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Proteína quinasa activada por mitógenos mlt (ZAK)

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  1. Vemurafenib (PLX4032, RG7204), Serine/threonine-protein kinase B-raf inhibitor
    Lista de deseos Añadir para comparar
    Vemurafenib (PLX4032, RG7204), Serine/threonine-protein kinase B-raf inhibitor
    CAS: 918504-65-1 Número EC: 850-250-7 PubChem CID: 42611257 Formula: C23H18ClF2N3O3S Peso molecular: 489.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: V127521
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    Nombre IUPAC
    N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide
    SMILES
    CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F
    InChIKey
    GPXBXXGIAQBQNI-UHFFFAOYSA-N
    InChI
    1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,show more
    Sinónimos
    1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)- | 207SMY...
  2. LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    Lista de deseos Añadir para comparar
    LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 1454682-72-4 Formula: C23H29FN6O Peso molecular: 424.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: L288815
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    Nombre IUPAC
    1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea
    SMILES
    CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F
    InChIKey
    HHCBMISMPSAZBF-UHFFFAOYSA-N
    InChI
    1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,2show more
    Sinónimos
    1454682-72-4 | C72761 | Pan-raf inhibitor ly3009120 | SCHEMBL15241297 | 1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-...
  3. LY364947, Inhibitor of transforming growth factor beta receptor 1
    Lista de deseos Añadir para comparar
    LY364947, Inhibitor of transforming growth factor beta receptor 1
    CAS: 396129-53-6 Número EC: 636-801-2 Formula: C17H12N4 Peso molecular: 272.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: L129343
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    Nombre IUPAC
    4-(5-pyridin-2-yl-1H-pyrazol-4-yl)quinoline
    SMILES
    C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
    InChIKey
    IBCXZJCWDGCXQT-UHFFFAOYSA-N
    InChI
    1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21)
    Sinónimos
    SB19489 | 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE | s2805 | HMS3229M09 | PY1 | 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl...
  4. Apatinib
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    Apatinib
    CAS: 811803-05-1 Número EC: 881-354-0 Formula: C24H23N5O Peso molecular: 397.47
    10mM in DMSO
    En Stock Articulo #: A426102
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    Nombre IUPAC
    N-[4-(1-cyanocyclopentyl)phenyl]-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide
    SMILES
    C1CCC(C1)(C#N)C2=CC=C(C=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4
    InChIKey
    WPEWQEMJFLWMLV-UHFFFAOYSA-N
    InChI
    1S/C24H23N5O/c25-17-24(11-1-2-12-24)19-5-7-20(8-6-19)29-23(30)21-4-3-13-27-22(21)28-16-18-9-14-26-15-10-18/h3-10,13-15H,1-2,11-12,16H2,(H,27,28)(H,29,show more
    Sinónimos
    AKOS024464453 | N-(4-(1-cyanocyclopentyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide | BA175030 | HY-13342A | Apa...
  5. LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    Lista de deseos Añadir para comparar
    LY 3009120, Inhibitor of A-Raf proto-oncogene; serine/threonine kinase;Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 1454682-72-4 Formula: C23H29FN6O Peso molecular: 424.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    En Stock Articulo #: L421677
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Nombre IUPAC
    1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea
    SMILES
    CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F
    InChIKey
    HHCBMISMPSAZBF-UHFFFAOYSA-N
    InChI
    1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,2show more
    Sinónimos
    LY3009120|1454682-72-4|LY-3009120|DP-4978|1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrid...
  6. LY364947, Inhibitor of transforming growth factor beta receptor 1
    Lista de deseos Añadir para comparar
    LY364947, Inhibitor of transforming growth factor beta receptor 1
    CAS: 396129-53-6 Número EC: 636-801-2 Formula: C17H12N4 Peso molecular: 272.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    En Stock Articulo #: L423823
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Nombre IUPAC
    4-(5-pyridin-2-yl-1H-pyrazol-4-yl)quinoline
    SMILES
    C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
    InChIKey
    IBCXZJCWDGCXQT-UHFFFAOYSA-N
    InChI
    1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21)
    Sinónimos
    SB19489 | 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE | s2805 | HMS3229M09 | PY1 | 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl...
  7. Vemurafenib (PLX4032), Serine/threonine-protein kinase B-raf inhibitor
    Lista de deseos Añadir para comparar
    Vemurafenib (PLX4032), Serine/threonine-protein kinase B-raf inhibitor
    CAS: 918504-65-1 Número EC: 850-250-7 PubChem CID: 42611257 Formula: C23H18ClF2N3O3S Peso molecular: 489.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: V409259
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Sinónimos
    RG7204, RO5185426
  8. no_selection
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    3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)benzimidazol-1-yl]propan-1-ol, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2;Inhibitor of ZAK sterile alpha motif and leucine zipper containing kinase AZK
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: P608741
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Nombre IUPAC
    3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)benzimidazol-1-yl]propan-1-ol
    SMILES
    OCCCn1cnc2c1cc(cc2)c1c2CCCn2nc1c1ccccn1
    InChIKey
    SYCWRTUPLPDKDX-UHFFFAOYSA-N
    InChI
    1S/C21H21N5O/c27-12-4-10-25-14-23-16-8-7-15(13-19(16)25)20-18-6-3-11-26(18)24-21(20)17-5-1-2-9-22-17/h1-2,5,7-9,13-14,27H,3-4,6,10-12H2
    Sinónimos
    compound 15b
  9. SR-318
    Lista de deseos Añadir para comparar
    SR-318
    CAS: 2413286-32-3 PubChem CID: 139030333 Formula: C27H33N5O2 Peso molecular: 459.58
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: S649687
    Vista del artículo
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    Identificadores técnicos
    Nombre IUPAC
    5-amino-N-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenylpyrazole-4-carboxamide
    SMILES
    C1CCC(CC1)CCCNC(=O)C2=CC=C(C=C2)CNC(=O)C3=C(N(N=C3)C4=CC=CC=C4)N
    InChIKey
    HXNUFFCHRIWTRZ-UHFFFAOYSA-N
    InChI
    1S/C27H33N5O2/c28-25-24(19-31-32(25)23-11-5-2-6-12-23)27(34)30-18-21-13-15-22(16-14-21)26(33)29-17-7-10-20-8-3-1-4-9-20/h2,5-6,11-16,19-20H,1,3-4,7-10show more
  10. LY-364947
    Lista de deseos Añadir para comparar
    LY-364947
    CAS: 396129-53-6 Número EC: 636-801-2 Formula: C17H12N4 Peso molecular: 272.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Fuera de Stock Articulo #: L1496327
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    Identificadores técnicos
  11. LY3009120
    Lista de deseos Añadir para comparar
    LY3009120
    CAS: 1454682-72-4 Formula: C23H29FN6O Peso molecular: 424.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Fuera de Stock Articulo #: L1495707
    Vista del artículo
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