Dihidroorotato deshidrogenasa

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  1. Leflunomide, Dihydroorotate dehydrogenase inhibitor
    CAS: 75706-12-6 Número EC: 616-254-6 Formula: C12H9F3N2O2 Peso molecular: 270.21
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: L129518
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    Nombre IUPAC
    5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
    SMILES
    CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
    InChIKey
    VHOGYURTWQBHIL-UHFFFAOYSA-N
    InChI
    1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
    Sinónimos
    HWA486 | RS-34821 | L 5025 | leflunomide | SU 101 | UNII-G162GK9U4W | HMS2235C07 | HMS3371F21 | lefunamide | 5-Methyl...
  2. Tenovin-1
    CAS: 380315-80-0 PubChem CID: 1013376 Formula: C20H23N3O2S Peso molecular: 369.48
    En Stock Articulo #: T125146
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    Nombre IUPAC
    N-[(4-acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide
    SMILES
    CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C
    InChIKey
    WOWJIWFCOPZFGV-UHFFFAOYSA-N
    InChI
    1S/C20H23N3O2S/c1-13(24)21-16-9-11-17(12-10-16)22-19(26)23-18(25)14-5-7-15(8-6-14)20(2,3)4/h5-12H,1-4H3,(H,21,24)(H2,22,23,25,26)
    Sinónimos
    Q27166342 | SR-01000946350-1 | CCG-208685 | N-(4-acetamidophenylcarbamothioyl)-4-tert-butylbenzamide | HY-13423 | SW1...
  3. Tenovin-6
    CAS: 1011557-82-6 PubChem CID: 24772043 Formula: C25H34N4O2S Peso molecular: 454.6
    En Stock Articulo #: T338048
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    Nombre IUPAC
    4-tert-butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide
    SMILES
    CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C
    InChIKey
    BVJSXSQRIUSRCO-UHFFFAOYSA-N
    InChI
    1S/C25H34N4O2S/c1-25(2,3)19-11-9-18(10-12-19)23(31)28-24(32)27-21-15-13-20(14-16-21)26-22(30)8-6-7-17-29(4)5/h9-16H,6-8,17H2,1-5H3,(H,26,30)(H2,27,28,show more
    Sinónimos
    1011557-82-6 | SR-01000946351 | EX-A350 | AS-16762 | 4-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)butanoicacid | SR-0100094...
  4. Brequinar (DUP785), Dihydroorotate dehydrogenase inhibitor
    CAS: 96187-53-0 Formula: C23H15F2NO2 Peso molecular: 375.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: B405327
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    6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid
    SMILES
    CC1=C(C2=C(C=CC(=C2)F)N=C1C3=CC=C(C=C3)C4=CC=CC=C4F)C(=O)O
    InChIKey
    PHEZJEYUWHETKO-UHFFFAOYSA-N
    InChI
    1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28)
    Sinónimos
    BCP06006 | brequinarum | EX-A1515 | 2-(2'-Fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinolinecarboxylic acid | 4...
  5. Lapachol
    CAS: 84-79-7 Número EC: 201-563-7 Formula: C15H14O3 Peso molecular: 242.27
    En Stock Articulo #: L137385
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    Nombre IUPAC
    4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione
    SMILES
    CC(=CCC1=C(C2=CC=CC=C2C(=O)C1=O)O)C
    InChIKey
    CWPGNVFCJOPXFB-UHFFFAOYSA-N
    InChI
    1S/C15H14O3/c1-9(2)7-8-12-13(16)10-5-3-4-6-11(10)14(17)15(12)18/h3-7,16H,8H2,1-2H3
    Sinónimos
    NINDS_000594 | SPBio_001341 | Surinam greenheart wood | Taiguic acid | NCGC00094931-01 | HMS3869D03 | Spectrum3_00076...
  6. AG-636
    CAS: 1623416-31-8 Formula: C21H17N3O2 Peso molecular: 343.38
    En Stock Articulo #: A414482
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    Nombre IUPAC
    3-methyl-6-[4-(2-methylphenyl)phenyl]benzotriazole-4-carboxylic acid
    SMILES
    CC1=CC=CC=C1C2=CC=C(C=C2)C3=CC(=C4C(=C3)N=NN4C)C(=O)O
    InChIKey
    GSBZRCGZLMBSNY-UHFFFAOYSA-N
    InChI
    1S/C21H17N3O2/c1-13-5-3-4-6-17(13)15-9-7-14(8-10-15)16-11-18(21(25)26)20-19(12-16)22-23-24(20)2/h3-12H,1-2H3,(H,25,26)
    Sinónimos
    1H-​Benzotriazole-​7-​carboxylic acid,1-​methyl-​5-​(2'-​methyl[1,​1'-​biphenyl]​-​4-​yl)​-
  7. AG-636
    CAS: 1623416-31-8 Formula: C21H17N3O2 Peso molecular: 343.38
    10mM in DMSO
    En Stock Articulo #: A421973
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    Nombre IUPAC
    3-methyl-6-[4-(2-methylphenyl)phenyl]benzotriazole-4-carboxylic acid
    SMILES
    CC1=CC=CC=C1C2=CC=C(C=C2)C3=CC(=C4C(=C3)N=NN4C)C(=O)O
    InChIKey
    GSBZRCGZLMBSNY-UHFFFAOYSA-N
    InChI
    1S/C21H17N3O2/c1-13-5-3-4-6-17(13)15-9-7-14(8-10-15)16-11-18(21(25)26)20-19(12-16)22-23-24(20)2/h3-12H,1-2H3,(H,25,26)
    Sinónimos
    1H-​Benzotriazole-​7-​carboxylic acid,1-​methyl-​5-​(2'-​methyl[1,​1'-​biphenyl]​-​4-​yl)​-
  8. ASLAN003, Dihydroorotate dehydrogenase inhibitor
    CAS: 1035688-66-4 Formula: C19H14F2N2O3 Peso molecular: 356.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    En Stock Articulo #: A414476
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    Nombre IUPAC
    2-[2,6-difluoro-4-(3-methoxyphenyl)anilino]pyridine-3-carboxylic acid
    SMILES
    COC1=CC=CC(=C1)C2=CC(=C(C(=C2)F)NC3=C(C=CC=N3)C(=O)O)F
    InChIKey
    OMPATGZMNFWVOH-UHFFFAOYSA-N
    InChI
    1S/C19H14F2N2O3/c1-26-13-5-2-4-11(8-13)12-9-15(20)17(16(21)10-12)23-18-14(19(24)25)6-3-7-22-18/h2-10H,1H3,(H,22,23)(H,24,25)
    Sinónimos
    2-[2,6-difluoro-4-(3-methoxyphenyl)anilino]pyridine-3-carboxylic acid | ASALN003 | UNII-I58WE41H6X | MFCD32215342 | G...
  9. ASLAN003, Dihydroorotate dehydrogenase inhibitor
    CAS: 1035688-66-4 Formula: C19H14F2N2O3 Peso molecular: 356.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: A420429
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    Nombre IUPAC
    2-[2,6-difluoro-4-(3-methoxyphenyl)anilino]pyridine-3-carboxylic acid
    SMILES
    COC1=CC=CC(=C1)C2=CC(=C(C(=C2)F)NC3=C(C=CC=N3)C(=O)O)F
    InChIKey
    OMPATGZMNFWVOH-UHFFFAOYSA-N
    InChI
    1S/C19H14F2N2O3/c1-26-13-5-2-4-11(8-13)12-9-15(20)17(16(21)10-12)23-18-14(19(24)25)6-3-7-22-18/h2-10H,1H3,(H,22,23)(H,24,25)
    Sinónimos
    2-[2,6-difluoro-4-(3-methoxyphenyl)anilino]pyridine-3-carboxylic acid | ASALN003 | UNII-I58WE41H6X | MFCD32215342 | G...
  10. BAY 2402234, Inhibitor of dihydroorotate dehydrogenase (quinone)
    CAS: 2225819-06-5 Formula: C21H18ClF5N4O4 Peso molecular: 520.84
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    En Stock Articulo #: B414218
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    Nombre IUPAC
    N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-5-fluoro-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzamide
    SMILES
    CCN1C(=NN(C1=O)C2=C(C=C(C(=C2)OC(C)C(F)(F)F)C(=O)NC3=C(C=CC=C3Cl)F)F)CO
    InChIKey
    KNVJMHHAXCPZHF-JTQLQIEISA-N
    InChI
    1S/C21H18ClF5N4O4/c1-3-30-17(9-32)29-31(20(30)34)15-8-16(35-10(2)21(25,26)27)11(7-14(15)24)19(33)28-18-12(22)5-4-6-13(18)23/h4-8,10,32H,3,9H2,1-2H3,(Hshow more
    Sinónimos
    AKOS040741291 | s8847 | N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1...
  11. BAY 2402234, Inhibitor of dihydroorotate dehydrogenase (quinone)
    CAS: 2225819-06-5 Formula: C21H18ClF5N4O4 Peso molecular: 520.84
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: B422666
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    Nombre IUPAC
    N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-5-fluoro-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzamide
    SMILES
    CCN1C(=NN(C1=O)C2=C(C=C(C(=C2)OC(C)C(F)(F)F)C(=O)NC3=C(C=CC=C3Cl)F)F)CO
    InChIKey
    KNVJMHHAXCPZHF-JTQLQIEISA-N
    InChI
    1S/C21H18ClF5N4O4/c1-3-30-17(9-32)29-31(20(30)34)15-8-16(35-10(2)21(25,26)27)11(7-14(15)24)19(33)28-18-12(22)5-4-6-13(18)23/h4-8,10,32H,3,9H2,1-2H3,(Hshow more
    Sinónimos
    AKOS040741291 | s8847 | N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1...
  12. Brequinar, Dihydroorotate dehydrogenase inhibitor
    CAS: 96187-53-0 Número EC: 887-847-7 Formula: C23H15F2NO2 Peso molecular: 375.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: B427162
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    Identificadores técnicos
    Nombre IUPAC
    6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid
    SMILES
    CC1=C(C2=C(C=CC(=C2)F)N=C1C3=CC=C(C=C3)C4=CC=CC=C4F)C(=O)O
    InChIKey
    PHEZJEYUWHETKO-UHFFFAOYSA-N
    InChI
    1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28)
    Sinónimos
    BCP06006 | brequinarum | EX-A1515 | 2-(2'-Fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinolinecarboxylic acid | 4...
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