Nombre IUPAC
    1,1,1,3,3,3-hexafluoro-2-[3-fluoro-4-[4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol
    SMILES
    C1CN(CCN1CC2=CC=C(C=C2)C3=C(C=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O)F)CC4=CC=NC=C4
    InChIKey
    KVHKWAZUPPBMLL-UHFFFAOYSA-N
    InChI
    1S/C26H24F7N3O/c27-23-15-21(24(37,25(28,29)30)26(31,32)33)5-6-22(23)20-3-1-18(2-4-20)16-35-11-13-36(14-12-35)17-19-7-9-34-10-8-19/h1-10,15,37H,11-14,1show more
    Sinónimos
    SR-03000002211-1 | MLS004256334 | 2-Fluoro-4'-[[4-(4-pyridinylMethyl)-1-piperazinyl]Methyl]-alpha,alpha-bis(trifluoro...
  4. (±)-ML 209
    CAS: 1334526-14-5 Formula: C25H31NO6 Peso molecular: 441.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    En Stock Articulo #: M287706
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    Nombre IUPAC
    3-(1,3-benzodioxol-5-yl)-1-[(3S,5R)-3,5-dimethylpiperidin-1-yl]-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one
    SMILES
    CC1CC(CN(C1)C(=O)CC(C2=CC3=C(C=C2)OCO3)C4=C(C=C(C=C4OC)OC)O)C
    InChIKey
    YEKVAIMYYCZDLI-MCPYQZEQSA-N
    InChI
    1S/C25H31NO6/c1-15-7-16(2)13-26(12-15)24(28)11-19(17-5-6-21-22(8-17)32-14-31-21)25-20(27)9-18(29-3)10-23(25)30-4/h5-6,8-10,15-16,19,27H,7,11-14H2,1-4Hshow more
    Sinónimos
    3-(1,3-Benzodioxol-5-yl)-1-(cis-3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone
  5. SR3335
    CAS: 293753-05-6 PubChem CID: 2360837 Formula: C13H9F6NO3S2 Peso molecular: 405.34
    10mM in DMSO
    En Stock Articulo #: S423039
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    Identificadores técnicos
    Nombre IUPAC
    N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide
    SMILES
    C1=CSC(=C1)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
    InChIKey
    LZWUNZRMANFRAO-UHFFFAOYSA-N
    InChI
    1S/C13H9F6NO3S2/c14-12(15,16)11(21,13(17,18)19)8-3-5-9(6-4-8)20-25(22,23)10-2-1-7-24-10/h1-7,20-21H
    Sinónimos
    293753-05-6|SR3335|SR-3335|N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-thiophenesulfonamide|N-[4-(1,1...
  6. SR1001, Agonist of RAR-related orphan receptor-α;Agonist of RAR-related orphan receptor-γ
    CAS: 1335106-03-0 Número EC: 802-874-6 PubChem CID: 44241473 Formula: C15H13F6N3O4S2 Peso molecular: 477.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: S421269
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    Identificadores técnicos
    Nombre IUPAC
    N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
    SMILES
    CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
    InChIKey
    OZBSSKGBKHOLGA-UHFFFAOYSA-N
    InChI
    1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)
    Sinónimos
    A13193 | BS-14916 | HY-13421 | BDBM50444338 | SR-03000001001-1 | SR1001 | SR-1001 | DTXSID801348120 | N-(5-(N-(4-(1,1...
  7. AZD0284, Agonist of RAR-related orphan receptor-γ
    CAS: 2101291-07-8 PubChem CID: 129205086 Formula: C21H18F6N2O5S Peso molecular: 524.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: A607852
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    Nombre IUPAC
    (1R)-2-acetyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-5-methylsulfonyl-1,3-dihydroisoindole-1-carboxamide
    SMILES
    CC(=O)N1CC2=C(C1C(=O)NC3=CC=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O)C=CC(=C2)S(=O)(=O)C
    InChIKey
    QYYZXEPEVBXNNA-QGZVFWFLSA-N
    InChI
    1S/C21H18F6N2O5S/c1-11(30)29-10-12-9-15(35(2,33)34)7-8-16(12)17(29)18(31)28-14-5-3-13(4-6-14)19(32,20(22,23)24)21(25,26)27/h3-9,17,32H,10H2,1-2H3,(H,2show more
    Sinónimos
    HY-120384 | compound 20 [PMID: 34464130] | AZD0284 | AZD-0284 | GTPL11711 | 5G4XF6VU2Y | BDBM50575029 | VCH | 1H-Isoi...
  8. [(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-(4-hydroxy-1,1-dioxothian-4-yl)methanone, Agonist of RAR-related orphan receptor-γ
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: A609113
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    Nombre IUPAC
    [(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-(4-hydroxy-1,1-dioxothian-4show more
    SMILES
    Fc1ccc(cc1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)C(=O)C1(O)CCS(=O)(=O)CC1
    InChIKey
    ONXFNBOZJKXCNC-ZJSXRUAMSA-N
    InChI
    1S/C27H25F8NO6S2/c28-18-3-5-19(6-4-18)44(41,42)24-9-12-36(22(37)23(38)10-13-43(39,40)14-11-23)21(24)8-1-16-15-17(2-7-20(16)24)25(29,26(30,31)32)27(33,show more
    Sinónimos
    example 69 [WO2016179460A1] | compound 32
  9. GNE-3500, Agonist of RAR-related orphan receptor-γ
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: G610613
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    Nombre IUPAC
    1-[4-[3-fluoro-4-[[(3S,6R)-3-methyl-1,1-dioxo-6-phenylthiazinan-2-yl]methyl]phenyl]piperazin-1-yl]ethanone
    SMILES
    C[C@H]1CC[C@@H](S(=O)(=O)N1Cc1ccc(cc1F)N1CCN(CC1)C(=O)C)c1ccccc1
    InChIKey
    WLCIIQPUMOJJOF-MHECFPHRSA-N
    InChI
    1S/C24H30FN3O3S/c1-18-8-11-24(20-6-4-3-5-7-20)32(30,31)28(18)17-21-9-10-22(16-23(21)25)27-14-12-26(13-15-27)19(2)29/h3-7,9-10,16,18,24H,8,11-15,17H2,1show more
  10. S18-000003
    CAS: 2068119-11-7 PubChem CID: 137796283 Formula: C26H25F3N2O4S Peso molecular: 518.55
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: S648830
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    Nombre IUPAC
    N-(2,4-difluorophenyl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]-2-fluorophenyl]-2-methylpropanamide
    SMILES
    CCS(=O)(=O)C1=CC=C(C=C1)CC(=O)NC2=CC(=C(C=C2)C(C)(C)C(=O)NC3=C(C=C(C=C3)F)F)F
    InChIKey
    DZUAIKQCQQBQJM-UHFFFAOYSA-N
    InChI
    1S/C26H25F3N2O4S/c1-4-36(34,35)19-9-5-16(6-10-19)13-24(32)30-18-8-11-20(21(28)15-18)26(2,3)25(33)31-23-12-7-17(27)14-22(23)29/h5-12,14-15H,4,13H2,1-3Hshow more
    Sinónimos
    N-(2,4-Difluorophenyl)-2-(4-(2-(4-(ethylsulfonyl)phenyl)acetamido)-2-fluorophenyl)-2-methylpropanamide
  11. GNE-6468
    CAS: 1677668-27-7 PubChem CID: 117964975 Formula: C23H16ClN3O4 Peso molecular: 433.84
    Fuera de Stock Articulo #: G651767
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    Nombre IUPAC
    4-[6-(2-chloro-6-cyclopropylbenzoyl)imidazo[1,5-a]pyrimidin-8-yl]-2-hydroxybenzoic acid
    SMILES
    C1CC1C2=C(C(=CC=C2)Cl)C(=O)C3=NC(=C4N3C=CC=N4)C5=CC(=C(C=C5)C(=O)O)O
    InChIKey
    GIYKJPISDNWSJD-UHFFFAOYSA-N
    InChI
    1S/C23H16ClN3O4/c24-16-4-1-3-14(12-5-6-12)18(16)20(29)22-26-19(21-25-9-2-10-27(21)22)13-7-8-15(23(30)31)17(28)11-13/h1-4,7-12,28H,5-6H2,(H,30,31)
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