Proteína quinasa 3 asociada a la muerte (DAPK3)

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  1. Pyridone 6, Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3;Inhibitor of tyrosine kinase 2
    CAS: 457081-03-7 PubChem CID: 5494425 Formula: C18H16FN3O Peso molecular: 309.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: P287366
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    Nombre IUPAC
    4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11.4.0.02,6.07,12]heptadeca-1(13),2(6),4,7(12),8,14,16-heptaen-11-one
    SMILES
    CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O
    InChIKey
    VNDWQCSOSCCWIP-UHFFFAOYSA-N
    InChI
    1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
    Sinónimos
    CHEBI:195037 | DTXSID40420526 | EX-A123 | LDX3F0CCST | SCHEMBL904545 | HMS3244K22 | JAK Inhibitor I; 2-(1,1-Dimethyle...
  2. MK2-IN-3, Inhibitor of MAPK activated protein kinase 2;Inhibitor of MAPK activated protein kinase 3;Inhibitor of MAPK activated protein kinase 5
    CAS: 724711-21-1 Formula: C21H16N4O Peso molecular: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: M333061
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    Nombre IUPAC
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
    SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
    InChIKey
    OWFLADWRSCINST-UHFFFAOYSA-N
    InChI
    1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)
    Sinónimos
    1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one | MK2 Inhibitor III
  3. Fedratinib (SAR302503, TG101348), Tyrosine-protein kinase JAK2 inhibitor
    CAS: 936091-26-8 Número EC: 829-304-9 PubChem CID: 16722836 Formula: C27H36N6O3S Peso molecular: 524.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: T126330
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    Nombre IUPAC
    N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
    SMILES
    CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
    InChIKey
    JOOXLOJCABQBSG-UHFFFAOYSA-N
    InChI
    1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,show more
    Sinónimos
    7.ALPHA.-METHYLNORETHINDRONE | FEDRATINIB [WHO-DD] | NSC800099 | NSC-800099 | N-Tert-butyl-3-(5-methyl-2-(4-(2-pyrrol...
  4. Fedratinib (TG101348), Tyrosine-protein kinase JAK2 inhibitor
    CAS: 936091-26-8 Número EC: 829-304-9 PubChem CID: 16722836 Formula: C27H36N6O3S Peso molecular: 524.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: F408078
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    Sinónimos
    SAR302503 | N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
  5. HS 38
    CAS: 1030203-81-6 Número EC: 808-443-9 Formula: C14H12CIN5O2S Peso molecular: 349.8
    En Stock Articulo #: H287038
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    Nombre IUPAC
    2-[[1-(3-chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]propanamide
    SMILES
    CC(C(=O)N)SC1=NC2=C(C=NN2C3=CC(=CC=C3)Cl)C(=O)N1
    InChIKey
    NASYEGAVCTZSDO-UHFFFAOYSA-N
    InChI
    1S/C14H12ClN5O2S/c1-7(11(16)21)23-14-18-12-10(13(22)19-14)6-17-20(12)9-4-2-3-8(15)5-9/h2-7H,1H3,(H2,16,21)(H,18,19,22)
    Sinónimos
    Z247384094 | 2-[[1-(3-chlorophenyl)-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]propanamide | 1030203-81-6 | AKOS...
  6. MK2 Inhibitor III, Inhibitor of MAPK activated protein kinase 2;Inhibitor of MAPK activated protein kinase 3;Inhibitor of MAPK activated protein kinase 5
    CAS: 724711-21-1 Formula: C21H16N4O Peso molecular: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: M425672
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    Nombre IUPAC
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
    SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
    InChIKey
    OWFLADWRSCINST-UHFFFAOYSA-N
    InChI
    1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)
    Sinónimos
    1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one
  7. 2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one, Inhibitor of MAPK activated protein kinase 2;Inhibitor of MAPK activated protein kinase 3;Inhibitor of MAPK activated protein kinase 5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: Q608769
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    Nombre IUPAC
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
    SMILES
    O=C1NCCc2c1cc([nH]2)c1ccnc(c1)c1cnc2c(c1)cccc2
    InChIKey
    OWFLADWRSCINST-UHFFFAOYSA-N
    InChI
    1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)
    Sinónimos
    compound 16
  8. HS38
    CAS: 1030203-81-6 Número EC: 808-443-9 Formula: C14H12CIN5O2S Peso molecular: 349.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Fuera de Stock Articulo #: H1498320
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  9. Pyridone 6
    CAS: 457081-03-7 PubChem CID: 5494425 Formula: C18H16FN3O Peso molecular: 309.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Fuera de Stock Articulo #: P1497038
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  10. 2-(2-Phenylethenyl)-4-(pyridin-3-ylmethylidene)-4,5-dihydro-1,3-oxazol-5-one
    CAS: 2439180-90-0 Formula: C17H12N2O2 Peso molecular: 276.290
    Fuera de Stock Articulo #: P984661
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    Nombre IUPAC
    (4Z)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
    SMILES
    C1=CC=C(C=C1)/C=C/C2=N/C(=C\C3=CN=CC=C3)/C(=O)O2
    InChIKey
    GFGMISOSPOPSHN-NOCYUORASA-N
    InChI
    1S/C17H12N2O2/c20-17-15(11-14-7-4-10-18-12-14)19-16(21-17)9-8-13-5-2-1-3-6-13/h1-12H/b9-8+,15-11-
  11. A-216546 free base
    CAS: 212481-66-8 Número EC: 860-920-0 Formula: C30H48N2O6 Peso molecular: 532.700
    Fuera de Stock Articulo #: A1007580
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    Nombre IUPAC
    (2S,3R,4S)-1-[2-(dibutylamino)-2-oxoethyl]-2-(2,2-dimethylpentyl)-4-(7-methoxy-1,3-benzodioxol-5-yl)pyrrolidine-3-carboxylic acid
    SMILES
    CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(=O)O)C2=CC3=C(C(=C2)OC)OCO3
    InChIKey
    OAEWNSKRLBVVBV-QSEAXJEQSA-N
    InChI
    1S/C30H48N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h15-16,22-23,27H,7-14show more
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