Mito-TEMPO - 10mM in DMSO , CAS No.1334850-99-5

CAS: 1334850-99-5 Cat. No.: M421267 Fórmula: C29H36ClN2O2P Peso molecular: 511
Disponible para pedir
GRADE & PURITY 10mM in DMSO
Synonyms
1-​Piperidinyloxy,2,​2,​6,​6-​tetramethyl-​4-​[[2-​(triphenylphosphonio​)​acetyl]​amino]​-​,chloride (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
Alemania (EU)*
Price
Qty
1ml
M421267-1ml
2 Disponible
—
51,90US$
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Mito-TEMPO Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced RIP3 kinase expression.

Targets

RIP3 kinase

In vitro

Mito-TEMPO improves blastocyst development by superoxide reduction in porcine embryos in vitro.

In vivo

Mito-Tempo (MT) treatment inhibits APAP-induced RIP3 kinase expression, and RIP3-deficient mice shows caspase activation and apoptotic morphology in hepatocytes analogous to MT treatment.

Cell Research(from reference)

Cell lines:Porcine embryos 

Concentrations:0.1\u2009μM 

Specifications

Sinónimos
1-​Piperidinyloxy,2,​2,​6,​6-​tetramethyl-​4-​[[2-​(triphenylphosphonio​)​acetyl]​amino]​-​,chloride (1:1)
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced RIP3 kinase expression.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores
Pubchem Sid
Sonrisas canónicas
CC1(CC(CC(N1O)(C)C)NC(=O)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Cl-]
IUPAC Name
[2-[(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)amino]-2-oxoethyl]-triphenylphosphanium;chloride
InChIKey
QJEOOHMMSUBNGG-UHFFFAOYSA-N
INCHI
1S/C29H35N2O2P.ClH/c1-28(2)20-23(21-29(3,4)31(28)33)30-27(32)22-34(24-14-8-5-9-15-24,25-16-10-6-11-17-25)26-18-12-7-13-19-26;/h5-19,23,33H,20-22H2,1-4H3;1H
WGK Alemania
3
Peso molecular
511
Reaxy-Rn
34662187
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34662187&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Preguntas frecuentes y artículos
Citations of This Product
Calculadoras de soluciones
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